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Results for “Congenital, Familial and Genetic Disorders”

943 trials

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Showing 20 of 943 results

Not applicableStudy completedNCT05171426
What this trial is testing

Incidental Cancer in Familial Adenomatous Polyposis

Who this might be right for
Cancer
Dr. Ersin Arslan Education and Training Hospital 55
Not applicableLooking for participantsNCT06933212
What this trial is testing

Effect of the Mediterranean Diet in Patients Affected by CADASIL and Cerebral Amyloid Angiopathy.

Who this might be right for
Cerebral Amyloid AngiopathyCAA - Cerebral Amyloid Angiopathy
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta 86
Not applicableLooking for participantsNCT04638621
What this trial is testing

Dilated Cardiomyopathy-Cardiac Magnetic Resonance (DCM-CMR) Ancillary Study

Who this might be right for
Dilated Cardiomyopathy
Ohio State University 650
Testing effectiveness (Phase 2)Study completedNCT00641147
What this trial is testing

Curcumin in Treating Patients With Familial Adenomatous Polyposis

Who this might be right for
Familial Adenomatous Polyposis
National Cancer Institute (NCI) 44
Testing effectiveness (Phase 2)Looking for participantsNCT04941599
What this trial is testing

2-Hydroxybenzylamine (2-HOBA) to Reduce HDL Modification and Improve HDL Function in Familial Hypercholesterolemia (FH)

Who this might be right for
Familial Hypercholesterolemia
Vanderbilt University Medical Center 72
Testing effectiveness (Phase 2)Study completedNCT04188964
What this trial is testing

Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Burosumab in Patients Less Than 1 Year of Age

Who this might be right for
X-linked Hypophosphatemia (XLH)
Kyowa Kirin Pharmaceutical Development Ltd 16
Very early researchStudy completedNCT03119558
What this trial is testing

PET/MRI Evaluation of Cardiac Amyloid

Who this might be right for
Cardiac Amyloidosis
Stanford University 9
Not applicableLooking for participantsNCT03193476
What this trial is testing

Registry for Patients With X-Linked Hypophosphatemia

Who this might be right for
X-Linked Hypophosphatemia
Kyowa Kirin Pharmaceutical Development Ltd 1,343
Early research (Phase 1)Study completedNCT00036959
What this trial is testing

ABT-751 in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+6 more
National Institutes of Health Clinical Center (CC) 90
Testing effectiveness (Phase 2)WithdrawnNCT05448391
What this trial is testing

Evaluate RIST4721 in Familial Mediterranean Fever (FMF)

Who this might be right for
Familial Mediterranean Fever
Aristea Therapeutics, Inc.
Not applicableLooking for participantsNCT06813443
What this trial is testing

Characterization of Patients With Cardiomyopathy to Identify Critical Patients Candidates for Cardiac Transplantation

Who this might be right for
CardiomyopathiesAmyloidosis CardiacFabry Disease+14 more
IRCCS Azienda Ospedaliero-Universitaria di Bologna 700
Testing effectiveness (Phase 2)Study completedNCT02048410
What this trial is testing

Efficacy of a New Symbiotic Formulation in Children With Familial Hypercholesterolemia

Who this might be right for
DyslipidemiaFamilial Hypercholesterolemia
Federico II University 40
Large-scale testing (Phase 3)Ended earlyNCT00585312
What this trial is testing

Trial In Pediatric Patients With Familial Adenomatous Polyposis (FAP)

Who this might be right for
Adenomatous Polyposis Coli
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 106
Not applicableNot Yet RecruitingNCT07296861
What this trial is testing

HomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Syndrome

Who this might be right for
Down SyndromeChild Obesity
UNC Lineberger Comprehensive Cancer Center 38
Not applicableStudy completedNCT00007046
What this trial is testing

Genetic Study of Patients and Families With Diaphyseal Medullary Stenosis With Malignant Fibrous Histiocytoma of the Bone

Who this might be right for
StenosisHistiocytoma
National Center for Research Resources (NCRR)
Not applicableLooking for participantsNCT06535542
What this trial is testing

Integrating Whole Genome Sequencing and Digital Twins Into the Management of Hypercholesterolemia in Emiratis

Who this might be right for
Hypercholesterolemia, Autosomal DominantHypercholesterolemia, Autosomal RecessiveFamilial Combined Hypercholesterolemia
Abu Dhabi Health Services Company 40
Not applicableLooking for participantsNCT04587648
What this trial is testing

Cardiac Amyloidosis in HFpEF

Who this might be right for
Heart Failure With Preserved Ejection FractionAmyloidosis Cardiac
National Taiwan University Hospital 250
Testing effectiveness (Phase 2)Ended earlyNCT02862600
What this trial is testing

Open-Label Study of Perhexiline in Patients With Hypertrophic Cardiomyopathy and Moderate to Severe Heart Failure

Who this might be right for
Cardiomyopathy, HypertrophicCardiomyopathy, Hypertrophic, Familial
Heart Metabolics Limited 35
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06148311
What this trial is testing

Dexmedetomidine Sublingual Film for the Ambulatory Treatment of Hyperadrenergic Autonomic Crisis in Patients With Familial Dysautonomia

Who this might be right for
Familial Dysautonomia
NYU Langone Health 15
Not applicableActive Not RecruitingNCT02194387
What this trial is testing

Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members

Who this might be right for
Body Mass Index 25 or GreaterBRCA1 Gene MutationBRCA2 Gene Mutation+8 more
M.D. Anderson Cancer Center 337
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