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Results for “Checkpoint Inhibitor”

651 trials

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Showing 20 of 651 results

Testing effectiveness (Phase 2)WithdrawnNCT06557278
What this trial is testing

Combined AlloStim+Anti-PD-L1 in 4L MSS Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Mirror Biologics, Inc.
Not applicableLooking for participantsNCT06132984
What this trial is testing

Cardiac Magnetic Resonance Monitoring of Immune Checkpoint Inhibitor-related Cardiotoxicity

Who this might be right for
Immune Checkpoint Inhibitors, Cardiotoxicity
West China Second University Hospital 22
Not applicableLooking for participantsNCT06818149
What this trial is testing

Biomarkers for Clinical Classification and Outcomes of Immune Checkpoint Inhibitor-Related-Related Myocarditis in Lung Cancer

Who this might be right for
Lung CancerMyocarditis Due to Drug
Shanghai Chest Hospital 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05445648
What this trial is testing

Comprehensive Bladder Preservation Therapy on Patients With Muscle Invasive Bladder Cancer

Who this might be right for
Urinary Bladder Neoplasms
First Affiliated Hospital Xi'an Jiaotong University 65
Testing effectiveness (Phase 2)Active Not RecruitingNCT05012371
What this trial is testing

Lenvatinib With Everolimus Versus Cabozantinib for Second-Line or Third-Line Treatment of Metastatic Renal Cell Cancer

Who this might be right for
Advanced Clear Cell Renal Cell CarcinomaMetastatic Clear Cell Renal Cell CarcinomaStage III Renal Cell Cancer AJCC v8+1 more
M.D. Anderson Cancer Center 90
Testing effectiveness (Phase 2)Looking for participantsNCT04592211
What this trial is testing

Pembrolizumab, Olaparib, Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer

Who this might be right for
Gastric Cancer Stage IV
Yonsei University 71
Early research (Phase 1)Looking for participantsNCT05859074
What this trial is testing

MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer

Who this might be right for
Cutaneous Squamous Cell CarcinomaSCC - Squamous Cell CarcinomaBasal Cell Carcinoma+16 more
Memorial Sloan Kettering Cancer Center 56
Testing effectiveness (Phase 2)Active Not RecruitingNCT04706715
What this trial is testing

LAG3 PET Imaging in Advanced Solid Tumors

Who this might be right for
Metastatic Solid Tumor
University Medical Center Groningen 41
Testing effectiveness (Phase 2)Active Not RecruitingNCT02935361
What this trial is testing

Guadecitabine and Atezolizumab in Treating Patients With Advanced Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia That Is Refractory or Relapsed

Who this might be right for
Chronic Myelomonocytic LeukemiaMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes
University of Southern California 33
Testing effectiveness (Phase 2)Looking for participantsNCT06772623
What this trial is testing

Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations

Who this might be right for
Non Small Cell Lung Carcinoma
AbbVie 252
Testing effectiveness (Phase 2)Study completedNCT02073123
What this trial is testing

Study of IDO Inhibitor in Combination With Checkpoint Inhibitors for Adult Patients With Metastatic Melanoma

Who this might be right for
Metastatic MelanomaStage III MelanomaStage IV Melanoma
NewLink Genetics Corporation 132
Not applicableUnknownNCT06192303
What this trial is testing

Prospective Study on the Efficacy and Safety of Bronchoalveolar Lavage Combined With Pathogen Metagenomic Sequencing Technology in the Diagnosis of Immune Checkpoint Inhibitor Associated Pneumonia

Who this might be right for
Immune Checkpoint Inhibitor Associated Pneumonia
Nanfang Hospital, Southern Medical University 104
Early research (Phase 1)Looking for participantsNCT07161414
What this trial is testing

Investigate the Pharmacokinetics and Safety of Subcutaneous Rilvegostomig in Adult Participants With Advanced Solid Tumors Previously Treated With Standard of Care Therapy

Who this might be right for
Advanced Solid Tumors
AstraZeneca 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT05529316
What this trial is testing

Botensilimab (AGEN1181) for the Treatment of Advanced Melanoma

Who this might be right for
Advanced Melanoma
Agenus Inc. 150
Testing effectiveness (Phase 2)Ended earlyNCT04214418
What this trial is testing

Study of Combination Therapy With the MEK Inhibitor, Cobimetinib, Immune Checkpoint Blockade, Atezolizumab, and the AUTOphagy Inhibitor, Hydroxychloroquine in KRAS-mutated Advanced Malignancies

Who this might be right for
Gastrointestinal Cancer
Columbia University 27
Testing effectiveness (Phase 2)Ended earlyNCT05935748
What this trial is testing

Ph2 Study NKT2152 With Palbociclib & Sasanlimab in Subjects With Advanced Clear Cell Renal Cell Carcinoma (ccRcc)

Who this might be right for
ccRCCClear Cell Renal Cell CarcinomaKidney Cancer+18 more
NiKang Therapeutics, Inc. 18
Large-scale testing (Phase 3)Looking for participantsNCT06958432
What this trial is testing

Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II)

Who this might be right for
Rectal CancerNeoadjuvant TherapiesImmune Checkpoint Therapy+1 more
Sixth Affiliated Hospital, Sun Yat-sen University 430
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07381634
What this trial is testing

The Safety and Efficacy of Ondansetron in Reducing Immune Checkpoint Inhibitor-Related Toxicities

Who this might be right for
Hepatocellular Carcinoma (HCC)IrAE
First Affiliated Hospital of Wenzhou Medical University 66
Testing effectiveness (Phase 2)Looking for participantsNCT04260256
What this trial is testing

A Study Using [18F]F AraG PET to Evaluate Response to Checkpoint Inhibitor Therapy(CkIT) in Patients With Solid Tumors

Who this might be right for
Correlate Tracer Uptake to TCell Tumor Infiltration & CkIT Benefit
CellSight Technologies, Inc. 40
Testing effectiveness (Phase 2)Study completedNCT02404441
What this trial is testing

Phase I/II Study of PDR001 in Patients With Advanced Malignancies

Who this might be right for
MelanomaNon-small Sell Lung Cancer (NSCLC)Triple Negative Breast Cancer+2 more
Novartis Pharmaceuticals 319
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