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Results for “Checkpoint Inhibitor”

663 trials

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Showing 20 of 663 results

Large-scale testing (Phase 3)Looking for participantsNCT06989112
What this trial is testing

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Who this might be right for
Endometrial Cancer
AstraZeneca 600
Testing effectiveness (Phase 2)Looking for participantsNCT03645928
What this trial is testing

Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors

Who this might be right for
Metastatic MelanomaSquamous Cell Carcinoma of the Head and NeckNon-small Cell Lung Cancer
Iovance Biotherapeutics, Inc. 245
Early research (Phase 1)Ended earlyNCT02936102
What this trial is testing

FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.

Who this might be right for
Advanced Solid TumorsTriple Negative Breast CancerChordoma and Alveolar Soft Part Sarcoma
Novartis Pharmaceuticals 154
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07376499
What this trial is testing

Prospective, Single-arm, Phase II Clinical Study of Irinotecan Hydrochloride Liposome Injection Combined With Platinum and Immune Checkpoint Inhibitors Combined With Anlotinib for the Maintenance of Extensive Small Cell Lung Cancer After First-line Induction

Who this might be right for
Small Cell Lung Cancer
China Medical University, China 31
Not applicableUnknownNCT05554432
What this trial is testing

Development of an EORTC Immune Checkpoint Inhibitor-specific Quality of Life Item List: Phase 1 & 2

Who this might be right for
CancerIMMUNE CHECKPOINT INHIBITORQuality of Life
Institut Curie 43
Not applicableLooking for participantsNCT07191171
What this trial is testing

Impact of Dysbiosis-inducing Drugs on Effectivity of Immune Checkpoint Inhibitor in Non-small Cell Lung Cancer Patients

Who this might be right for
Dysbiosis
University Hospital, Strasbourg, France 800
Not applicableActive Not RecruitingNCT06632106
What this trial is testing

HAIC in Combination with Immune Checkpoint Inhibitors and Tyrosine Kinase Inhibitors for Advanced HCC

Who this might be right for
Hepatic Arterial Infusion ChemotherapyTyrosine Kinase InhibitorImmune Checkpoint Inhibitors+1 more
First Hospital of China Medical University 97
Early research (Phase 1)Ended earlyNCT03237572
What this trial is testing

Focused Ultrasound and Pembrolizumab in Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Patrick Dillon, MD 13
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05741164
What this trial is testing

Propranolol and Pembrolizumab for Tumor Re-sensitization and Treatment of Patients With Checkpoint Inhibitor Refractory Metastatic or Unresectable Triple Negative Breast Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Triple-Negative Breast Carcinoma+2 more
Emory University 37
Testing effectiveness (Phase 2)UnknownNCT06132698
What this trial is testing

Immune Checkpoint Inhibitors Intrathecal Injection in Patients With Leptomeningeal Metastases in NSCLC

Who this might be right for
NSCLC Associated With Leptomeningeal Metastases
West China Hospital 17
Not applicableStudy completedNCT05221398
What this trial is testing

Adjuvant Immune Checkpoint Inhibitors in Postoperative Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Guangxi Medical University 517
Testing effectiveness (Phase 2)Study completedNCT04507906
What this trial is testing

Nivolumab Combined With Anlotinib as Re-challenge Treatment in Advanced NSCLC

Who this might be right for
NSCLC Stage IVCheckpoint Inhibitor
Shanghai Chest Hospital 21
Testing effectiveness (Phase 2)Study completedNCT03325816
What this trial is testing

Nivolumab and 177Lu-DOTA0-Tyr3-Octreotate for Patients With Extensive-Stage Small Cell Lung Cancer

Who this might be right for
Small Cell Lung CancerSmall Cell Lung Cancer Extensive Stage
Georgetown University 9
Not applicableLooking for participantsNCT06566209
What this trial is testing

FDG-PET as an Imaging Modality to Diagnose and Risk Stratify Subclinical, Imaging Negative Ici-Myocarditis

Who this might be right for
Subclinical Immune Checkpoint Inhibitor-Induced MyocarditisMyocarditisICI-Myocarditis+4 more
Mayo Clinic 30
Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07244965
What this trial is testing

Neoadjuvant Ivonescimab Plus Chemotherapy Followed by Concurrent Chemoradiotherapy in High-Risk Locally Advanced Cervical Cancer

Who this might be right for
LOCALLY ADVANCED CERVICAL CANCERS
Women's Hospital School Of Medicine Zhejiang University 42
Testing effectiveness (Phase 2)Looking for participantsNCT05128201
What this trial is testing

Consolidative Radiotherapy Combined With Camrelizumab and Chemotherapy for Oligometastatic Nasopharyngeal Carcinoma

Who this might be right for
Oligometastatic Disease
Jiangxi Provincial Cancer Hospital 63
Not applicableLooking for participantsNCT07423169
What this trial is testing

Partial Tumor Irradiation and Immunotherapy for Unresectable Lung Cancer

Who this might be right for
Lung AdenocarcinomaBulky TumorsUnresectable Cancer
Karl Landsteiner University of Health Sciences 10
Not applicableLooking for participantsNCT07302074
What this trial is testing

Understanding of Rare Inflammatory Arthritis in Comparison to Classical Inflammatory Arthritis : Tissular Observations and Immune Infiltrate Characterization : the UTOPIC Project

Who this might be right for
Inflammatory ArthritisRare Auto-immune DiseasesImmune Checkpoint Inhibitor Related Inflamamtory Arthritis
University Hospital, Brest 100
Early research (Phase 1)Ended earlyNCT03735290
What this trial is testing

Evaluate the Safety and Effectiveness of ILIxadencel Administered Into Tumors in Combination With Checkpoint Inhibitor (CPI) in Patients With ADvanced Cancer

Who this might be right for
Carcinoma, Squamous Cell of Head and NeckGastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma+1 more
Mendus 21
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