Not applicableUnknownNCT06545305What this trial is testingIncidence and Risk Factors of Ocular Complications Among Patients With HomocystinuriaWho this might be right forComplications King Fahad Armed Forces Hospital 6
Not applicableStudy completedNCT04021732What this trial is testingEffects of Exercise on Metabolic Parameters in Classical HomocystinuriaWho this might be right forHomocystinuria University of Lausanne 12
Testing effectiveness (Phase 2)Looking for participantsNCT03406611What this trial is testingPegtibatinase as a Treatment for Patients With Classical Homocystinuria (HCU) (Also Known as the COMPOSE Study)Who this might be right forHomocystinuria Travere Therapeutics, Inc. 39
Not applicableUnknownNCT06622577What this trial is testingThe Effect of Dietary Management and Cysteine Supplementation on Growth Parameters and Biochemical Control for Pediatric Qatari Patients Affected with Classical B6 Non-responsive Homocystinuria.Who this might be right forClassical Homocystinuria Hamad Medical Corporation 50
Testing effectiveness (Phase 2)Temporarily pausedNCT04015557What this trial is testingEffect of Acetaminophen and N-Acetylcysteine on Liver Metabolism on HomocystinuriaWho this might be right forCBS Deficiency Hospital de Clinicas de Porto Alegre 10
Large-scale testing (Phase 3)Looking for participantsNCT06247085What this trial is testingInvestigate Efficacy and Safety of Pegtibatinase Compared With Placebo in Participants ≥12 to ≤65 Years of Age With Classical Homocystinuria (HCU) Due to Cystathionine Beta Synthase Deficiency Receiving Standard of Care TreatmentWho this might be right forHomocystinuria Travere Therapeutics, Inc. 70
Large-scale testing (Phase 3)Enrolling By InvitationNCT06431893What this trial is testingA Long-term Extension Study to Assess the Long-term Safety and Efficacy of Pegtibatinase Treatment in Participants ≥5 to ≤65 Years of Age With Classical Homocystinuria (HCU) (ENSEMBLE)Who this might be right forHomocystinuria Travere Therapeutics, Inc. 100
Not applicableLooking for participantsNCT06556615What this trial is testingHealth Related Quality of Life (HrQoL) in Classical Homocystinuria (CBS Deficiency)Who this might be right forHomocystinuria University Children's Hospital, Zurich 80