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Results for “Clonal Myeloid Neoplasm”

22 trials

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Showing 20 of 22 results

Large-scale testing (Phase 3)Active Not RecruitingNCT05456191
What this trial is testing

Investigate Tolerability and Efficacy of Asciminib (Oral) Versus Nilotinib (Oral) in Adult Participants (≥18 Years of Age) With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP)

Who this might be right for
Philadelphia Chromosome-Positive Chronic Myeloid Leukemia
Novartis Pharmaceuticals 568
Not applicableLooking for participantsNCT07143669
What this trial is testing

Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations

Who this might be right for
Clonal Mast Cell DiseaseKIT D816V MutationSuspected KITD816V Mutated Clonal Mast Cell Disease
Blueprint Medicines Corporation 450
Testing effectiveness (Phase 2)Study completedNCT01807598
What this trial is testing

Brentuximab Vedotin in Treating Patients With Advanced Systemic Mastocytosis or Mast Cell Leukemia

Who this might be right for
Aggressive Systemic MastocytosisMast Cell LeukemiaSystemic Mastocytosis
Jason Robert Gotlib 10
Large-scale testing (Phase 3)Active Not RecruitingNCT04948333
What this trial is testing

Asciminib Treatment Optimization in ≥ 3rd Line CML-CP

Who this might be right for
Chronic Myelogenous Leukemia
Novartis Pharmaceuticals 199
Not applicableNot Yet RecruitingNCT05969821
What this trial is testing

Clonal Hematopoiesis of Immunological Significance

Who this might be right for
Immune System DiseasesAutoimmune DiseasesInflammation+13 more
Assistance Publique - Hôpitaux de Paris 1,000
Not applicableStudy completedNCT00899795
What this trial is testing

Evaluating Cell Damage in Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, or Fanconi Anemia; in Patients Who Were Exposed to Alkylating Agents; and in Healthy Volunteers

Who this might be right for
LeukemiaMyelodysplastic Syndromes
OHSU Knight Cancer Institute 35
Large-scale testing (Phase 3)Study completedNCT03106779
What this trial is testing

Study of Efficacy of CML-CP Patients Treated With ABL001 Versus Bosutinib, Previously Treated With 2 or More TKIs

Who this might be right for
Chronic Myelogenous Leukemia
Novartis Pharmaceuticals 233
Not applicableLooking for participantsNCT05983991
What this trial is testing

Study for Characterisation of Predictive Parameters of Clonal Evolution in Subjects With GATA2 Germline Mutation

Who this might be right for
GATA2 Gene Mutation
Institut Claudius Regaud 150
Testing effectiveness (Phase 2)Looking for participantsNCT03418038
What this trial is testing

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

Who this might be right for
Clonal Cytopenia of Undetermined SignificanceHigh Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 RearrangementsRecurrent Diffuse Large B-Cell Lymphoma+5 more
Mayo Clinic 80
Not applicableActive Not RecruitingNCT03682029
What this trial is testing

Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies

Who this might be right for
Myelodysplastic SyndromesChronic Myelomonocytic Leukemia-1Cytopenia
Rigshospitalet, Denmark 109
Not applicableActive Not RecruitingNCT04902833
What this trial is testing

Acquired Pyruvate Kinase Deficiency In Clonal Myeloid Neoplasms

Who this might be right for
Pyruvate Kinase DeficiencyPyruvate Kinase Deficiency AnemiaHereditary Hemolytic Anemia+8 more
Massachusetts General Hospital 100
Not applicableLooking for participantsNCT02958462
What this trial is testing

Pre-myeloid Cancer and Bone Marrow Failure Clinic Study

Who this might be right for
Myeloid MalignancyInherited Bone Marrow Failure SyndromeClonal Expansion+10 more
Mayo Clinic 2,000
Not applicableStudy completedNCT02380222
What this trial is testing

Patient-Reported Outcome Questionnaire for Systemic Mastocytosis

Who this might be right for
Aggressive Systemic Mastocytosis (ASM)SM w Assoc Clonal Hema Non-mast Cell Lineage Disease (SM-AHNMD)Mast Cell Leukemia (MCL)+2 more
Adelphi Values LLC 5
Not applicableLooking for participantsNCT06764459
What this trial is testing

Molecular Characterization of Patients With Acute Myeloid Leukemia and the Impact of Clonal Evolution in the Response to Therapeutic Treatments

Who this might be right for
Myeloid Leukemia, Acute
IRCCS Azienda Ospedaliero-Universitaria di Bologna 20
Not applicableLooking for participantsNCT06785077
What this trial is testing

Genetic Landscape in Women with Metastatic Ovarian Cancer Before and During Treatment with PARP Inhibitors

Who this might be right for
Leukemia, Myeloid, AcuteMyeloid DysplasiaOvarian Epithelial Cancer
European Institute of Oncology 157
Testing effectiveness (Phase 2)Looking for participantsNCT06566742
What this trial is testing

Study Evaluating Olutasidenib in Patients With IDH1-mutated Clonal Cytopenia of Undetermined Significance and Lower-risk Myelodysplastic/Syndromes/Chronic Myelomonocytic Leukemia.

Who this might be right for
Myelodysplastic SyndromesChronic Myelomonocytic LeukemiaClonal Cytopenia of Undetermined Significance
M.D. Anderson Cancer Center 15
Not applicableStudy completedNCT06463639
What this trial is testing

FLT3 Clonal Evolution in Patients With Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia
National Taiwan University Hospital 1,213
Testing effectiveness (Phase 2)Study completedNCT00782067
What this trial is testing

Efficacy and Safety of Midostaurin in Patients With Aggressive Systemic Mastocytosis or Mast Cell Leukemia

Who this might be right for
Leukemia
Novartis Pharmaceuticals 116
Testing effectiveness (Phase 2)Study completedNCT01036009
What this trial is testing

Withdrawal of Immunosuppression and Donor Lymphocyte Infusions Following Allogeneic Transplant for Pediatric Hematologic Malignancies

Who this might be right for
Acute LeukemiaAcute Myeloid LeukemiaAcute Lymphoblastic Leukemia+7 more
University of California, San Francisco 43
Not applicableLooking for participantsNCT06295965
What this trial is testing

Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers, CHANCES Study

Who this might be right for
Recurrent Fallopian Tube CarcinomaRecurrent Ovarian CarcinomaRecurrent Primary Peritoneal Carcinoma+7 more
University of Washington 2,000
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