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Results for “Complement System”

298 trials

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Showing 20 of 298 results

Not applicableStudy completedNCT03845400
What this trial is testing

Lanadelumab in Persons With Hereditary Angioedema (HAE) Type I or II in North America

Who this might be right for
Hereditary Angioedema (HAE)
Shire 168
Not applicableStudy completedNCT03558009
What this trial is testing

Epidemiological Analysis for Hereditary Angioedema Disease

Who this might be right for
Abdominal PainFunctional Abdominal Pain
CENTOGENE GmbH Rostock 2,318
Testing effectiveness (Phase 2)Looking for participantsNCT04183101
What this trial is testing

Evaluation of a Renin Inhibitor, Aliskiren, Compared to Enalapril, in C3 Glomerulopathy

Who this might be right for
C3 GlomerulopathyMembranoproliferative GlomerulonephritisComplement Abnormality+2 more
Region Skane 30
Large-scale testing (Phase 3)Study completedNCT05511922
What this trial is testing

PK Subtrial in Adolescent Patients With HAE Type I or II Participating in the KVD900-302 Trial

Who this might be right for
Hereditary Angioedema
KalVista Pharmaceuticals, Ltd. 11
Not applicableStudy completedNCT05109065
What this trial is testing

Peripheral Immune System in Individuals With Schizophrenia

Who this might be right for
SchizophreniaSchizo Affective DisorderSchizophreniform Disorders
Stanford University 63
Not applicableLooking for participantsNCT06909253
What this trial is testing

Ravulizumab Treatment Outcomes in Patients With Generalized Myasthenia Gravis

Who this might be right for
Myasthenia Gravis, Generalized
AstraZeneca 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT05120830
What this trial is testing

NTLA-2002 in Adults With Hereditary Angioedema (HAE)

Who this might be right for
Hereditary Angioedema
Intellia Therapeutics 37
Large-scale testing (Phase 3)Ended earlyNCT01275976
What this trial is testing

Effect of C1-esterase Inhibitor on Systemic Inflammation in Trauma Patients With a Femur or Pelvic Fracture

Who this might be right for
TraumaInflammationSepsis+1 more
UMC Utrecht 11
Large-scale testing (Phase 3)Study completedNCT03920293
What this trial is testing

Safety and Efficacy Study of Ravulizumab in Adults With Generalized Myasthenia Gravis

Who this might be right for
Generalized Myasthenia Gravis
Alexion Pharmaceuticals, Inc. 175
Testing effectiveness (Phase 2)Study completedNCT00000421
What this trial is testing

Serologically Active, Clinically Stable Systemic Lupus Erythematosus

Who this might be right for
Systemic Lupus Erythematosus
NYU Langone Health 154
Testing effectiveness (Phase 2)Study completedNCT02093533
What this trial is testing

Eculizumab in Primary MPGN

Who this might be right for
Membranoproliferative Glomerulonephritis
Mario Negri Institute for Pharmacological Research 10
Not applicableStudy completedNCT01059526
What this trial is testing

Observational Safety Study for KALBITOR (Ecallantide) in the Treatment of Acute Attacks of Hereditary Angioedema

Who this might be right for
Hereditary Angioedema (HAE)
Shire 81
Very early researchEnded earlyNCT01694381
What this trial is testing

Research Into the Effect of a Clot-dissolving Agent and Its Inhibitor

Who this might be right for
Acute Ischemic Stroke
TSI, LLC 8
Large-scale testing (Phase 3)Study completedNCT05067127
What this trial is testing

Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

Who this might be right for
C3GIC-MPGNC3 Glomerulopathy+9 more
Apellis Pharmaceuticals, Inc. 124
Testing effectiveness (Phase 2)Ended earlyNCT03459443
What this trial is testing

A Proof of Concept Study for a 12 Month Treatment in Patients With C3G or IC-MPGN Treated With ACH-0144471

Who this might be right for
C3 GlomerulonephritisC3 GlomerulopathyImmune Complex Membranoproliferative Glomerulonephritis+2 more
Alexion Pharmaceuticals, Inc. 22
Testing effectiveness (Phase 2)Study completedNCT01756157
What this trial is testing

Subcutaneous CINRYZE With Recombinant Human Hyaluronidase for Prevention of Angioedema Attacks

Who this might be right for
Hereditary Angioedema (HAE)
Shire 47
Not applicableStudy completedNCT04130191
What this trial is testing

Lanadelumab in Persons With Hereditary Angioedema (HAE) Type I or II

Who this might be right for
Hereditary Angioedema (HAE)
Shire 140
Early research (Phase 1)Study completedNCT02093923
What this trial is testing

A Double-Blind, Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of DX-2930 in Hereditary Angioedema Participants

Who this might be right for
Hereditary Angioedema (HAE)
Shire 38
Not applicableStudy completedNCT00004305
What this trial is testing

Study of Genetic Anomalies of Complement Related Proteins in Patients With IgA Glomerulonephritis

Who this might be right for
IGA Glomerulonephritis
National Center for Research Resources (NCRR) 105
Large-scale testing (Phase 3)Active Not RecruitingNCT06290128
What this trial is testing

Test the Effects and Safety of Riliprubart in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) for Which the Usual Treatments do Not Work

Who this might be right for
Chronic Inflammatory Demyelinating PolyradiculoneuropathyPolyneuropathy, Inflammatory Demyelinating, Chronic
Sanofi 109
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