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Results for “Complement System”

286 trials

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Showing 20 of 286 results

Not applicableLooking for participantsNCT06573723
What this trial is testing

Institutional Registry of Rare Diseases

Who this might be right for
Rare DiseasesAmyloidosisSarcoidosis+23 more
Hospital Italiano de Buenos Aires 380
Testing effectiveness (Phase 2)Looking for participantsNCT06919003
What this trial is testing

Improving Deceased-Donor Kidney Transplant Outcomes Via a Single Intragraft Injection of C1 Esterase Inhibitor (IMPROVE TRIAL)

Who this might be right for
Kidney Transplant
National Institute of Allergy and Infectious Diseases (NIAID) 180
Early research (Phase 1)Looking for participantsNCT06371417
What this trial is testing

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

Who this might be right for
Antiphospholipid Syndrome (APS)Bullous Pemphigoid (BP)Behçet's Syndrome (BS)+3 more
Chugai Pharmaceutical 144
Not applicableStudy completedNCT05033236
What this trial is testing

Platelets and Complement Activation in Coronary Artery Bypass Graft Surgery (CABG)

Who this might be right for
Cardiopulmonary BypassInflammatory ResponsePlatelet Dysfunction
Medical University Innsbruck 190
Large-scale testing (Phase 3)Study completedNCT01386658
What this trial is testing

A Pharmacokinetic, Tolerability and Safety Study of Icatibant in Children and Adolescents With Hereditary Angioedema

Who this might be right for
Hereditary Angioedema (HAE)
Shire 32
Large-scale testing (Phase 3)Study completedNCT04180163
What this trial is testing

Efficacy and Safety of Lanadelumab (SHP643) in Japanese Participants With Hereditary Angioedema (HAE)

Who this might be right for
Hereditary Angioedema (HAE)
Shire 12
Not applicableStudy completedNCT02821104
What this trial is testing

Complement and Cardiovascular Risk in Adolescents

Who this might be right for
Cardiovascular DiseaseType 2 Diabetes
Ohio State University 77
Not applicableLooking for participantsNCT05966467
What this trial is testing

Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies

Who this might be right for
Neuromyelitis Optica Spectrum DisorderNMOSDAQP4+ NMOSD
Alexion Pharmaceuticals, Inc. 122
Testing effectiveness (Phase 2)Study completedNCT03373461
What this trial is testing

Study of Safety and Efficacy of LNP023 in Patients With Kidney Disease Caused by Inflammation

Who this might be right for
IgA Nephropathy
Novartis Pharmaceuticals 112
Not applicableStudy completedNCT05397431
What this trial is testing

A Survey of Lanadelumab in Participants With Hereditary Angioedema

Who this might be right for
Hereditary Angioedema (HAE)
Takeda 155
Testing effectiveness (Phase 2)Study completedNCT04030598
What this trial is testing

Assess the Clinical Efficacy of Donidalorsen (Also Known as IONIS-PKK-LRx and ISIS 721744) in Participants With Hereditary Angioedema

Who this might be right for
Hereditary Angioedema
Ionis Pharmaceuticals, Inc. 23
Large-scale testing (Phase 3)Study completedNCT00168103
What this trial is testing

Human C1 Esterase Inhibitor (C1-INH) in Subjects With Acute Abdominal or Facial Hereditary Angioedema (HAE) Attacks

Who this might be right for
Hereditary Angioedema
CSL Behring 126
Large-scale testing (Phase 3)Study completedNCT00500656
What this trial is testing

Subcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema (HAE)

Who this might be right for
Hereditary Angioedema
Shire 85
Testing effectiveness (Phase 2)Study completedNCT04618211
What this trial is testing

Dose-ranging Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema

Who this might be right for
Hereditary AngioedemaHereditary Angioedema Type IHereditary Angioedema Type II+7 more
Pharvaris Netherlands B.V. 74
Large-scale testing (Phase 3)Study completedNCT00462709
What this trial is testing

Open-Label C1 Esterase Inhibitor (C1INH-nf) for the Prevention of Acute Hereditary Angioedema (HAE) Attacks

Who this might be right for
Hereditary Angioedema
Shire 146
Testing effectiveness (Phase 2)Study completedNCT01303952
What this trial is testing

Therapy of Chronic Cold Agglutinin Disease With Eculizumab

Who this might be right for
Cold Agglutinin Disease
University Hospital, Essen 13
Large-scale testing (Phase 3)WithdrawnNCT04898309
What this trial is testing

Efficacy and Safety of GNR-038 vs Berinert® in Patients With Hereditary Angioedema

Who this might be right for
Hereditary Angioedema
AO GENERIUM
Early research (Phase 1)Study completedNCT04349800
What this trial is testing

A Single Dose Safety, Tolerability, Pharmacokinetic and Food Effect Study of KVD900 (Sebetralstat) in Healthy Volunteers

Who this might be right for
Hereditary Angioedema
KalVista Pharmaceuticals, Ltd. 84
Not applicableUnknownNCT02159430
What this trial is testing

Hereditary AngioEdema, Neurobiology and Psychopathology

Who this might be right for
Hereditary AngioEdemaAnxietyDepression
University Hospital, Catania 35
Large-scale testing (Phase 3)Looking for participantsNCT06679881
What this trial is testing

Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE

Who this might be right for
Hereditary Angioedema (HAE)
Pharvaris Netherlands B.V. 130
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