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Results for “Cholangiocarcinoma With IDH1 Mutation”

12 trials

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Showing 12 of 12 results

Early research (Phase 1)Ended earlyNCT05814536
What this trial is testing

IDH1 Inhibitor AB-218 in Patients With Advanced IDH1 Mutant Cholangiocarcinoma and Other Solid Tumor

Who this might be right for
Cholangiocarcinoma With IDH1 MutationSolid Tumors With IDH1 Mutation
AnHeart Therapeutics Inc. 9
Testing effectiveness (Phase 2)Active Not RecruitingNCT03212274
What this trial is testing

Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations

Who this might be right for
Advanced Malignant Solid NeoplasmGlioblastomaRecurrent Cholangiocarcinoma+4 more
National Cancer Institute (NCI) 89
Early research (Phase 1)Study completedNCT02073994
What this trial is testing

Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 Mutation

Who this might be right for
CholangiocarcinomaChondrosarcomaGlioma+1 more
Institut de Recherches Internationales Servier 174
Testing effectiveness (Phase 2)Ended earlyNCT05921760
What this trial is testing

Ivosidenib, Nivolumab, and Ipilimumab Combination in Previously Treated Subjects With Nonresectable or Metastatic IDH1 Mutant Cholangiocarcinoma

Who this might be right for
IDH1-mutant Cholangiocarcinoma
Servier Bio-Innovation LLC 7
Testing effectiveness (Phase 2)Active Not RecruitingNCT06081829
What this trial is testing

Ivosidenib in Previously Treated Japanese Subjects With Nonresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Who this might be right for
Cholangiocarcinoma Non-resectableCholangiocarcinoma Metastatic
Servier 12
Early research (Phase 1)Active Not RecruitingNCT04521686
What this trial is testing

Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations

Who this might be right for
CholangiocarcinomaChondrosarcomaGlioma+1 more
Eli Lilly and Company 200
Early research (Phase 1)Active Not RecruitingNCT02381886
What this trial is testing

IDH305 in Patients With Advanced Malignancies That Harbor IDH1R132 Mutations

Who this might be right for
Advanced Malignancies That Harbor IDHR132 Mutations
Novartis Pharmaceuticals 166
Large-scale testing (Phase 3)Study completedNCT02989857
What this trial is testing

Study of AG-120 in Previously Treated Advanced Cholangiocarcinoma With IDH1 Mutations (ClarIDHy)

Who this might be right for
Advanced CholangiocarcinomaMetastatic Cholangiocarcinoma
Institut de Recherches Internationales Servier 187
Testing effectiveness (Phase 2)Looking for participantsNCT06501625
What this trial is testing

Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Who this might be right for
Locally Advanced, Unresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation
Institut de Recherches Internationales Servier 52
Testing effectiveness (Phase 2)Study completedNCT03684811
What this trial is testing

FT-2102 in Patients With Advanced Solid Tumors and Gliomas With an IDH1 Mutation

Who this might be right for
Cohort 1a and 1b: Glioma (Advanced Gliomas and Glioblastoma Multiforme)Cohort 2a and 2b: Hepatobiliary Tumors (Hepatocellular Carcinoma, Bile Duct Carcinoma, Intrahepatic Cholangiocarcinoma, Other Hepatobiliary Carcinomas)Cohort 3a and 3b: Chondrosarcoma+2 more
Forma Therapeutics, Inc.
Testing effectiveness (Phase 2)Study completedNCT02496741
What this trial is testing

Metformin And Chloroquine in IDH1/2-mutated Solid Tumors

Who this might be right for
GliomaCholangiocarcinomaChondrosarcoma
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 15
Not applicableLooking for participantsNCT06607302
What this trial is testing

Ivosidenib in Locally Advanced or Metastatic Cholangiocarcinoma With IDH1 R132 Mutation After at Least One Prior Systemic Treatment - an Observational Study

Who this might be right for
Cholangiocarcinoma
iOMEDICO AG 100
93