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Results for “Colorectal Cancer (MSI-H)”

116 trials

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Showing 20 of 116 results

Testing effectiveness (Phase 2)Looking for participantsNCT07213609
What this trial is testing

Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

Who this might be right for
Neoplasms, ColorectalNeoplasms
GlaxoSmithKline 47
Not applicableStudy completedNCT06717763
What this trial is testing

Surgery Following Immune Checkpoint Inhibitions for Controlled Disease in Recurrent or Metastatic dMMR/MSI-H Colorectal Cancer

Who this might be right for
Colorectal Cancer
Sun Yat-sen University 40
Not applicableStudy completedNCT05871567
What this trial is testing

Predictive Value of DNA Mismatch Repair System in Colorectal Cancers

Who this might be right for
MSI-H Colorectal Cancer
University of Campania Luigi Vanvitelli 403
Testing effectiveness (Phase 2)WithdrawnNCT06365970
What this trial is testing

Niraparib and Dostarlimab for Patients With MMR-D/MSI-H Colorectal Cancers

Who this might be right for
MMR-D/MSI-H Colorectal Cancers
Ibrahim Halil Sahin
Early research (Phase 1)Active Not RecruitingNCT05544929
What this trial is testing

Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers

Who this might be right for
Carcinoma, Non-Small-Cell LungCutaneous MelanomaCarcinoma, Renal Cell+9 more
Novartis Pharmaceuticals 126
Testing effectiveness (Phase 2)Active Not RecruitingNCT04715633
What this trial is testing

PD-1 Inhibitors Combined With VEGF Inhibitors for Locally Advanced dMMR/MSI-H Colorectal Cancer

Who this might be right for
Colorectal CancerMicrosatellite Instability High
Sun Yat-sen University 53
Early research (Phase 1)Study completedNCT04357587
What this trial is testing

Safety and Feasibility of PD-1 Blockade in the Treatment of dMMR or MSI-H Rectal Cancer

Who this might be right for
Rectal Neoplasms
Case Comprehensive Cancer Center 6
Testing effectiveness (Phase 2)UnknownNCT04866862
What this trial is testing

Fruquitinib Combined With Camrelizumab in Non MSI-H/dMMR Refractory Colorectal Cancer

Who this might be right for
Colorectal Neoplasm
The First Affiliated Hospital with Nanjing Medical University 32
Early research (Phase 1)Study completedNCT03775850
What this trial is testing

EDP1503 in Patients With Colorectal Cancer, Breast Cancer, and Checkpoint Inhibitor Relapsed Tumors

Who this might be right for
Colorectal Cancer MetastaticTriple Negative Breast CancerNon Small Cell Lung Cancer+4 more
Evelo Biosciences, Inc. 69
Early research (Phase 1)Study completedNCT03374254
What this trial is testing

Safety and Efficacy of Pembrolizumab (MK-3475) Plus Binimetinib Alone or Pembrolizumab Plus Chemotherapy With or Without Binimetinib in Metastatic Colorectal Cancer (mCRC) Participants (MK-3475-651/KEYNOTE-651)

Who this might be right for
Metastatic Colorectal Cancer
Merck Sharp & Dohme LLC 116
Not applicableStudy completedNCT07194954
What this trial is testing

Dietary Fiber and Probiotics in Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer (MSI-H)Malnutrition (Calorie)
The First Hospital of Hebei Medical University 80
Testing effectiveness (Phase 2)Ended earlyNCT04258111
What this trial is testing

IBI310 in Combination with Sintilimab in Patients with DNA Mismatch Repair Deficient (dMMR)/microsatellite Instability High (MSI-H) Locally-advanced or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Innovent Biologics (Suzhou) Co. Ltd. 4
Testing effectiveness (Phase 2)Looking for participantsNCT06205836
What this trial is testing

Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer

Who this might be right for
Colorectal Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 33
Testing effectiveness (Phase 2)Active Not RecruitingNCT06640049
What this trial is testing

Dostarlimab in Participants With Untreated Locally Advanced Rectal Cancer in China

Who this might be right for
Neoplasms, Rectal
GlaxoSmithKline 23
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06423937
What this trial is testing

Fruquintinib Plus Camrelizumab and HAIC in the Treatment of Non-MSI-H Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Fudan University 129
Testing effectiveness (Phase 2)Active Not RecruitingNCT04895722
What this trial is testing

Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008)

Who this might be right for
Colorectal Cancer
Merck Sharp & Dohme LLC 302
Not applicableNot Yet RecruitingNCT07352280
What this trial is testing

Neoadjuvant Therapy With Tislelizumab for dMMR/MSI-H Stage II-III Colorectal Cancer

Who this might be right for
Colo-rectal Cancer (dMMR/MSI-H CRC)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 30
Large-scale testing (Phase 3)Looking for participantsNCT06520683
What this trial is testing

Adjuvant PD-1 Blockade for High-risk Stage-II DMMR/MSI-H Colorectal Cancer

Who this might be right for
Colorectal CancerMicrosatellite Instability High
Sun Yat-sen University 180
Not applicableStudy completedNCT03277235
What this trial is testing

Effect of a Resilience Model-Based Program for Patients With Newly Diagnosed Colorectal Cancer

Who this might be right for
Colorectal Cancer (MSI-H)
National Taiwan University Hospital 128
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07009145
What this trial is testing

QL1706 Plus Bevacizumab for Unresectable or Metastatic MSI-H/dMMR CRC

Who this might be right for
Unresectable Colorectal CancerMetastatic Colorectal Cancer (CRC)MSI-H/dMMR Colorectal Cancer
Qianfoshan Hospital 22
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