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Results for “Child-Pugh Class A”

23 trials

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Showing 20 of 23 results

Testing effectiveness (Phase 2)Study completedNCT02994056
What this trial is testing

Evaluate the Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed-Dose Combination and Ribavirin for 12 Weeks in Participants With Chronic HCV Infection and Child-Pugh-Turcotte Class C Cirrhosis

Who this might be right for
Hepatitis C Virus Infection
Gilead Sciences 32
Early research (Phase 1)WithdrawnNCT02989870
What this trial is testing

Sorafenib and Bavituximab Plus SBRT in Unresectable Hepatocellular Carcinoma

Who this might be right for
HepatoCellular CarcinomaUnresectable HepatoCellular CarcinomaLiver Cancer
H. Lee Moffitt Cancer Center and Research Institute
Testing effectiveness (Phase 2)Study completedNCT02115373
What this trial is testing

C-Met Second-Line Hepatocellular Carcinoma

Who this might be right for
Carcinoma, Hepatocellular
Merck KGaA, Darmstadt, Germany 66
Post-approval studies (Phase 4)Study completedNCT01846455
What this trial is testing

Single Dose Pharmacokinetics of Suboxone Study in Hepatic Impaired Subjects

Who this might be right for
Hepatic FailureHepatic ImpairmentChronic Hepatitis C Infection With Hepatic Coma
Indivior Inc. 43
Early research (Phase 1)Study completedNCT06957756
What this trial is testing

Test How BI 1584862 is Taken up in the Blood of People With and Without Liver Problems

Who this might be right for
Hepatic Insufficiency
Boehringer Ingelheim 43
Early research (Phase 1)Not Yet RecruitingNCT07550634
What this trial is testing

Pharmacokinetics and Safety of MDR-001 in Mild and Moderate Hepatic Impairment

Who this might be right for
Hepatic Impairment (Mild and Moderate, Child-Pugh Class A and B)Hepatic Insufficiency (MeSH ID: D048550)
MindRank AI Ltd 32
Large-scale testing (Phase 3)Looking for participantsNCT05201404
What this trial is testing

Namodenoson in the Treatment of Advanced Hepatocellular Carcinoma in Patients With Child-Pugh Class B7 Cirrhosis

Who this might be right for
Hepatocellular CarcinomaCirrhosis
Can-Fite BioPharma 471
Early research (Phase 1)Study completedNCT02256033
What this trial is testing

Effect of Mild Hepatic Impairment on the Pharmacokinetics of Istradefylline

Who this might be right for
Hepatic Impairment
Kyowa Kirin Co., Ltd. 20
Early research (Phase 1)Ended earlyNCT04136444
What this trial is testing

A Pharmacokinetic Study of Padsevonil in Study Participants With Either Normal or Moderately Impaired Hepatic Function

Who this might be right for
Healthy Study ParticipantsImpaired Hepatic Function
UCB Biopharma S.P.R.L. 12
Large-scale testing (Phase 3)UnknownNCT00921531
What this trial is testing

Adjuvant Therapy With Thalidomide for Chemoembolization in Advanced Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Fudan University 200
Testing effectiveness (Phase 2)Study completedNCT03109886
What this trial is testing

Study of Milciclib in Patients With Unresectable/Metastatic Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Tiziana Life Sciences LTD 31
Testing effectiveness (Phase 2)Study completedNCT01988493
What this trial is testing

Efficacy, Safety, and Pharmacokinetic of MSC2156119J in Asian Participants With Hepatocellular Carcinoma

Who this might be right for
Carcinoma, Hepatocellular
Merck KGaA, Darmstadt, Germany 117
Early research (Phase 1)Study completedNCT06888115
What this trial is testing

The Pharmacokinetics and Safety of CS0159 in Subjects With Hepatic Injury

Who this might be right for
Primary Biliary Cholangitis
Cascade Pharmaceuticals, Inc 24
Testing effectiveness (Phase 2)Study completedNCT02128958
What this trial is testing

Phase 2, Randomized, Double-Blind, Placebo-Controlled of the Efficacy and Safety of CF102 in Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma
Can-Fite BioPharma 78
Large-scale testing (Phase 3)Ended earlyNCT02762266
What this trial is testing

Transarterial Chemoembolization Compared With Stereotactic Body Radiation Therapy or Stereotactic Ablative Radiation Therapy in Treating Patients With Residual or Recurrent Liver Cancer Undergone Initial Transarterial Chemoembolization

Who this might be right for
Child-Pugh Class AChild-Pugh Class BRecurrent Hepatocellular Carcinoma
Stanford University 13
Testing effectiveness (Phase 2)Study completedNCT01188733
What this trial is testing

Efficacy of Long-acting Octreotide (Sandostatin LAR) in Reducing Portal Pressure in Patients With Cirrhosis

Who this might be right for
CirrhosisPortal HypertensionEsophageal Varices
Mayo Clinic 39
Early research (Phase 1)Looking for participantsNCT07694843
What this trial is testing

A Phase I Clinical Trial to Evaluate the Pharmacokinetic and Safety of Ammoxetine Hydrochloride Enteric-Coated Tablets in Participants With Mild Hepatic Impairment, Moderate Hepatic Impairment, and Normal Liver Function

Who this might be right for
Healthy ParticipantsParticipants With Mild Hepatic ImpairmentParticipants With Moderate Hepatic Impairment
CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 24
Early research (Phase 1)Not Yet RecruitingNCT06994572
What this trial is testing

Study of CT-01 as Monotherapy and Combination Therapy in Subjects With Intermediate or Advanced Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma (HCC)
Captor Therapeutics S.A. 141
Early research (Phase 1)Study completedNCT05088642
What this trial is testing

A Trial of Hetrombopag in Healthy and Hepatic Impairment Subjects

Who this might be right for
Sever Aplastic Anaemia
Jiangsu HengRui Medicine Co., Ltd. 24
Testing effectiveness (Phase 2)Study completedNCT00073736
What this trial is testing

Safety and Tolerability of I.V. Infusion of MB07133 in Patients With Unresectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Ligand Pharmaceuticals 28
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