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Results for “Corneal Blindness”

18 trials

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Showing 18 of 18 results

Very early researchLooking for participantsNCT06451172
What this trial is testing

Novel Antisense Oligonucleotide Eye Drops for Treating Antibiotic-Resistant Bacterial Keratitis

Who this might be right for
Bacterial KeratitisAntibiotic-resistant BacteriaInfections, Bacterial+7 more
Eye & ENT Hospital of Fudan University 20
Not applicableNot Yet RecruitingNCT07526389
What this trial is testing

Evaluation of the Efficacy and Safety of Aspheric Keratoprosthesis in the Treatment of Patients With Corneal Blindness: A Clinical Study

Who this might be right for
KeratoprosthesisCorneal Blindness
Shanghai Vision Science Engineer Medical Equipment Co., Ltd 54
Not applicableLooking for participantsNCT06174376
What this trial is testing

Clinical Outcomes of the Gore Synthetic Cornea Device

Who this might be right for
Corneal Opacity
W.L.Gore & Associates 10
Not applicableStudy completedNCT03753893
What this trial is testing

Ocular Manifestations in Rheumatic Diseases

Who this might be right for
UveitisConjunctivitisKeratoconjunctivitis Sicca+15 more
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 5,000
Large-scale testing (Phase 3)Ended earlyNCT00516399
What this trial is testing

A Clinical Trial of the Treatment of Fungal Corneal Ulcers With Povidone-Iodine

Who this might be right for
Fungal Keratitis
University of California, Los Angeles 78
Not applicableStudy completedNCT01950598
What this trial is testing

Frozen Versus Fresh Corneal Carriers for the Boston KPro Type I Donor Carriers

Who this might be right for
Corneal BlindnessBoston Keratoprosthesis Type I Candidate
Marie-Claude Robert 37
Not applicableWithdrawnNCT03421548
What this trial is testing

Implantable Intraocular Pressure Sensor for Glaucoma Monitoring in Patients With Boston Keratoprosthesis Type 1

Who this might be right for
GlaucomaBlindness, AcquiredKeratitis, Herpetic+4 more
Centre hospitalier de l'Université de Montréal (CHUM)
Not applicableStudy completedNCT04560790
What this trial is testing

Safety and Efficacy of CRISPR/Cas9 mRNA Instantaneous Gene Editing Therapy to Treat Refractory Viral Keratitis

Who this might be right for
Viral KeratitisBlindness EyeHerpes Simplex Virus Infection+1 more
Shanghai BDgene Co., Ltd. 3
Testing effectiveness (Phase 2)Study completedNCT01765244
What this trial is testing

Allogeneic Tissue Engineering (Nanostructured Artificial Human Cornea) in Patients With Corneal Trophic Ulcers in Advanced Stages, Refractory to Conventional (Ophthalmic) Treatment

Who this might be right for
Severe Trophic Corneal Ulcers Refractory to Conventional TreatmentSequelae of Previous Trophic Corneal Ulcers
Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud 16
Not applicableNot Yet RecruitingNCT03884569
What this trial is testing

Cultivated Limbal Epithelial Transplantation (CLET) for Limbal Stem Cell Deficiency (LSCD)

Who this might be right for
Limbal Stem-cell Deficiency
Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA 30
Not applicableEnded earlyNCT04485858
What this trial is testing

First in Human (FIH) Study to Assess Safety and Efficacy of the CorNeat KPro for the Treatment of Corneal Blindness

Who this might be right for
Corneal DiseaseCorneal OpacityCorneal Injuries
CorNeat Vision Ltd. 10
Not applicableTemporarily pausedNCT05694247
What this trial is testing

Study to Evaluate the Clinical Safety and Performance of the CorNeat KPro for Treatment of Corneal Blindness

Who this might be right for
Corneal DiseaseCorneal OpacityCorneal Injuries
CorNeat Vision Ltd. 40
Testing effectiveness (Phase 2)Study completedNCT00386958
What this trial is testing

A Clinical Trial of Povidone-Iodine for the Treatment of Bacterial Corneal Ulcers

Who this might be right for
Infected Corneal UlcersBacterial KeratitisCorneal Ulcer+1 more
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center 172
Not applicableStudy completedNCT04653922
What this trial is testing

Evaluation of Safety and Efficacy of a Bioengineered Corneal Implant for Treatment of Keratoconus

Who this might be right for
Keratoconus
LinkoCare Life Sciences AB 20
Early research (Phase 1)UnknownNCT02948023
What this trial is testing

Stem Cells Therapy for Corneal Blindness

Who this might be right for
Corneal InjuriesCorneal BurnsCorneal Scars and Opacities
L.V. Prasad Eye Institute 100
Not applicableEnded earlyNCT03126903
What this trial is testing

A Clinical Study to Evaluate the KeraKlear Keratoprosthesis in Patients With Corneal Opacity

Who this might be right for
Corneal Blindness
KeraMed, Inc. 11
Testing effectiveness (Phase 2)WithdrawnNCT01256489
What this trial is testing

Infliximab to Improve Retention of the Boston Keratoprosthesis in Patients After Stevens Johnson Syndrome/ Toxic Epidermal Necrolysis (SJS/TENS)

Who this might be right for
Stevens-Johnson SyndromeCorneal Blindness
Massachusetts Eye and Ear Infirmary
Not applicableLooking for participantsNCT01793168
What this trial is testing

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Who this might be right for
Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more
Sanford Health 20,000