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Results for “Childhood Diffuse Intrinsic Pontine Glioma”

15 trials

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Showing 15 of 15 results

Early research (Phase 1)Looking for participantsNCT06894979
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

Who this might be right for
Childhood AstrocytomaChildhood Diffuse Intrinsic Pontine GliomaChildhood Diffuse Midline Glioma+2 more
Children's Oncology Group 54
Testing effectiveness (Phase 2)Study completedNCT00028795
What this trial is testing

Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Children's Oncology Group 170
Early research (Phase 1)Looking for participantsNCT04943848
What this trial is testing

RHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-Mutant
Ann & Robert H Lurie Children's Hospital of Chicago 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT03709680
What this trial is testing

Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors

Who this might be right for
Ewing SarcomaSolid TumorsRhabdoid Tumor+4 more
Pfizer 128
Testing effectiveness (Phase 2)Active Not RecruitingNCT04758533
What this trial is testing

Clinical Trial to Assess the Safety and Efficacy of AloCELYVIR With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) in Combination With Radiotherapy or Medulloblastoma in Monotherapy

Who this might be right for
Diffuse Intrinsic Pontine GliomaMedulloblastoma, Childhood, Recurrent
Hospital Infantil Universitario Niño Jesús, Madrid, Spain 13
Early research (Phase 1)Active Not RecruitingNCT05768880
What this trial is testing

Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline GliomaRecurrent CNS Tumor, Adult+2 more
Seattle Children's Hospital 72
Early research (Phase 1)Looking for participantsNCT04185038
What this trial is testing

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Who this might be right for
Central Nervous System TumorDiffuse Intrinsic Pontine GliomaDiffuse Midline Glioma+8 more
Seattle Children's Hospital 90
Not applicableLooking for participantsNCT01106794
What this trial is testing

Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma

Who this might be right for
Diffuse Intrinsic Pontine GliomaBrainstem Glioma
Children's National Research Institute 100
Early research (Phase 1)Study completedNCT02444546
What this trial is testing

Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Relapsed or Refractory Brain Tumors

Who this might be right for
Childhood AstrocytomaChildhood Atypical Teratoid/Rhabdoid TumorDiffuse Intrinsic Pontine Glioma+7 more
Mayo Clinic 6
Early research (Phase 1)Looking for participantsNCT05298995
What this trial is testing

GD2-CAR T Cells for Pediatric Brain Tumours

Who this might be right for
Brain Tumor, PediatricMedulloblastoma, ChildhoodEmbryonal Tumor+4 more
Bambino Gesù Hospital and Research Institute 54
Early research (Phase 1)Active Not RecruitingNCT02359565
What this trial is testing

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

Who this might be right for
Constitutional Mismatch Repair Deficiency SyndromeLynch SyndromeMalignant Glioma+8 more
National Cancer Institute (NCI) 71
Testing effectiveness (Phase 2)Active Not RecruitingNCT04911621
What this trial is testing

Adjuvant Dendritic Cell Immunotherapy for Pediatric Patients With High-grade Glioma or Diffuse Intrinsic Pontine Glioma

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine Glioma
University Hospital, Antwerp 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT04049669
What this trial is testing

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

Who this might be right for
GlioblastomaMedulloblastomaEpendymoma+1 more
Theodore S. Johnson 130
Early research (Phase 1)Study completedNCT03387020
What this trial is testing

Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors

Who this might be right for
CNS Embryonal Tumor, Not Otherwise SpecifiedMalignant GliomaRecurrent Atypical Teratoid/Rhabdoid Tumor+4 more
Pediatric Brain Tumor Consortium 22
Large-scale testing (Phase 3)UnknownNCT00278278
What this trial is testing

Combination Chemotherapy and Radiation Therapy With or Without Methotrexate in Treating Young Patients With Newly Diagnosed Gliomas

Who this might be right for
Brain and Central Nervous System Tumors
German Society for Pediatric Oncology and Hematology GPOH gGmbH 150