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Results for “Chimera Antigen Receptor (CAR)”

902 trials

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Showing 20 of 902 results

Post-approval studies (Phase 4)UnknownNCT02992834
What this trial is testing

Anti-CD19:TCRζ Chimeric Antigen Receptor-T Cells in the Treatment for CD19+ B Cell Lymphoma

Who this might be right for
Lymphoma, B Cell
jiangjingting 10
Early research (Phase 1)Active Not RecruitingNCT02311621
What this trial is testing

Engineered Neuroblastoma Cellular Immunotherapy (ENCIT)-01

Who this might be right for
NeuroblastomaGanglioneuroblastoma
Seattle Children's Hospital 65
Very early researchWithdrawnNCT06926985
What this trial is testing

An Exploratory Clinical Study of Anti-CD19/BCMA Chimeric Antigen Receptor NK Cell Injection in the Treatment of IgA Nephropathy

Who this might be right for
IgA Nephropathy (IgAN)
Jieyang People's Hospital
Very early researchUnknownNCT04186052
What this trial is testing

Clinical Trial of BCMA CAR T Cell Infusion in Patients With BCMA-positive r/r Multiple Myeloma

Who this might be right for
Multiple Myeloma
PersonGen BioTherapeutics (Suzhou) Co., Ltd. 10
Early research (Phase 1)UnknownNCT03840317
What this trial is testing

Senl_1904A and Senl_1904B Chimeric Antigen Receptor （CAR） T-Cell in the Treatment of r/ r Acute B Lymphocytic Leukemia

Who this might be right for
Acute Lymphocytic Leukemia
Hebei Senlang Biotechnology Inc., Ltd. 20
Testing effectiveness (Phase 2)Study completedNCT01865617
What this trial is testing

Laboratory Treated T Cells in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma, or Acute Lymphoblastic Leukemia

Who this might be right for
CD19-Positive Neoplastic Cells PresentRecurrent Adult Acute Lymphoblastic LeukemiaRecurrent Chronic Lymphocytic Leukemia+10 more
Fred Hutchinson Cancer Center 204
Testing effectiveness (Phase 2)UnknownNCT04082910
What this trial is testing

Metoprolol Treatment for Cytokine Release Syndrome in Patients Treated With Chimeric Antigen Receptor T Cells

Who this might be right for
Solid TumorHematological Malignancy
Chinese PLA General Hospital 30
Early research (Phase 1)Active Not RecruitingNCT02050347
What this trial is testing

Activated T Lymphocytes Expressing CARs, Relapsed CD19+ Malignancies Post-Allo HSCT(CARPASCIO)

Who this might be right for
Non-Hodgkin's LymphomaB-Cell ALLB-Cell CLL
Baylor College of Medicine 7
Early research (Phase 1)Looking for participantsNCT04881240
What this trial is testing

Study of CD19 Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia, in RelapseAcute Lymphoblastic Leukemia, RefractoryPediatric ALL
St. Jude Children's Research Hospital 60
Early research (Phase 1)Looking for participantsNCT06227026
What this trial is testing

Pilot Study of Anti-CD19 Chimeric Antigen Receptor T Cells (CAR-T Cells) for the Treatment of Relapsed/Refractory CD19+ Malignancies

Who this might be right for
Acute Lymphoblastic LeukemiaDiffuse Large B Cell Lymphoma
University of Utah 10
Early research (Phase 1)Looking for participantsNCT05963217
What this trial is testing

Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL

Who this might be right for
Relapsed or Refractory CD19+ B-cell LymphomaRelapsed or Refractory Chronic Lymphocytic LeukemiaRelapsed or Refractory Small Lymphocytic Lymphoma
University Health Network, Toronto 19
Testing effectiveness (Phase 2)UnknownNCT02134262
What this trial is testing

Gene Therapy for B-Cell Non-Hodgkin Lymphoma Using CD19 CAR Gene Transduced T Lymphocytes

Who this might be right for
Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Jichi Medical University 18
Testing effectiveness (Phase 2)Study completedNCT03548207
What this trial is testing

JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-Cell Maturation Antigen (BCMA) in Participants With Relapsed or Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
Janssen Research & Development, LLC 126
Large-scale testing (Phase 3)Active Not RecruitingNCT04181827
What this trial is testing

A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
Janssen Research & Development, LLC 419
Early research (Phase 1)Active Not RecruitingNCT02159495
What this trial is testing

Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm

Who this might be right for
Adult Acute Myeloid Leukemia in RemissionAcute Biphenotypic LeukemiaEarly Relapse of Acute Myeloid Leukemia+10 more
City of Hope Medical Center 31
Early research (Phase 1)Looking for participantsNCT05354375
What this trial is testing

Clinical Study of PSMA-targeted CAR-T Cells in the Treatment of Castration-resistant Prostate Cancer

Who this might be right for
Immunotherapy
The Affiliated Hospital of Xuzhou Medical University 20
Early research (Phase 1)UnknownNCT03093168
What this trial is testing

BCMA Chimeric Antigen Receptor Expressing T Cells in Multiple Myeloma

Who this might be right for
Multiple Myeloma
The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine 10
Not applicableLooking for participantsNCT06989541
What this trial is testing

Immunoglobulin for Hypogammaglobulinemia Due to Chimeric Antigen Receptor T Cell Therapy

Who this might be right for
Hypogammaglobulinemia, Acquired
University of Alberta 30
Early research (Phase 1)Temporarily pausedNCT05993611
What this trial is testing

Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

Who this might be right for
Chronic Graft Versus Host DiseaseHematologic and Lymphocytic DisorderSteroid Refractory Graft Versus Host Disease
City of Hope Medical Center 27
Early research (Phase 1)Looking for participantsNCT07250087
What this trial is testing

Asciminib Maintenance Therapy Following alloHCT or CAR T to Prevent Relapse in Adults With Ph+ALL

Who this might be right for
Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
H. Lee Moffitt Cancer Center and Research Institute 36
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