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Results for “Clinical Stage III Gastroesophageal Junction Adenocarcinoma”

61 trials

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Showing 20 of 61 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT07068516
What this trial is testing

Perioperative Tislelizumab Plus Chemotherapy Versus Chemotherapy Alone in MHC-II-Positive Gastric/GEJ Cancer

Who this might be right for
Gastric Cancer Stage
Xiangdong Cheng 470
Large-scale testing (Phase 3)Looking for participantsNCT03801876
What this trial is testing

Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

Who this might be right for
Clinical Stage I Esophageal Adenocarcinoma AJCC v8Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8+10 more
NRG Oncology 300
Large-scale testing (Phase 3)Study completedNCT00680901
What this trial is testing

LOGiC - Lapatinib Optimization Study in ErbB2 (HER2) Positive Gastric Cancer: A Phase III Global, Blinded Study Designed to Evaluate Clinical Endpoints and Safety of Chemotherapy Plus Lapatinib

Who this might be right for
Neoplasms, Gastrointestinal Tract
Novartis Pharmaceuticals 545
Testing effectiveness (Phase 2)Study completedNCT04097028
What this trial is testing

Use of Trifluridine/Tipiracil and Oxaliplatin as Induction Chemotherapy for the Treatment of Resectable Esophageal or Gastroesophageal Junction (GEJ) Adenocarcinoma

Who this might be right for
Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8Clinical Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage III Esophageal Adenocarcinoma AJCC v8+13 more
Roswell Park Cancer Institute 22
Large-scale testing (Phase 3)Looking for participantsNCT07023315
What this trial is testing

A Phase III Clinical Study of Cadonilimab Plus SOX as Perioperative Treatment for Patients With Resectable G/GEJ Adenocarcinoma

Who this might be right for
Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma
Akeso 760
Testing effectiveness (Phase 2)Looking for participantsNCT05651594
What this trial is testing

Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Clinical Stage II Esophageal Adenocarcinoma AJCC v8Clinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+8 more
Roswell Park Cancer Institute
Testing effectiveness (Phase 2)UnknownNCT04660760
What this trial is testing

Ramucirumab and Trifluridine/Tipiracil or Paclitaxel for the Treatment of Patients With Previously Treated Advanced Gastric or Gastroesophageal Junction Cancer

Who this might be right for
Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IV Gastric Cancer AJCC v8+28 more
Academic and Community Cancer Research United 116
Testing effectiveness (Phase 2)Looking for participantsNCT06265285
What this trial is testing

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Who this might be right for
Advanced Esophageal Squamous Cell CarcinomaAdvanced Renal Cell CarcinomaClinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8+28 more
Mayo Clinic 50
Not applicableNot Yet RecruitingNCT07439484
What this trial is testing

Individually Tailored, Supervised, Remote Exercise Intervention to Improve Physical Function for Stage I-III Gastroesophageal Cancer Survivors, PRECISE Trial

Who this might be right for
Clinical Stage I Esophageal Adenocarcinoma American Joint Committee on Cancer (AJCC) v8Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8Clinical Stage I Gastric Cancer AJCC v8+9 more
Jonsson Comprehensive Cancer Center
Large-scale testing (Phase 3)Study completedNCT03221426
What this trial is testing

Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants With Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-585/KEYNOTE-585)

Who this might be right for
Gastric CancerGastroesophageal Junction Cancer
Merck Sharp & Dohme LLC 1,007
Testing effectiveness (Phase 2)Looking for participantsNCT07277439
What this trial is testing

Phase II Trial of Neoadjuvant Thymalfasin, PD-1 Inhibitor, and Chemoradiotherapy for cStage III GEJ Adenocarcinoma

Who this might be right for
Gastric Cancer
The First Affiliated Hospital with Nanjing Medical University 48
Early research (Phase 1)Active Not RecruitingNCT04522336
What this trial is testing

Pembrolizumab and Chemoradiotherapy for the Treatment of Unresectable Gastroesophageal Cancer

Who this might be right for
Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8+16 more
M.D. Anderson Cancer Center
Large-scale testing (Phase 3)Temporarily pausedNCT03604991
What this trial is testing

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

Who this might be right for
Clinical Stage II Esophageal Adenocarcinoma AJCC v8Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage III Esophageal Adenocarcinoma AJCC v8+5 more
National Cancer Institute (NCI) 278
Early research (Phase 1)Active Not RecruitingNCT04704661
What this trial is testing

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

Who this might be right for
Advanced Breast CarcinomaAdvanced Colon CarcinomaAdvanced Colorectal Carcinoma+37 more
National Cancer Institute (NCI) 51
Testing effectiveness (Phase 2)Looking for participantsNCT05269381
What this trial is testing

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+97 more
Mayo Clinic 132
Testing effectiveness (Phase 2)Looking for participantsNCT06461910
What this trial is testing

Efficacy and Safety of Anti-PD-1, Thymalfasin, and SOX in Neoadjuvant Treatment of cStage III Gastric/Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric CancerEsophagogastric Junction Adenocarcinoma
Zekuan Xu 30
Not applicableStudy completedNCT03707574
What this trial is testing

Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study

Who this might be right for
Advanced Malignant NeoplasmAdvanced MelanomaAdvanced Renal Cell Carcinoma+51 more
National Cancer Institute (NCI) 64
Early research (Phase 1)WithdrawnNCT05296005
What this trial is testing

Neoadjuvant Therapy for the Treatment of Gastroesophageal Junction and Gastric Cancers

Who this might be right for
Clinical Stage I Gastric Cancer AJCC v8Clinical Stage II Gastric Cancer AJCC v8Clinical Stage IIA Gastric Cancer AJCC v8+22 more
Ohio State University Comprehensive Cancer Center
Not applicableActive Not RecruitingNCT04314401
What this trial is testing

National Cancer Institute "Cancer Moonshot Biobank"

Who this might be right for
Acute Myeloid LeukemiaAnatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8+26 more
National Cancer Institute (NCI) 1,600
Testing effectiveness (Phase 2)Looking for participantsNCT06078709
What this trial is testing

Preoperative Hypofractionated Radiotherapy With FOLFOX for Esophageal or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Clinical Stage I Esophageal Adenocarcinoma AJCC v8Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage II Esophageal Adenocarcinoma AJCC v8+3 more
Mayo Clinic 99
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