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Results for “Chromosome Deletion”

108 trials

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Showing 20 of 108 results

Testing effectiveness (Phase 2)Study completedNCT05630066
What this trial is testing

Investigate the Pharmacokinetics (PK) and Safety and to Provide Proof of Mechanism of Alogabat in Children and Adolescents Aged 5-17 Years With Angelman Syndrome (AS) With Deletion Genotype.

Who this might be right for
Angelman Syndrome
Hoffmann-La Roche 48
Large-scale testing (Phase 3)Study completedNCT02756611
What this trial is testing

Evaluate the Efficacy of Venetoclax Monotherapy in Relapsed/Refractory Participants With Chronic Lymphocytic Leukemia (CLL)

Who this might be right for
Chronic Lymphocytic Leukemia
AbbVie 258
Not applicableStudy completedNCT00445744
What this trial is testing

Cyclophosphamide and Busulfan Followed by Donor Stem Cell Transplant in Treating Patients With Myelofibrosis, Acute Myeloid Leukemia, or Myelodysplastic Syndrome

Who this might be right for
Adult Acute Myeloid Leukemia in RemissionAdult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)+19 more
Fred Hutchinson Cancer Center 52
Not applicableEnrolling By InvitationNCT03836300
What this trial is testing

Parent and Infant Inter(X)Action Intervention (PIXI)

Who this might be right for
Fragile X SyndromeAngelman SyndromePrader-Willi Syndrome+11 more
RTI International 120
Not applicableStudy completedNCT04141540
What this trial is testing

Molecular Variants Associated With Schizophrenia: Differential Analysis of Monozygotic Twins With Variable Phenotypic 22q11

Who this might be right for
Di George Syndrome
Hôpital le Vinatier 2
Not applicableStudy completedNCT01220531
What this trial is testing

Thymus Transplantation Safety-Efficacy

Who this might be right for
Complete DiGeorge AnomalyDiGeorge SyndromeDiGeorge Anomaly+1 more
Sumitomo Pharma Switzerland GmbH 29
Testing effectiveness (Phase 2)Study completedNCT05149898
What this trial is testing

Open-Label Study of ZYN002 Administered as a Transdermal Gel to Children and Adolescents With 22q11.2 Deletion Syndrome (INSPIRE)

Who this might be right for
22Q11.2 Deletion Syndrome
Harmony Biosciences Management, Inc. 20
Testing effectiveness (Phase 2)Looking for participantsNCT07284641
What this trial is testing

Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)

Who this might be right for
Common Variable Immunodeficiency (CVID)Primary Immune Regulatory DisorderImmune Dysregulation+12 more
Paul Szabolcs 25
Not applicableLooking for participantsNCT04869683
What this trial is testing

Biocollection in MyeloDysplastic Syndrome (P-MDS)

Who this might be right for
Myelodysplastic SyndromesMyelodysplastic AnemiaMyelodysplastic Syndrome With Isolated Del(5Q)+3 more
University Hospital, Brest 150
Not applicableStudy completedNCT01647295
What this trial is testing

Social Interactions: Ocular Explorations and Pupillometry in Autism

Who this might be right for
Autism Spectrum Disorders
Institut National de la Santé Et de la Recherche Médicale, France 150
Testing effectiveness (Phase 2)Study completedNCT01527045
What this trial is testing

Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies

Who this might be right for
Aggressive Non-Hodgkin LymphomaBlasts Under 5 Percent of Bone Marrow Nucleated CellsChronic Lymphocytic Leukemia+18 more
Fred Hutchinson Cancer Center 47
Testing effectiveness (Phase 2)WithdrawnNCT03943342
What this trial is testing

Ibrutinib and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia After Ibrutinib Resistance

Who this might be right for
Chronic Lymphocytic LeukemiaLoss of Chromosome 17p
Kerry Rogers
Not applicableStudy completedNCT01781923
What this trial is testing

Cognitive Remediation in 22q11DS

Who this might be right for
22q11.2 Deletion SyndromeVelo-Cardio-Facial Syndrome
Duke University 38
Early research (Phase 1)Study completedNCT00506259
What this trial is testing

Treatment Strategies for Children With Smith-Magenis Syndrome

Who this might be right for
Developmental Delay DisordersChromosome DeletionMental Retardation+2 more
National Human Genome Research Institute (NHGRI) 23
Testing effectiveness (Phase 2)Study completedNCT02666950
What this trial is testing

WEE1 Inhibitor AZD1775 With or Without Cytarabine in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome

Who this might be right for
Chronic Myelomonocytic LeukemiaMyelodysplastic Syndrome With Isolated Del(5q)Myelodysplastic/Myeloproliferative Neoplasm+3 more
Mayo Clinic 3
Not applicableEnded earlyNCT00267397
What this trial is testing

Prevalence and Clinical Spectrum of the 22q11 Deletion

Who this might be right for
Congenital Disorders
Children's Healthcare of Atlanta
Large-scale testing (Phase 3)Looking for participantsNCT07342478
What this trial is testing

ROCKET-CLL Global Phase 3 Study: Rocbrutinib vs Pirtobrutinib in cBTKi-Pretreated R/R CLL/SLL

Who this might be right for
CLL / SLLCLL (Chronic Lymphocytic Leukemia)CLL, Refractory+5 more
Newave Pharmaceutical Inc 306
Testing effectiveness (Phase 2)Study completedNCT01789255
What this trial is testing

Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Myeloid Leukemia in RemissionAdult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities+115 more
National Cancer Institute (NCI) 12
Not applicableEnded earlyNCT03284060
What this trial is testing

Social Cognition Training and Cognitive Remediation

Who this might be right for
22q11.2 Deletion Syndrome
Hôpital le Vinatier 3
Not applicableEnded earlyNCT01010256
What this trial is testing

The Expression of PTEN Protein and mRNA in Malignant Cells of Chronic Myelomonocytic Leukemia

Who this might be right for
Chronic Myelomonocytic Leukemia
University of Arkansas 4
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