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Results for “Complement Mediated Diseases”

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Showing 16 of 0 results

Early research (Phase 1)Study completedNCT02983006
What this trial is testing

Study of DS-8273a With Nivolumab in Unresectable Stage III or Stage IV Melanoma

Who this might be right for
Melanoma
NYU Langone Health 12
Not applicableEnded earlyNCT05072912
What this trial is testing

Screening Study to Identify Patients With Complement Factor I Deficiencies

Who this might be right for
Previous Diagnosis With a Complement-mediated Disease and/or With Clinical Manifestations Reasonably Associated With Complement Factor I Deficiency
Catalyst Biosciences 113
Early research (Phase 1)Study completedNCT05937581
What this trial is testing

First-In-Human Study To Evaluate The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of Escalating Single And Multiple Doses Of CSL040 In Healthy Subjects

Who this might be right for
Complement-mediated Disorders
CSL Behring 62
Early research (Phase 1)Enrolling By InvitationNCT06723106
What this trial is testing

Phase 1b Long-term Extension Trial of RAY121 in Immunological Diseases (RAINBOW-LTE Trial)

Who this might be right for
Antiphospholipid Syndrome (APS)Bullous Pemphigoid (BP)Behçet's Syndrome (BS)+3 more
Chugai Pharmaceutical 144
Early research (Phase 1)Looking for participantsNCT07462780
What this trial is testing

A Phase I Clinical Trial to Evaluate CMS-D017 Following Single and Multiple Doses in Healthy Participants

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria, PNHComplement-mediated Kidney Disease
Shenzhen Kangzhe Biotechnology Co., Ltd. 88
Early research (Phase 1)Study completedNCT06209177
What this trial is testing

Study of ARO-CFB in Adult Healthy Volunteers

Who this might be right for
IgA Nephropathy
Arrowhead Pharmaceuticals 49
Early research (Phase 1)Study completedNCT07040787
What this trial is testing

Investigation of Drug-drug Interaction of HRS-5965 With Clopidogrel and Clarithromycin in Healthy Subjects

Who this might be right for
Complement Mediated Glomerular DiseasesHemolytic Anemia
Chengdu Suncadia Medicine Co., Ltd. 36
Testing effectiveness (Phase 2)Study completedNCT03124368
What this trial is testing

A Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGN

Who this might be right for
C3 GlomerulonephritisDense Deposit DiseaseC3 Glomerulopathy+2 more
Alexion Pharmaceuticals, Inc. 6
Early research (Phase 1)Study completedNCT06797375
What this trial is testing

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of RLYB116 in Healthy Participants

Who this might be right for
Hematologic DiseasesAutoimmune Diseases
Rallybio 16
Early research (Phase 1)Looking for participantsNCT05318534
What this trial is testing

Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Male and Female Subjects and Safety, Tolerability, Pharmacokinetics, and Pilot Efficacy Biomarkers in Subjects With Cold Agglutinin Disease

Who this might be right for
First in Man Study to Evaluate Initial Safety
Gliknik Inc. 70
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07363265
What this trial is testing

Efficacy and Safety of LP-005 Injection in Patients With Complement-Mediated Kidney Disease

Who this might be right for
Complement-mediated Renal Diseases
Longbio Pharma 46
Early research (Phase 1)Study completedNCT02502903
What this trial is testing

Safety, Tolerability and Activity of BIVV009 in Healthy Volunteers and Patients With Complement Mediated Disorders

Who this might be right for
Bullous Pemphigoid (BP)Cold Agglutinin Disease (CAD)Warm Autoimmune Hemolytic Anemia (WAIHA)+1 more
Bioverativ, a Sanofi company 122
Early research (Phase 1)Looking for participantsNCT06371417
What this trial is testing

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

Who this might be right for
Antiphospholipid Syndrome (APS)Bullous Pemphigoid (BP)Behçet's Syndrome (BS)+3 more
Chugai Pharmaceutical 144
Not applicableActive Not RecruitingNCT05985122
What this trial is testing

New Analytic Tools for aHUS and C3G Diagnosis

Who this might be right for
Hemolytic-Uremic SyndromeMembranoproliferative GlomerulonephritisHealthy
Mario Negri Institute for Pharmacological Research 180
Testing effectiveness (Phase 2)Active Not RecruitingNCT05121376
What this trial is testing

A Gene Therapy Study of BMN 331 in Subjects With Hereditary Angioedema

Who this might be right for
Hereditary AngioedemaHAE
BioMarin Pharmaceutical 44
Not applicableStudy completedNCT01945307
What this trial is testing

Complement 2: Blood Donations to Develop Vaccines Against Infectious Diseases

Who this might be right for
Complement Mediated Bacterial Killing in Healthy Adults
University of Oxford 101