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Results for “Cholestatic Liver Disease”

52 trials

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Showing 20 of 52 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT05050136
What this trial is testing

Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

Who this might be right for
Primary Biliary CholangitisPBC
Mirum Pharmaceuticals, Inc. 333
Testing effectiveness (Phase 2)Study completedNCT02117713
What this trial is testing

An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Pediatric Subjects With Alagille Syndrome

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 34
Not applicableStudy completedNCT02922751
What this trial is testing

FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)

Who this might be right for
Biliary AtresiaAlagille SyndromeAlpha1 Anti-Trypsin Deficiency+3 more
Arbor Research Collaborative for Health 552
Not applicableLooking for participantsNCT06767605
What this trial is testing

Spanish Registry of Autoimmune and Cholestatic Liver Diseases (ColHai)

Who this might be right for
Hepatitis Autoimmune DiseasePrimary Biliary Cholangitis (PBC)Primary Sclerosing Cholangitis (PSC)+1 more
Asociación Española para el Estudio del Hígado 5,000
Not applicableAvailableNCT05448170
What this trial is testing

Linerixibat Compassionate Use for Cholestatic Pruritus Adult Patients With Primary Biliary Cholangitis (PBC)

Who this might be right for
Pruritus
GlaxoSmithKline
Testing effectiveness (Phase 2)Ended earlyNCT02360852
What this trial is testing

IBAT Inhibitor A4250 for Cholestatic Pruritus

Who this might be right for
Biliary Cirrhosis, Primary
Sahlgrenska University Hospital 9
Large-scale testing (Phase 3)UnknownNCT04787419
What this trial is testing

Probiotics in Pediatric Chronic Cholestasis

Who this might be right for
Cholestatic Liver Disease
Universitas Indonesia 60
Testing effectiveness (Phase 2)Study completedNCT04168385
What this trial is testing

MRX-800: A Long-Term Safety Study of Maralixibat in the Treatment of Cholestatic Liver Disease in Subjects Who Previously Participated in a Maralixibat Study

Who this might be right for
Cholestatic Liver Disease
Mirum Pharmaceuticals, Inc. 52
Testing effectiveness (Phase 2)Ended earlyNCT03995212
What this trial is testing

Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus

Who this might be right for
Cholestatic Pruritus
Cara Therapeutics, Inc. 14
Not applicableWithdrawnNCT05922332
What this trial is testing

Application and Effect Evaluation of Medium Chain Fatty Acid Rich Milk Powder in Infants With Cholestatic Liver Disease

Who this might be right for
Cholestatic Liver Disease
Children's Hospital of Fudan University
Testing effectiveness (Phase 2)Study completedNCT00058903
What this trial is testing

Treatment of Cholestatic Pruritus With Sertraline

Who this might be right for
PruritusLiver Cirrhosis, BiliaryHepatitis C
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 40
Not applicableStudy completedNCT02131623
What this trial is testing

Validation of the Itch Reported Outcome (ItchRO) Diaries in Pediatric Cholestatic Liver Disease

Who this might be right for
Alagille SyndromeProgressive Familial Intrahepatic Cholestasis
Mirum Pharmaceuticals, Inc. 23
Early research (Phase 1)Study completedNCT04469920
What this trial is testing

Hepatic Impairment, Cholestatic Liver Disease, & NASH with Advanced Fibrosis & Normal Hepatic Function

Who this might be right for
Hepatic Impairment
Zydus Therapeutics Inc. 98
Testing effectiveness (Phase 2)UnknownNCT06019936
What this trial is testing

A Randomized,Double-blind, Placebo Controlled, Multicenter Study to Evaluate the Safety and Efficacy of MT2004 Capsule in DILI Subjects

Who this might be right for
Drug-Induced Liver InjuryCholestatic Liver InjuryMixed Liver Injury
Xi'An Aolitai Pharmaceutical Technology Co Ltd 80
Early research (Phase 1)Study completedNCT01088607
What this trial is testing

Safety and Efficacy Study of Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing Cholangitis

Who this might be right for
Primary Sclerosing Cholangitis
University of Tennessee 27
Not applicableStudy completedNCT01161992
What this trial is testing

Genomics of Primary Sclerosing Cholangitis (PSC)

Who this might be right for
Primary Sclerosing Cholangitis (PSC)
Mayo Clinic 1,500
Post-approval studies (Phase 4)Looking for participantsNCT07670611
What this trial is testing

Vitamin D2 vs Vitamin D2 Plus Calcitriol in Cholestatic Children With Vitamin D Deficiency

Who this might be right for
Cholestatic Liver DiseaseChronic Liver Disease (CLD)Vitamin D Deficiency+1 more
Chulalongkorn University 54
Not applicableApproved For MarketingNCT04530994
What this trial is testing

A Maralixibat Expanded Access Program for Patients With Cholestatic Pruritus Associated With Alagille Syndrome (ALGS)

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc.
Not applicableActive Not RecruitingNCT06604923
What this trial is testing

PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Changes in the Hepatobiliary System in Patients With Primary Biliary Cholangitis Before and After Treatment.

Who this might be right for
Primary Biliary Cholangitis (PBC)CirrhosisCholestasis+2 more
University of Aarhus 30
Large-scale testing (Phase 3)Study completedNCT00756171
What this trial is testing

Colesevelam Versus Placebo in Cholestatic Pruritus

Who this might be right for
Chronic Liver Disease
Foundation for Liver Research 38
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