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Results for “Chromosome Deletion”

107 trials

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Showing 20 of 107 results

Testing effectiveness (Phase 2)Study completedNCT05149898
What this trial is testing

Open-Label Study of ZYN002 Administered as a Transdermal Gel to Children and Adolescents With 22q11.2 Deletion Syndrome (INSPIRE)

Who this might be right for
22Q11.2 Deletion Syndrome
Harmony Biosciences Management, Inc. 20
Not applicableStudy completedNCT02000167
What this trial is testing

Mitochondrial Dysfunction in Phelan-McDermid Syndrome

Who this might be right for
Phelan-McDermid Syndrome
University of Arkansas 51
Not applicableStudy completedNCT02541058
What this trial is testing

Non-Invasive Chromosomal Evaluation of 22q11.2

Who this might be right for
22q.11.2 Deletion/Duplication
Cindy Cisneros 420
Early research (Phase 1)Study completedNCT01163357
What this trial is testing

Bortezomib, Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant For High-Risk Stage I or II Multiple Myeloma

Who this might be right for
Autologous Hematopoietic Stem Cell Transplant RecipientLoss of Chromosome 17pPlasma Cell Leukemia+2 more
City of Hope Medical Center 18
Not applicableLooking for participantsNCT05664412
What this trial is testing

Using Transcranial Alternating Current Stimulation to Improve Executive Function in 22q11.2 Deletion Syndrome

Who this might be right for
22Q11 Deletion SyndrometACS
Stephan Eliez 40
Testing effectiveness (Phase 2)Study completedNCT01527045
What this trial is testing

Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies

Who this might be right for
Aggressive Non-Hodgkin LymphomaBlasts Under 5 Percent of Bone Marrow Nucleated CellsChronic Lymphocytic Leukemia+18 more
Fred Hutchinson Cancer Center 47
Testing effectiveness (Phase 2)UnknownNCT00885508
What this trial is testing

The Efficacy and Safety of Lenalidomide Combined to Escalating Doses of Chemotherapy in Intermediate-2-or High Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) With Del 5q

Who this might be right for
Myelodysplastic SyndromeChronic Myelomonocytic LeukemiaAcute Myeloid Leukemia
Groupe Francophone des Myelodysplasies 85
Testing effectiveness (Phase 2)Active Not RecruitingNCT01821781
What this trial is testing

Immune Disorder HSCT Protocol

Who this might be right for
Immune Deficiency DisordersSevere Combined ImmunodeficiencyChronic Granulomatous Disease+11 more
Washington University School of Medicine 20
Large-scale testing (Phase 3)Ended earlyNCT00395538
What this trial is testing

Effects of PTH Replacement on Bone in Hypoparathyroidism

Who this might be right for
HypoparathyroidismDiGeorge Syndrome
National Institute of Dental and Craniofacial Research (NIDCR) 46
Testing effectiveness (Phase 2)Ended earlyNCT00699842
What this trial is testing

A Dose Range Finding Study of Lenalidomide in Non-5q Chromosome Deletion in Low and Intermediate Risk Myelodysplastic Syndrome (MDS) Patients

Who this might be right for
Myelodysplastic SyndromeMDSLow to Intermediate-1 MDS+1 more
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 8
Testing effectiveness (Phase 2)Looking for participantsNCT07284641
What this trial is testing

Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)

Who this might be right for
Common Variable Immunodeficiency (CVID)Primary Immune Regulatory DisorderImmune Dysregulation+12 more
Paul Szabolcs 25
Testing effectiveness (Phase 2)Study completedNCT01008462
What this trial is testing

Autologous Peripheral Blood Stem Cell Transplant Followed by Donor Bone Marrow Transplant in Treating Patients With High-Risk Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia

Who this might be right for
B-Cell Prolymphocytic LeukemiaHypodiploidyLoss of Chromosome 17p+18 more
Fred Hutchinson Cancer Center 16
Not applicableEnded earlyNCT02527954
What this trial is testing

Aneuploidies in Embryos and Spermatozoa From Patients With Y-chromosome Microdeletions

Who this might be right for
Male Sterility Due to Y-chromosome Deletions
Instituto Valenciano de Infertilidad, IVI Alicante 5
Early research (Phase 1)Study completedNCT02895906
What this trial is testing

Safety and Efficacy Study of NFC-1 in Subjects Aged 12-17 Years With 22q11.2DS & Associated Neuropsychiatric Conditions

Who this might be right for
22q11.2 Deletion Syndrome
Aevi Genomic Medicine, LLC, a Cerecor company 2
Not applicableEnded earlyNCT00278005
What this trial is testing

Infection in DiGeorge Following CHD Surgery

Who this might be right for
DiGeorge SyndromeCongenital Heart Defects
Children's Healthcare of Atlanta 400
Testing effectiveness (Phase 2)Study completedNCT02337829
What this trial is testing

Acalabrutinib in Patients With Relapsed/Refractory and Treatment naïve Deletion 17p CLL/SLL

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
Acerta Pharma BV 48
Testing effectiveness (Phase 2)Study completedNCT05630066
What this trial is testing

Investigate the Pharmacokinetics (PK) and Safety and to Provide Proof of Mechanism of Alogabat in Children and Adolescents Aged 5-17 Years With Angelman Syndrome (AS) With Deletion Genotype.

Who this might be right for
Angelman Syndrome
Hoffmann-La Roche 48
Not applicableStudy completedNCT00105274
What this trial is testing

Velocardiofacial (VCFS; 22q11.2; DiGeorge) Syndrome Study

Who this might be right for
DiGeorge SyndromeVelocardiofacial Syndrome22q11.2 Syndrome
National Institute of Mental Health (NIMH)
Testing effectiveness (Phase 2)Study completedNCT01789255
What this trial is testing

Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Myeloid Leukemia in RemissionAdult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities+115 more
National Cancer Institute (NCI) 12
Not applicableStudy completedNCT05849441
What this trial is testing

Mindfulness Program for Adolescents With 22q11DS

Who this might be right for
22Q11 Deletion Syndrome
Innovation Research & Training 110
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