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Results for “Chimera”

1,110 trials

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Showing 20 of 1,110 results

Early research (Phase 1)Active Not RecruitingNCT06895811
What this trial is testing

Clinical Study of Safety and Efficacy of Universal PSMA CAR- T in Refractory CRPC

Who this might be right for
Metastatic Prostate CancerCastration-resistant Prostate CancerMetastatic Castration-resistant Prostate Cancer
Shanghai Changzheng Hospital 3
Testing effectiveness (Phase 2)Looking for participantsNCT07097207
What this trial is testing

Efficacy and Safety of CD19CD20-CAR.p40-T in B-cell Lymphoma

Who this might be right for
Relapsed/Refractory B-cell Lymphoma
Shenzhen University General Hospital 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07832292
What this trial is testing

JNJ-101556143 in Participants With Metastatic Prostate Cancer

Who this might be right for
Prostatic Neoplasms
Janssen Research & Development, LLC 100
Early research (Phase 1)Active Not RecruitingNCT04511871
What this trial is testing

A Phase I Trial of CCT303-406 in Patients With Relapsed or Refractory HER2 Positive Solid Tumors

Who this might be right for
Solid TumorGastric CancerBreast Cancer+2 more
Shanghai PerHum Therapeutics Co., Ltd. 12
Early research (Phase 1)Ended earlyNCT03103971
What this trial is testing

HuJCAR014 CAR-T Cells in Treating Adult Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma or Acute Lymphoblastic Leukemia

Who this might be right for
Recurrent Adult Acute Lymphoblastic LeukemiaRecurrent B-Cell Non-Hodgkin LymphomaRecurrent Diffuse Large B-Cell Lymphoma+14 more
Fred Hutchinson Cancer Center 55
Early research (Phase 1)Looking for participantsNCT07541391
What this trial is testing

Autologous Chimeric Antigen Receptor (CAR) T-cells Targeting the Kappa Myeloma Antigen (KMA) in Kappa Restricted Multiple Myeloma Patients With Relapsed/Refractory Disease

Who this might be right for
Relapsed/Refractory Multiple Myeloma
Peter MacCallum Cancer Centre, Australia 12
Not applicableUnknownNCT06106776
What this trial is testing

CAR-T Cell Induced Cardiac Dysfunction: A Prospective Study

Who this might be right for
Lymphoma
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 48
Early research (Phase 1)Study completedNCT05149391
What this trial is testing

C-CAR039 in Subjects With Relapsed and/or Refractory B Cell Non-Hodgkin's Lymphoma

Who this might be right for
B Cell Non-Hodgkin's Lymphoma
Peking University 3
Early research (Phase 1)Looking for participantsNCT05773040
What this trial is testing

JV-213 Autologous CD79b-targeting Chimeric Antigen Receptor T-cell Therapy in Adults With Relapsed or Refractory B-cell Lymphomas

Who this might be right for
LymphomasB-cell Lymphomas
M.D. Anderson Cancer Center 33
Testing effectiveness (Phase 2)Active Not RecruitingNCT03373097
What this trial is testing

Anti-GD2 CAR T Cells in Pediatric Patients Affected by High Risk and/or Relapsed/Refractory Neuroblastoma or Other GD2-positive Solid Tumors

Who this might be right for
NeuroblastomaNeuroblastoma RecurrentGD2-positive Solid Tumors+3 more
Bambino Gesù Hospital and Research Institute 42
Early research (Phase 1)Active Not RecruitingNCT04049513
What this trial is testing

ENABLE-1 (Engaging Toll-like Receptor Signalling for B-cell Lymphoma Chimeric Antigen Receptor Therapy)

Who this might be right for
Lymphomas Non-Hodgkin's B-CellDiffuse Large B-cell Lymphoma (DLBCL)Primary Mediastinal B-cell Lymphoma (PMBCL)+3 more
Malaghan Institute of Medical Research 30
Early research (Phase 1)Looking for participantsNCT06909474
What this trial is testing

Clinical Trial of CD5-targeted CAR-NK Therapy for Relapse/Refractory T-Cell Hematologic Malignancies

Who this might be right for
T-ALL/Lymphoma
Chongqing Precision Biotech Co., Ltd 15
Testing effectiveness (Phase 2)Looking for participantsNCT06045910
What this trial is testing

A Phase I/II Trial of ALETA-001 for the Treatment of Participants With B-cell Malignancies

Who this might be right for
Lymphoma, Non-HodgkinLymphoma, Large B-Cell, DiffuseLymphoma, Mantle-Cell+3 more
Cancer Research UK 84
Large-scale testing (Phase 3)Study completedNCT00036374
What this trial is testing

The Safety and Effectiveness of Infliximab (Remicade) in Patients With Juvenile Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis, Juvenile
Centocor, Inc. 123
Early research (Phase 1)Looking for participantsNCT06830031
What this trial is testing

Clinical Study of C402-CD19-CAR Treatment in Subjects With Relapsed or Refractory B-cell Lymphoma

Who this might be right for
Diffuse Large B-cell-lymphomaDLBCL, Nos Genetic SubtypesFollicular Lymphoma Grade 3B+3 more
Shanghai Exuma Biotechnology Ltd. 18
Testing effectiveness (Phase 2)Study completedNCT01828021
What this trial is testing

Phase 2 Study of the Monoclonal Antibody MGAH22 (Margetuximab) in Patients With Relapsed or Refractory Advanced Breast Cancer

Who this might be right for
Breast Cancer
MacroGenics 25
Very early researchEnded earlyNCT04034446
What this trial is testing

CD19-CD22 Chimeric Antigen Receptor T (CAR-T) Cell for Treatment of B Cell Acute Lymphoblastic Leukemia (B-ALL)

Who this might be right for
Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia
Institute of Hematology & Blood Diseases Hospital, China 2
Testing effectiveness (Phase 2)Active Not RecruitingNCT02690545
What this trial is testing

Study of CD30 CAR for Relapsed/Refractory CD30+ HL and CD30+ NHL

Who this might be right for
LymphomaLymphoma, Non-HodgkinImmune System Diseases+5 more
UNC Lineberger Comprehensive Cancer Center 38
Early research (Phase 1)Looking for participantsNCT06313957
What this trial is testing

LUCAR-20SP in Subjects With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

Who this might be right for
Relapsed B-cell Non-Hodgkin LymphomaRefractory B-cell Non-Hodgkin Lymphoma
Peking University Cancer Hospital & Institute 42
Early research (Phase 1)Looking for participantsNCT06646627
What this trial is testing

Clinical Trial of Autologous B7-H3 CAR T Cells in Reoccurent Platinum-resistant Ovarian Tumors

Who this might be right for
Ovarian Cancer
Stanford University 48
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