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Results for “Complement System”

295 trials

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Showing 20 of 295 results

Testing effectiveness (Phase 2)Study completedNCT00904826
What this trial is testing

An Open Label Study of the Effects of Eculizumab in Neuromyelitis Optica

Who this might be right for
Neuromyelitis OpticaDevic's Disease
Mayo Clinic 14
Not applicableStudy completedNCT00004694
What this trial is testing

Study of Heparin Prophylaxis of Hereditary Angioedema Exacerbations

Who this might be right for
Angioedema
University of Iowa 24
Testing effectiveness (Phase 2)Ended earlyNCT05162066
What this trial is testing

Study to Evaluate the Safety, Tolerability of BCX9930 in Participants With Either Complement 3 Glomerulopathy (C3G), Immunoglobulin A Nephropathy (IgAN), or Primary Membranous Nephropathy (PMN)

Who this might be right for
Complement 3 GlomerulopathyImmunoglobulin A NephropathyMembranous Nephropathy
BioCryst Pharmaceuticals 2
Large-scale testing (Phase 3)Study completedNCT00097695
What this trial is testing

Subcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema

Who this might be right for
Angioedema
Shire 84
Not applicableStudy completedNCT06495151
What this trial is testing

Endometriosis and Complement System

Who this might be right for
EndometriosisComplement SystemAlternative Complement Pathway
Ankara City Hospital Bilkent 58
Large-scale testing (Phase 3)Active Not RecruitingNCT05556096
What this trial is testing

Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis

Who this might be right for
Generalized Myasthenia Gravis
Alexion Pharmaceuticals, Inc. 261
Not applicableStudy completedNCT01520623
What this trial is testing

Complement and Graft-versus-host Disease

Who this might be right for
Allografted With Myeloablative Conditioning
Assistance Publique - Hôpitaux de Paris 70
Large-scale testing (Phase 3)Study completedNCT06467084
What this trial is testing

Open-Label Safety, PK, and Efficacy Trial of Sebetralstat (KVD900) in Pediatric Patients (Ages 2-11) With HAE Type I or II

Who this might be right for
Hereditary Angioedema
KalVista Pharmaceuticals, Ltd. 36
Large-scale testing (Phase 3)Study completedNCT01188564
What this trial is testing

Efficacy, Safety and Immunogenicity Study of Recombinant Human C1 Inhibitor for the Treatment of Acute HAE Attacks

Who this might be right for
Hereditary Angioedema
Pharming Technologies B.V. 75
Testing effectiveness (Phase 2)Study completedNCT00000421
What this trial is testing

Serologically Active, Clinically Stable Systemic Lupus Erythematosus

Who this might be right for
Systemic Lupus Erythematosus
NYU Langone Health 154
Testing effectiveness (Phase 2)Active Not RecruitingNCT05120830
What this trial is testing

NTLA-2002 in Adults With Hereditary Angioedema (HAE)

Who this might be right for
Hereditary Angioedema
Intellia Therapeutics 37
Not applicableNot Yet RecruitingNCT06811467
What this trial is testing

Suicide Ideation in Hereditary Angioedema

Who this might be right for
Hereditary Angioedema (HAE)Suicidal IdeationCardiovascular Risk
Ivan Cherrez Ojeda 100
Large-scale testing (Phase 3)Looking for participantsNCT06607627
What this trial is testing

PK, PD, Safety, and Efficacy Study of Gefurulimab in Pediatric Patients With AChR+ Generalized Myasthenia Gravis

Who this might be right for
Generalized Myasthenia GravisgMG
Alexion Pharmaceuticals, Inc. 12
Large-scale testing (Phase 3)Study completedNCT05819775
What this trial is testing

CSL312_3003 Safety and Pharmacokinetic Study in Subjects 2 to 11 Years of Age With Hereditary Angioedema

Who this might be right for
Hereditary Angioedema (HAE)
CSL Behring 22
Not applicableStudy completedNCT04635098
What this trial is testing

DexmedetOmidine Complement Treats Chronic insOmnia and Improves Circadian Rhythm (DOCTOR)

Who this might be right for
Chronic Insomnia
Ruijin Hospital 64
Not applicableNot Yet RecruitingNCT07598448
What this trial is testing

Complement 3 Glomerulopathy (C3G) Patients Treated With Iptacopan Through an Early Access Program in Spain

Who this might be right for
Complement 3 Glomerulopathy
Novartis Pharmaceuticals 35
Early research (Phase 1)Looking for participantsNCT06371417
What this trial is testing

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

Who this might be right for
Antiphospholipid Syndrome (APS)Bullous Pemphigoid (BP)Behçet's Syndrome (BS)+3 more
Chugai Pharmaceutical 144
Large-scale testing (Phase 3)Study completedNCT00457015
What this trial is testing

Efficacy Study of DX-88 (Ecallantide) to Treat Acute Attacks of Hereditary Angioedema (HAE)

Who this might be right for
Hereditary Angioedema (HAE)
Shire 96
Not applicableStudy completedNCT03450642
What this trial is testing

Complement Diagnosis of Acute Appendicitis

Who this might be right for
Acute Appendicitis
University of Exeter 70
Testing effectiveness (Phase 2)Study completedNCT01359969
What this trial is testing

Safety of Ruconest in 2-13 Year Old Hereditary Angioedema (HAE) Patients

Who this might be right for
Hereditary Angioedema
Pharming Technologies B.V. 57
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