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Results for “Cholestatic Liver Disease”

51 trials

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Showing 20 of 51 results

Early research (Phase 1)Looking for participantsNCT06825559
What this trial is testing

Evaluate PK & Safety of Saroglitazar in Subjects With Moderate Hepatic Impairment Due to Cholestatic Liver Disease

Who this might be right for
Cholestatic Liver Disease
Zydus Therapeutics Inc. 6
Testing effectiveness (Phase 2)Ended earlyNCT02360852
What this trial is testing

IBAT Inhibitor A4250 for Cholestatic Pruritus

Who this might be right for
Biliary Cirrhosis, Primary
Sahlgrenska University Hospital 9
Testing effectiveness (Phase 2)Study completedNCT04729751
What this trial is testing

Evaluate the Safety and Tolerability of Maralixibat in Infant Participants With Cholestatic Liver Diseases Including Progressive Familial Intrahepatic Cholestasis (PFIC) and Alagille Syndrome (ALGS).

Who this might be right for
Progressive Familial Intrahepatic CholestasisAlagille SyndromeCholestatic Liver Disease
Mirum Pharmaceuticals, Inc. 27
Testing effectiveness (Phase 2)Study completedNCT02047318
What this trial is testing

An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Subjects With Alagille Syndrome (ALGS)

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 19
Early research (Phase 1)Study completedNCT01088607
What this trial is testing

Safety and Efficacy Study of Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing Cholangitis

Who this might be right for
Primary Sclerosing Cholangitis
University of Tennessee 27
Not applicableStudy completedNCT01556412
What this trial is testing

Endoscopic Ultrasound as an Early Diagnostic Tool for Primary Sclerosing Cholangitis

Who this might be right for
Primary Sclerosing Cholangitis
Tischendorf, Jens, M.D. 32
Not applicableActive Not RecruitingNCT06604923
What this trial is testing

PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Changes in the Hepatobiliary System in Patients With Primary Biliary Cholangitis Before and After Treatment.

Who this might be right for
Primary Biliary Cholangitis (PBC)CirrhosisCholestasis+2 more
University of Aarhus 30
Not applicableLooking for participantsNCT06767605
What this trial is testing

Spanish Registry of Autoimmune and Cholestatic Liver Diseases (ColHai)

Who this might be right for
Hepatitis Autoimmune DiseasePrimary Biliary Cholangitis (PBC)Primary Sclerosing Cholangitis (PSC)+1 more
Asociación Española para el Estudio del Hígado 5,000
Testing effectiveness (Phase 2)Study completedNCT05525520
What this trial is testing

Study to Evaluate EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing Cholangitis

Who this might be right for
Pruritus
Escient Pharmaceuticals, Inc 62
Not applicableLooking for participantsNCT03445585
What this trial is testing

Biobank for Cholestatic Liver Diseases.

Who this might be right for
Primary Sclerosing CholangitisPrimary Biliary CirrhosisCholangiocarcinoma+1 more
Mayo Clinic 9,150
Not applicableStudy completedNCT01161953
What this trial is testing

Genetic Epidemiology of Primary Biliary Cirrhosis (PBC)

Who this might be right for
Primary Biliary Cirrhosis
Mayo Clinic 1,500
Early research (Phase 1)Looking for participantsNCT05045482
What this trial is testing

Hepatic Impairment With Cirrhosis Due to Cholestatic Liver Disease

Who this might be right for
Hepatic ImpairmentCirrhosisCholestatic Liver Disease
Zydus Therapeutics Inc. 30
Not applicableAvailableNCT05448170
What this trial is testing

Linerixibat Compassionate Use for Cholestatic Pruritus Adult Patients With Primary Biliary Cholangitis (PBC)

Who this might be right for
Pruritus
GlaxoSmithKline
Large-scale testing (Phase 3)Looking for participantsNCT06553768
What this trial is testing

Evaluation of Maralixibat in Pruritus Associated With General Cholestatic Liver Disease (EXPAND)

Who this might be right for
Cholestatic Liver Disease (Except ALGS, PFIC, PBC and PSC)
Mirum Pharmaceuticals, Inc. 90
Not applicableLooking for participantsNCT03131427
What this trial is testing

China Registry for Genetic / Metabolic Liver Diseases

Who this might be right for
Genetic/Metabolic Liver Diseases
Beijing Friendship Hospital 20,000
Large-scale testing (Phase 3)Active Not RecruitingNCT04167358
What this trial is testing

Linerixibat Long-term Safety, and Tolerability Study

Who this might be right for
Cholestasis
GlaxoSmithKline 245
Testing effectiveness (Phase 2)Study completedNCT01903460
What this trial is testing

Safety and Efficacy Study of LUM001 in the Treatment of Cholestatic Liver Disease in Patients With Alagille Syndrome

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 20
Testing effectiveness (Phase 2)Study completedNCT02057692
What this trial is testing

Evaluation of LUM001 in the Reduction of Pruritus in Alagille Syndrome

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 37
Not applicableTemporarily pausedNCT00571272
What this trial is testing

Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC)

Who this might be right for
Liver DiseasesAlagille SyndromeAlpha 1-Antitrypsin Deficiency
Arbor Research Collaborative for Health 1,675
Not applicableWithdrawnNCT05922332
What this trial is testing

Application and Effect Evaluation of Medium Chain Fatty Acid Rich Milk Powder in Infants With Cholestatic Liver Disease

Who this might be right for
Cholestatic Liver Disease
Children's Hospital of Fudan University
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