Testing effectiveness (Phase 2)Study completedNCT00657605What this trial is testingEffects of Human Leptin ReplacementWho this might be right forObesityMetabolic SyndromeDiabetes University of Miami 3
Large-scale testing (Phase 3)Active Not RecruitingNCT06548100What this trial is testingThe Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD)Who this might be right forGeneralized Lipodystrophy Regeneron Pharmaceuticals 9
Not applicableAvailableNCT04710056What this trial is testingExpanded Access to REGN4461 for Patients With Diseases Associated With Deficient Leptin SignalingWho this might be right forLipodystrophyGeneralized Lipodystrophy (GLD)Monogenic Obesity (MOB) Regeneron Pharmaceuticals
Not applicableStudy completedNCT04063488What this trial is testingThe Effects of Metreleptin in Congenital Leptin DeficiencyWho this might be right forCongenital Leptin Deficiency (Disorder) Northwestern University 2
Testing effectiveness (Phase 2)Study completedNCT00659828What this trial is testingEffects of Leptin Replacement in ChildrenWho this might be right forObesityMetabolic SyndromeDiabetes University of Miami 1
Not applicableStudy completedNCT02495961What this trial is testingStudy of Chronic Degenerative DiseasesWho this might be right forMetabolic Syndrome X Asociación Científica Latina A.C. 57