Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Central Nervous System Degenerative Disorder”

966 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 966 results

Not applicableStudy completedNCT02912936
What this trial is testing

A Medium Chain Triglyceride Intervention for Patients With Alzheimer Disease

Who this might be right for
Alzheimer's DiseasePrimary Progressive Non-fluent AphasiaFrontotemporal Dementia (FTD)
University of British Columbia 43
Early research (Phase 1)Study completedNCT01581411
What this trial is testing

Intra-arterial Thrombolysis for Severe Recent Central Retinal Vein Occlusion

Who this might be right for
Central Retinal Vein Occlusion
Weill Medical College of Cornell University 1
Not applicableLooking for participantsNCT07636135
What this trial is testing

Timing of Rehabilitation Following Cervical Spinal Surgery in Degenerative Myelopathy

Who this might be right for
Cervical Myelopathy
University of Alberta 20
Large-scale testing (Phase 3)Ended earlyNCT00818389
What this trial is testing

Study to Investigate the Safety and Efficacy of Lithium in Volunteers With Amyotrophic Lateral Sclerosis (ALS)

Who this might be right for
Amyotrophic Lateral Sclerosis
Massachusetts General Hospital 84
Not applicableLooking for participantsNCT03848663
What this trial is testing

Visual Remapping to Aid Reading With Field Loss

Who this might be right for
Age-related Macular Degeneration
University of Minnesota 108
Early research (Phase 1)Study completedNCT02031198
What this trial is testing

18-months Safety Follow-up Study of AADvac1, an Active Tau Vaccine for Alzheimer's Disease

Who this might be right for
Alzheimer's Disease
Axon Neuroscience SE 25
Post-approval studies (Phase 4)WithdrawnNCT00127114
What this trial is testing

Amantadine for the Treatment of Behavioral Disturbance in Frontotemporal Dementia (FTD)

Who this might be right for
Dementia
Johns Hopkins University
Not applicableStudy completedNCT01925196
What this trial is testing

Natural History and Biomarkers of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Caused by the C9ORF72 Gene Mutation

Who this might be right for
Amyotrophic Lateral SclerosisFrontotemporal Lobar Degeneration
National Institute of Neurological Disorders and Stroke (NINDS) 50
Large-scale testing (Phase 3)Looking for participantsNCT05456503
What this trial is testing

PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620

Who this might be right for
Frontotemporal Lobar DegenerationAlzheimer DiseaseCognitively Normal
University of Pennsylvania 72
Testing effectiveness (Phase 2)Study completedNCT01965327
What this trial is testing

Interferon Gamma-1b in Friedreich Ataxia (FRDA)

Who this might be right for
Friedreich Ataxia
Children's Hospital of Philadelphia 12
Testing effectiveness (Phase 2)Study completedNCT02147886
What this trial is testing

Study To Assess Safety, Tolerability and Efficacy of Intravenous Cabaletta in Patients With Machado-Joseph Disease

Who this might be right for
Machado-Joseph Disease / Spinocerebellar Ataxia 3
Bioblast Pharma Ltd. 15
Not applicableStudy completedNCT04014673
What this trial is testing

Natural History Characterization in Symptomatic and Asymptomatic Progranuline Gene Mutation Carriers

Who this might be right for
Frontotemporal Lobar Degeneration
Assistance Publique - Hôpitaux de Paris 78
Post-approval studies (Phase 4)Ended earlyNCT01319188
What this trial is testing

Ranibizumab and the Risk of Arterial Thromboembolic Events

Who this might be right for
Age-related Macular DegenerationCoronary Artery DiseaseCerebrovascular Disorders
Ural State Medical University 380
Early research (Phase 1)UnknownNCT04432857
What this trial is testing

AN0025 and Pembrolizumab Combination in Advanced Solid Tumors

Who this might be right for
Triple-negative Breast CancerNSCLC, Squamous or Non-SquamousUrothelial Carcinoma of the Bladder+2 more
Adlai Nortye Biopharma Co., Ltd. 63
Testing effectiveness (Phase 2)Study completedNCT07010575
What this trial is testing

Patient Preference Study: Standard of Care Versus Once-daily Trientine Tetrahydrochloride

Who this might be right for
Wilson's Disease
Orphalan 10
Not applicableEnrolling By InvitationNCT07716930
What this trial is testing

Retinal OCT Changes and Biomarkers in Drug-Resistant Epilepsy

Who this might be right for
Epilepsy (Treatment Refractory)Epilepsy
Kemal Tutkavul 250
Not applicableUnknownNCT06320444
What this trial is testing

Non-invasive Spinal, Cortical, and Sensorimotor Biomarkers in Motor Neurone Disease

Who this might be right for
Motor Neuron Disease, Amyotrophic Lateral SclerosisMotor Neuron Disease Progressive Spinal Muscle AtrophyPrimary Lateral Sclerosis+2 more
University of Dublin, Trinity College 240
Testing effectiveness (Phase 2)Study completedNCT00703677
What this trial is testing

A Pilot Trial of Lithium in Subjects With Progressive Supranuclear Palsy or Corticobasal Degeneration

Who this might be right for
Progressive Supranuclear PalsyCorticobasal Degeneration
Westat 17
Not applicableStudy completedNCT01168466
What this trial is testing

EEG Biofeedback to Improve Memory in Adults With Dementia

Who this might be right for
Dementia
Quietmind Foundation 37
Not applicableLooking for participantsNCT06600269
What this trial is testing

Cycling-Based Priming Coordination Training for Enhancing Ataxia Recovery and Brain Plasticity

Who this might be right for
Spinocerebellar Ataxias
Chang Gung University 40
Next Page