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Results for “Congenital Anemias”

1,824 trials

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Showing 20 of 1,824 results

Early research (Phase 1)Ended earlyNCT05660265
What this trial is testing

Investigate the Safety, Tolerability, and Pharmacokinetics of Oral GSK4172239D Compared With Placebo in Sickle Cell Disease Participants Aged 18 to 50 Years

Who this might be right for
Hematologic DiseasesAnaemia, Sickle Cell
GlaxoSmithKline 11
Testing effectiveness (Phase 2)Study completedNCT02797964
What this trial is testing

A Phase 1/2 Trial of SRA737 in Subjects With Advanced Cancer

Who this might be right for
Advanced Solid Tumors or Non-Hodgkin's Lymphoma (NHL)
Sierra Oncology LLC - a GSK company 107
Testing effectiveness (Phase 2)Study completedNCT02125877
What this trial is testing

Phase II Study to Investigate the Benefits of an Improved Deferasirox Formulation (Film-coated Tablet)

Who this might be right for
Chronic Iron Overload Due to Transfusion-dependant Anemias
Novartis Pharmaceuticals 173
Early research (Phase 1)WithdrawnNCT02659644
What this trial is testing

Oral L-citrulline in Sickle Cell Disease

Who this might be right for
Sickle Cell Disease
University of Mississippi Medical Center
Not applicableStudy completedNCT01123863
What this trial is testing

The Brigance Assessment Of Individual Neurodevelopment In Young Children With Sickle Cell Disease- 2

Who this might be right for
Sickle Cell Disease
St. Jude Children's Research Hospital 248
Testing effectiveness (Phase 2)Looking for participantsNCT04774536
What this trial is testing

Transplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease

Who this might be right for
Sickle Cell Disease
Mark Walters, MD 9
Not applicableStudy completedNCT00789516
What this trial is testing

The Change of Coagulation Markers in Children With β-thalassemia Disease After Stem Cell Transplantation

Who this might be right for
Thalassemia
Mahidol University 60
Not applicableLooking for participantsNCT05012111
What this trial is testing

Natural History of Acquired and Inherited Bone Marrow Failure Syndromes

Who this might be right for
Severe Aplastic AnemiaTelomere Biology DisordersInherited Bone Marrow Failure Syndromes
National Heart, Lung, and Blood Institute (NHLBI) 1,000
Early research (Phase 1)Study completedNCT01506544
What this trial is testing

Pharmacokinetics (PK) of Liquid Hydroxyurea in Pediatric Patients With Sickle Cell Anemia

Who this might be right for
Sickle Cell Anemia
Children's Mercy Hospital Kansas City 39
Post-approval studies (Phase 4)Study completedNCT00649298
What this trial is testing

A Clinical Trial of IntensiVE Dialysis

Who this might be right for
Renal Replacement TherapyRenal DialysisEnd Stage Kidney Disease+2 more
The George Institute 200
Large-scale testing (Phase 3)Study completedNCT01125254
What this trial is testing

Amlodipine Use in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major

Who this might be right for
Thalassemia Major
University of Campinas, Brazil 10
Testing effectiveness (Phase 2)Study completedNCT00425477
What this trial is testing

Bexarotene and GM-CSF in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia

Who this might be right for
LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Diseases
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 26
Not applicableUnknownNCT02067130
What this trial is testing

Utility of Fibroscan in Estimating Hepatic Iron Concentration

Who this might be right for
Hereditary Anemias
University of British Columbia 30
Post-approval studies (Phase 4)UnknownNCT01323608
What this trial is testing

The Effect of Vitamin D Supplementation on Calcium Excretion in Thalassemia: a Dose Response Study

Who this might be right for
Thalassemia Major
Weill Medical College of Cornell University 40
Early research (Phase 1)Study completedNCT02998450
What this trial is testing

IMR-687 in Healthy Adult Volunteers

Who this might be right for
Sickle Cell DiseaseSickle-Cell; Hb-SCSickle Beta 0 Thalassemia
Cardurion Pharmaceuticals, Inc. 66
Early research (Phase 1)Study completedNCT00077558
What this trial is testing

3-AP Followed By Fludarabine In Treating Patients With Relapsed or Refractory Acute or Chronic Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Diseases
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Testing effectiveness (Phase 2)Looking for participantsNCT06260891
What this trial is testing

Zinc Supplementation in Sickle Cell Disease: A Precursor to the Think Zinc for Bones Trial

Who this might be right for
Sickle Cell Disease
University of California, San Francisco 34
Early research (Phase 1)Ended earlyNCT04925206
What this trial is testing

A Safety and Efficacy Study Evaluating ET-01 in Subjects with Transfusion Dependent Β-Thalassaemia

Who this might be right for
Transfusion Dependent Beta-Thalassaemia
EdiGene (GuangZhou) Inc. 8
Not applicableNot Yet RecruitingNCT06084247
What this trial is testing

The Efficacy of the KARL STORZ Curved Fetoscope and Straight Fetoscope for Laser Photocoagulation of Placental Anastomoses

Who this might be right for
Twin to Twin Transfusion Syndrome
Jimmy Espinoza 160
Testing effectiveness (Phase 2)Study completedNCT01005576
What this trial is testing

Reduced Intensity Transplant Conditioning Regimen for Severe Thalassemia

Who this might be right for
Severe Thalassemia
Washington University School of Medicine 21
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