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Results for “Cowden's Disease”

15 trials

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Showing 15 of 15 results

Not applicableLooking for participantsNCT03702309
What this trial is testing

Liquid Biopsy Evaluation and Repository Development at Princess Margaret

Who this might be right for
CancerBreast CancerLung Cancer+15 more
University Health Network, Toronto 2,500
Not applicableLooking for participantsNCT06712095
What this trial is testing

Video Capsule Examination in Patients With Lynch Syndrome

Who this might be right for
Lynch SyndromeLi Fraumeni SyndromePTEN Hamartoma Syndrome+7 more
Royal Marsden NHS Foundation Trust 25
Testing effectiveness (Phase 2)Study completedNCT00971789
What this trial is testing

Sirolimus to Treat Cowden Syndrome and Other PTEN Hamartomatous Tumor Syndromes

Who this might be right for
Cowden's DiseaseHamartoma Syndrome, Multiple
National Cancer Institute (NCI) 18
Not applicableStudy completedNCT00040222
What this trial is testing

Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer

Who this might be right for
Familial Ovarian CancerFamilial Breast CancerBRCA1-associate Malignancies+1 more
National Cancer Institute (NCI) 377
Not applicableLooking for participantsNCT06523582
What this trial is testing

Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients

Who this might be right for
Neuroendocrine NeoplasmNeuroendocrine Neoplasm of Gastrointestinal TractNeuroendocrine Neoplasm of Lung+23 more
Universidad Nacional Autonoma de Mexico 750
Not applicableTemporarily pausedNCT05630105
What this trial is testing

Cancer Risk Assessment in Patients With a Constitutional Alteration of the PTEN Gene

Who this might be right for
PTEN Gene Mutation
Institut Bergonié 430
Not applicableUnknownNCT06163365
What this trial is testing

Inherited Cancer Early Diagnosis (ICED) Study

Who this might be right for
Li Fraumeni SyndromeLynch SyndromeHereditary Diffuse Gastric Cancer+5 more
Royal Marsden NHS Foundation Trust 100
Not applicableLooking for participantsNCT06805734
What this trial is testing

Natural History With Focus on Oncological Risk Evaluation in Pediatric Patients With PTEN Pathogenic Variants

Who this might be right for
PTEN Hamartoma Syndrome
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta 50
Testing effectiveness (Phase 2)WithdrawnNCT06080165
What this trial is testing

Sirolimus for Improving Social Abilities in People With PTEN Germline Mutations

Who this might be right for
PTEN Gene MutationPTEN Hamartoma Tumor SyndromePTEN Hamartoma Syndrome
Stanford University
Not applicableLooking for participantsNCT06888388
What this trial is testing

Long-term Safety of Nipple Sparing Mastectomy in Women With High Penetrance Breast Cancer Susceptibility Genes in Breast Cancer

Who this might be right for
Breast Cancer Surgery
Sir Mortimer B. Davis - Jewish General Hospital 4,700
Not applicableUnknownNCT01987518
What this trial is testing

French Digestive Polyposis Cohorte Family Adenomatous Polyposis With APC and MYH Gene Mutations , Cowden's Disease With PTEN Gene Mutation, Peutz Jeghers Disease With STK 11 Gene Mutation ,juvénil Polyposis With SMAD 4 Gene Mutation , Serrated and Hyperplastic Polyposis

Who this might be right for
Quality of Life
Hôpital Edouard Herriot 350
Testing effectiveness (Phase 2)Study completedNCT00600275
What this trial is testing

A Phase I/II Study of BGT226 in Adult Patients With Advanced Solid Malignancies Including Patients With Advanced Breast Cancer

Who this might be right for
Solid TumorsBreast CancerCowden Syndrome
Novartis Pharmaceuticals 57
Large-scale testing (Phase 3)Not Yet RecruitingNCT07218575
What this trial is testing

Double-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline Mutations

Who this might be right for
Cowden's DiseaseCowden's SyndromeLhermitte-Duclos Disease+6 more
Boston Children's Hospital 60
Early research (Phase 1)Study completedNCT00620594
What this trial is testing

A Phase I/II Study of BEZ235 in Patients With Advanced Solid Malignancies Enriched by Patients With Advanced Breast Cancer

Who this might be right for
Breast CancerAdvanced Solid TumorsCowden Syndrome
Novartis Pharmaceuticals 183
Testing effectiveness (Phase 2)Study completedNCT04094675
What this trial is testing

Sirolimus for Cowden Syndrome With Colon Polyposis

Who this might be right for
PTEN Gene MutationPTEN Hamartoma Tumor SyndromePTEN Hamartoma Syndrome+4 more
Ohio State University 5