Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Cholestatic Pruritus”

18 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 18 of 18 results

Early research (Phase 1)Study completedNCT04510090
What this trial is testing

Evaluate the Safety, Tolerability, and PK of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic Pruritus

Who this might be right for
PruritusCholestasisKidney Failure
Escient Pharmaceuticals, Inc 89
Not applicableApproved For MarketingNCT04530994
What this trial is testing

A Maralixibat Expanded Access Program for Patients With Cholestatic Pruritus Associated With Alagille Syndrome (ALGS)

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc.
Testing effectiveness (Phase 2)Ended earlyNCT03995212
What this trial is testing

Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus

Who this might be right for
Cholestatic Pruritus
Cara Therapeutics, Inc. 14
Testing effectiveness (Phase 2)Ended earlyNCT02360852
What this trial is testing

IBAT Inhibitor A4250 for Cholestatic Pruritus

Who this might be right for
Biliary Cirrhosis, Primary
Sahlgrenska University Hospital 9
Not applicableAvailableNCT05448170
What this trial is testing

Linerixibat Compassionate Use for Cholestatic Pruritus Adult Patients With Primary Biliary Cholangitis (PBC)

Who this might be right for
Pruritus
GlaxoSmithKline
Testing effectiveness (Phase 2)Study completedNCT00058903
What this trial is testing

Treatment of Cholestatic Pruritus With Sertraline

Who this might be right for
PruritusLiver Cirrhosis, BiliaryHepatitis C
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 40
Large-scale testing (Phase 3)Active Not RecruitingNCT06553768
What this trial is testing

Evaluation of Maralixibat in Pruritus Associated With General Cholestatic Liver Disease (EXPAND)

Who this might be right for
Cholestatic Liver Disease (Except ALGS, PFIC, PBC and PSC)
Mirum Pharmaceuticals, Inc. 90
Testing effectiveness (Phase 2)Study completedNCT02057692
What this trial is testing

Evaluation of LUM001 in the Reduction of Pruritus in Alagille Syndrome

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 37
Large-scale testing (Phase 3)Active Not RecruitingNCT04167358
What this trial is testing

Linerixibat Long-term Safety, and Tolerability Study

Who this might be right for
Cholestasis
GlaxoSmithKline 242
Not applicableStudy completedNCT02131623
What this trial is testing

Validation of the Itch Reported Outcome (ItchRO) Diaries in Pediatric Cholestatic Liver Disease

Who this might be right for
Alagille SyndromeProgressive Familial Intrahepatic Cholestasis
Mirum Pharmaceuticals, Inc. 23
Testing effectiveness (Phase 2)Active Not RecruitingNCT04663308
What this trial is testing

Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Sclerosing Cholangitis (PSC)

Who this might be right for
Primary Sclerosing Cholangitis
Mirum Pharmaceuticals, Inc. 182
Large-scale testing (Phase 3)UnknownNCT02701166
What this trial is testing

The Effect of Bezafibrate on Cholestatic Itch

Who this might be right for
Primary Biliary CholangitisPrimary Sclerosing CholangitisSecondary Sclerosing Cholangitis
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 84
Testing effectiveness (Phase 2)Looking for participantsNCT05050136
What this trial is testing

Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

Who this might be right for
Primary Biliary CholangitisPBC
Mirum Pharmaceuticals, Inc. 260
Large-scale testing (Phase 3)Study completedNCT00756171
What this trial is testing

Colesevelam Versus Placebo in Cholestatic Pruritus

Who this might be right for
Chronic Liver Disease
Foundation for Liver Research 38
Large-scale testing (Phase 3)Study completedNCT04950127
What this trial is testing

Global Linerixibat Itch Study of Efficacy and Safety in Primary Biliary Cholangitis (PBC) (GLISTEN)

Who this might be right for
Pruritus
GlaxoSmithKline 238
Testing effectiveness (Phase 2)Study completedNCT05525520
What this trial is testing

Study to Evaluate EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing Cholangitis

Who this might be right for
Pruritus
Escient Pharmaceuticals, Inc 62
Testing effectiveness (Phase 2)Study completedNCT02630875
What this trial is testing

A4250, an IBAT Inhibitor in Pediatric Cholestasis

Who this might be right for
Pediatric Cholestasis
Albireo 24
Testing effectiveness (Phase 2)Study completedNCT02057718
What this trial is testing

Open Label Study to Evaluate Efficacy and Long Term Safety of LUM001 (Maralixibat) in the Treatment of Cholestatic Liver Disease in Patients With Progressive Familial Intrahepatic Cholestasis

Who this might be right for
Progressive Familial Intrahepatic Cholestasis (PFIC)
Mirum Pharmaceuticals, Inc. 33