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Results for “Checkpoint Inhibitor”

718 trials

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Showing 20 of 718 results

Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Not applicableNot Yet RecruitingNCT07257068
What this trial is testing

Checkpoint Inhibitor Associated Diabetes Mellitus: Early Recognition and Treatment (CERT) Project: A Pilot Study

Who this might be right for
Checkpoint InhibitorPilot StudyDiabetes Melletus
M.D. Anderson Cancer Center 14
Large-scale testing (Phase 3)Looking for participantsNCT06340568
What this trial is testing

A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer

Who this might be right for
Endometrial Cancer
BioNTech SE 480
Not applicableLooking for participantsNCT06738797
What this trial is testing

Association Between the SPHERTEST in Vitro Test and Response to Checkpoint Inhibitor Treatments in Patients With Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Urogenital Neoplasms
Centre Hospitalier Universitaire de Nīmes 32
Not applicableUnknownNCT06309862
What this trial is testing

Immune Checkpoint Inhibitor Therapy for Cancer and Risk of Myocarditis or Cardiomyopathy

Who this might be right for
Cardio-OncologyCardiomyopathy Due to Drug
Sunnybrook Health Sciences Centre 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT02935361
What this trial is testing

Guadecitabine and Atezolizumab in Treating Patients With Advanced Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia That Is Refractory or Relapsed

Who this might be right for
Chronic Myelomonocytic LeukemiaMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes
University of Southern California 33
Not applicableEnded earlyNCT04577729
What this trial is testing

The IRMI-FMT Trial

Who this might be right for
Fecal Microbiota TransplantationMalignant Melanoma Stage IIIMalignant Melanoma Stage IV
Medical University of Graz 5
Testing effectiveness (Phase 2)Study completedNCT03988036
What this trial is testing

A Study With Pembrolizumab in Combination With Dual Anti-HER2 Blockade With Trastuzumab and Pertuzumab in Early Breast Cancer Patients With Molecular HER2-enriched Intrinsic Subtype (Keyriched-1)

Who this might be right for
Breast Cancer
Women's Cancer Study Group GmbH 46
Not applicableNot Yet RecruitingNCT07689812
What this trial is testing

Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced / Metastatic Solid Tumors.

Who this might be right for
NSCLC (Advanced Non-small Cell Lung Cancer)NSCLC (Non-small Cell Lung Cancer)NSCLC (Non-small Cell Lung Carcinoma)+12 more
Natera, Inc. 920
Testing effectiveness (Phase 2)Looking for participantsNCT07262619
What this trial is testing

EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

Who this might be right for
Advanced Solid TumorsMSI-H or dMMR Advanced Solid TumorsMSI-H/dMMR Gastric Cancer+4 more
Eikon Therapeutics 160
Large-scale testing (Phase 3)Looking for participantsNCT06958432
What this trial is testing

Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II)

Who this might be right for
Rectal CancerNeoadjuvant TherapiesImmune Checkpoint Therapy+1 more
Sixth Affiliated Hospital, Sun Yat-sen University 430
Early research (Phase 1)Study completedNCT05396833
What this trial is testing

Study of Tuvusertib (M1774) in Combination With DNA Damage Response Inhibitor or Immune Checkpoint Inhibitor (DDRiver Solid Tumors 320)

Who this might be right for
Metastatic or Locally Advanced Unresectable Solid Tumors
EMD Serono Research & Development Institute, Inc. 120
Not applicableEnded earlyNCT05812274
What this trial is testing

Apricity CARE to Improve ICI Outcomes of Ethnic/Racial Minority NSCLC Patients

Who this might be right for
Non Small Cell Lung Cancer
Columbia University 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07267234
What this trial is testing

PRaG-1 Plus PRaG Therapy in Advanced Solid Tumors: A Prospective Clinical Trial (PRaG 10.0)

Who this might be right for
Solid CancerLymphopeniaRadiotherapy+1 more
Second Affiliated Hospital of Soochow University 65
Testing effectiveness (Phase 2)Looking for participantsNCT04592211
What this trial is testing

Pembrolizumab, Olaparib, Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer

Who this might be right for
Gastric Cancer Stage IV
Yonsei University 71
Not applicableNot Yet RecruitingNCT07233668
What this trial is testing

Immediate Versus Deferred Cytoreductive Nephrectomy With Ipilimumab/Nivolumab in mRCC

Who this might be right for
Metastatic Renal Cell Carcinoma ( mRCC)
Seoul National University Hospital 172
Not applicableLooking for participantsNCT07161310
What this trial is testing

Urolithin A in Patients With Previously Untreated Solid Tumors Receiving Immune Checkpoint Inhibitors

Who this might be right for
Solid CancerNon-Small Cell Lung CancerMelanoma
Goethe University 45
Testing effectiveness (Phase 2)Ended earlyNCT06006923
What this trial is testing

Regorafenib in Combination With Pembrolizumab or Pembrolizumab for MSI-H Colorectal Cancer

Who this might be right for
MSI-H Colorectal Cancer
Anwaar Saeed 1
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07530224
What this trial is testing

JAK Inhibitors for Solid Malignant Tumor Patients With Refractory Immune Checkpoint Inhibitors-related Dermatitis

Who this might be right for
Immune Checkpoint Inhibitor-Induced Dermatitis
Shixiu Wu 35
Testing effectiveness (Phase 2)Looking for participantsNCT05758389
What this trial is testing

Tislelizumab Combined APF Chemotherapy in the Treatment of Locally Advanced Head and Neck Tumors

Who this might be right for
Head and Neck Tumors
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 29
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