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Results for “Central Nervous System Degenerative Disorder”

908 trials

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Showing 20 of 908 results

Not applicableLooking for participantsNCT07019558
What this trial is testing

Ophthalmological Disorders in Dominant Spinal-cerebellar Ataxias

Who this might be right for
Spinocerebellar Ataxia
University Hospital, Montpellier 60
Large-scale testing (Phase 3)Ended earlyNCT05328908
What this trial is testing

Nivolumab-relatlimab Fixed-dose Combination Versus Regorafenib or TAS-102 in Participants With Later-lines of Metastatic Colorectal Cancer

Who this might be right for
Colorectal Neoplasms
Bristol-Myers Squibb 770
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07173933
What this trial is testing

Phase I/II Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of GC310 Injection in Patients With Wilson's Disease (WD)

Who this might be right for
Wilson Disease
GeneCradle Inc 15
Early research (Phase 1)Study completedNCT03636204
What this trial is testing

A First in Human Study in Healthy Volunteers and in Participants With Frontotemporal Dementia With Granulin (GRN) Mutation

Who this might be right for
HealthyFrontotemporal Dementia
Alector Inc. 64
Not applicableStudy completedNCT06762509
What this trial is testing

The Clinical Study of Botulinum Toxin Type A Injection in the Treatment of Wilson Disease

Who this might be right for
Wilson Disease
The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine 60
Not applicableActive Not RecruitingNCT04516499
What this trial is testing

Neurofilament Surveillance Project (NSP)

Who this might be right for
Frontotemporal DementiaFrontotemporal Lobar DegenerationFTD-GRN+2 more
The Bluefield Project to Cure Frontotemporal Dementia 342
Not applicableStudy completedNCT06539598
What this trial is testing

Respiratory Training in Friedreich's Ataxia

Who this might be right for
Friedreich Ataxia
University of Florida 1
Not applicableNot Yet RecruitingNCT07241832
What this trial is testing

Multifaceted Assessment of Patients With Wilson's Disease in a Low-Resource Setting in Upper Egypt: Service Integration, Psychosocial Burden, Dietary Practices, and the Geo-Spatial Disease Map

Who this might be right for
Wilson's Disease
Assiut University 66
Testing effectiveness (Phase 2)Looking for participantsNCT06823752
What this trial is testing

A Dual Orexin Receptor Antagonist to Reduce Biomarkers of Neurodegeneration in Adults With Insomnia.

Who this might be right for
Insomnia
Woolcock Institute of Medical Research 20
Not applicableStudy completedNCT03430648
What this trial is testing

Is Tau Protein Linked to Mobility Function?

Who this might be right for
Alzheimer DiseasePhysical Activity
Wake Forest University Health Sciences 37
Not applicableNot Yet RecruitingNCT06177626
What this trial is testing

Use of a New Smartphone Application to Determine Changes in Eyeblink Conditioning From Home Training in Individuals With Spinocerebellar Ataxia

Who this might be right for
Spinocerebellar Ataxias
Columbia University 30
Not applicableLooking for participantsNCT02945774
What this trial is testing

Molecular Neuroimaging of Neuroinflammation in Neurodegenerative Dementias

Who this might be right for
Frontotemporal Dementia
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 40
Not applicableStudy completedNCT03687190
What this trial is testing

Could Tai-chi Help Maintain Balance of Spinocerebellar Ataxia Patients

Who this might be right for
Spinocerebellar AtaxiasTai Chi
Changhua Christian Hospital 21
Not applicableLooking for participantsNCT06573723
What this trial is testing

Institutional Registry of Rare Diseases

Who this might be right for
Rare DiseasesAmyloidosisSarcoidosis+23 more
Hospital Italiano de Buenos Aires 380
Testing effectiveness (Phase 2)Study completedNCT02676843
What this trial is testing

Tau PET Imaging With 18F-AV-1451 in Subjects With MAPT Mutations

Who this might be right for
Frontotemporal Lobar Degeneration (FTLD)Frontotemporal Dementia (FTD)Tauopathies
Columbia University 7
Testing effectiveness (Phase 2)Study completedNCT02983708
What this trial is testing

Neuroregenerative Potential of Intravenous G-CSF and Autologous Peripheral Blood Stem Cells

Who this might be right for
NeurodegenerationG-CSFPeripheral Blood Mononuclear Cells+1 more
Hanyang University Seoul Hospital 57
Not applicableUnknownNCT04589182
What this trial is testing

Assessing the Symptomatic Benefit of Acoustic Slow Wave Enhancement in Parkinson Disease

Who this might be right for
Parkinson DiseaseMild Cognitive ImpairmentHuntington Disease
Christian Baumann 12
Post-approval studies (Phase 4)Study completedNCT04679935
What this trial is testing

Efficacy and Safety of Two Different Brolucizumab 6 mg Dosing Regimens in Neovascular Age-related Macular Degeneration

Who this might be right for
Age-related Macular Degeneration
Novartis Pharmaceuticals 52
Not applicableLooking for participantsNCT02435940
What this trial is testing

Inherited Retinal Degenerative Disease Registry

Who this might be right for
Eye Diseases HereditaryRetinal DiseaseAchromatopsia+25 more
Foundation Fighting Blindness 20,000
Not applicableLooking for participantsNCT06339190
What this trial is testing

Neurofilament Light Chain And Voice Acoustic Analyses In Dementia Diagnosis

Who this might be right for
Neurodegenerative DiseasesDementia
Monash University 1,000
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