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Results for “Cholestatic Liver Disease”

51 trials

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Showing 20 of 51 results

Not applicableLooking for participantsNCT03131427
What this trial is testing

China Registry for Genetic / Metabolic Liver Diseases

Who this might be right for
Genetic/Metabolic Liver Diseases
Beijing Friendship Hospital 20,000
Not applicableApproved For MarketingNCT04530994
What this trial is testing

A Maralixibat Expanded Access Program for Patients With Cholestatic Pruritus Associated With Alagille Syndrome (ALGS)

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc.
Testing effectiveness (Phase 2)Ended earlyNCT03995212
What this trial is testing

Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus

Who this might be right for
Cholestatic Pruritus
Cara Therapeutics, Inc. 14
Not applicableStudy completedNCT02922751
What this trial is testing

FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)

Who this might be right for
Biliary AtresiaAlagille SyndromeAlpha1 Anti-Trypsin Deficiency+3 more
Arbor Research Collaborative for Health 552
Testing effectiveness (Phase 2)Ended earlyNCT02360852
What this trial is testing

IBAT Inhibitor A4250 for Cholestatic Pruritus

Who this might be right for
Biliary Cirrhosis, Primary
Sahlgrenska University Hospital 9
Not applicableAvailableNCT05448170
What this trial is testing

Linerixibat Compassionate Use for Cholestatic Pruritus Adult Patients With Primary Biliary Cholangitis (PBC)

Who this might be right for
Pruritus
GlaxoSmithKline
Early research (Phase 1)Looking for participantsNCT06825559
What this trial is testing

Evaluate PK & Safety of Saroglitazar in Subjects With Moderate Hepatic Impairment Due to Cholestatic Liver Disease

Who this might be right for
Cholestatic Liver Disease
Zydus Therapeutics Inc. 6
Testing effectiveness (Phase 2)Study completedNCT00058903
What this trial is testing

Treatment of Cholestatic Pruritus With Sertraline

Who this might be right for
PruritusLiver Cirrhosis, BiliaryHepatitis C
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 40
Large-scale testing (Phase 3)Active Not RecruitingNCT06553768
What this trial is testing

Evaluation of Maralixibat in Pruritus Associated With General Cholestatic Liver Disease (EXPAND)

Who this might be right for
Cholestatic Liver Disease (Except ALGS, PFIC, PBC and PSC)
Mirum Pharmaceuticals, Inc. 90
Testing effectiveness (Phase 2)Study completedNCT02047318
What this trial is testing

An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Subjects With Alagille Syndrome (ALGS)

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 19
Not applicableLooking for participantsNCT06781242
What this trial is testing

Genotype-phenotype Relationship Between Cryptogenic Cholestasis and Familial Intrahepatic Cholestasis

Who this might be right for
Cholestatic Liver DiseaseIntrahepatic CholestasisProgressive Familial Intrahepatic Cholestasis+1 more
IRCCS Azienda Ospedaliero-Universitaria di Bologna 300
Not applicableActive Not RecruitingNCT06604923
What this trial is testing

PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Changes in the Hepatobiliary System in Patients With Primary Biliary Cholangitis Before and After Treatment.

Who this might be right for
Primary Biliary Cholangitis (PBC)CirrhosisCholestasis+2 more
University of Aarhus 30
Testing effectiveness (Phase 2)Study completedNCT04729751
What this trial is testing

Evaluate the Safety and Tolerability of Maralixibat in Infant Participants With Cholestatic Liver Diseases Including Progressive Familial Intrahepatic Cholestasis (PFIC) and Alagille Syndrome (ALGS).

Who this might be right for
Progressive Familial Intrahepatic CholestasisAlagille SyndromeCholestatic Liver Disease
Mirum Pharmaceuticals, Inc. 27
Testing effectiveness (Phase 2)Study completedNCT04168385
What this trial is testing

MRX-800: A Long-Term Safety Study of Maralixibat in the Treatment of Cholestatic Liver Disease in Subjects Who Previously Participated in a Maralixibat Study

Who this might be right for
Cholestatic Liver Disease
Mirum Pharmaceuticals, Inc. 52
Large-scale testing (Phase 3)WithdrawnNCT04531878
What this trial is testing

BSEP Function Rescue During Childhood Inhereditary Cholestatic Diseases

Who this might be right for
Hereditary DiseasesCholestasis, Intrahepatic
Children's Hospital of Fudan University
Early research (Phase 1)Study completedNCT03082937
What this trial is testing

An Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy Subjects

Who this might be right for
Orphan Cholestatic Liver DiseasesProgressive Familial Intrahepatic CholestasisAlagille Syndrome+1 more
Albireo 6
Testing effectiveness (Phase 2)Study completedNCT02057692
What this trial is testing

Evaluation of LUM001 in the Reduction of Pruritus in Alagille Syndrome

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 37
Testing effectiveness (Phase 2)Study completedNCT02117713
What this trial is testing

An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Pediatric Subjects With Alagille Syndrome

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 34
Not applicableLooking for participantsNCT03445585
What this trial is testing

Biobank for Cholestatic Liver Diseases.

Who this might be right for
Primary Sclerosing CholangitisPrimary Biliary CirrhosisCholangiocarcinoma+1 more
Mayo Clinic 9,150
Large-scale testing (Phase 3)Active Not RecruitingNCT04167358
What this trial is testing

Linerixibat Long-term Safety, and Tolerability Study

Who this might be right for
Cholestasis
GlaxoSmithKline 242
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