Early research (Phase 1)Looking for participantsNCT05453695What this trial is testingIntravenous DNase I for the Treatment of Sepsis (IDEALSepsisI)Who this might be right forSepsisCritical Illness McMaster University 36
Not applicableLooking for participantsNCT06750939What this trial is testingThe Impact of Propofol and Ketamine on Cardiovascular Collapse During Induction for IntubationWho this might be right forCardiovascular CollapseIntubation ComplicationAnaesthetic Complication Cardiac Kocaeli City Hospital 128
Not applicableNot Yet RecruitingNCT06156072What this trial is testingUltrasound-guided Blood Sampling Drawing for Microbiological Analysis in the Critically IllWho this might be right forSepsisSeptic ShockInfections+1 more Fondazione Policlinico Universitario Agostino Gemelli IRCCS 100
Not applicableUnknownNCT04926610What this trial is testingThe Effect of Proactive Clinical Ethics Consultations on End-of-life Care of the Critically Ill in the Intensive Care SettingsWho this might be right forProactive Clinical Ethics Consultationthe Critically Ill Kaohsiung Medical University Chung-Ho Memorial Hospital 224
Not applicableStudy completedNCT00890513What this trial is testingFamily Satisfaction in the Intensive Care Unit - a Multicentre AssessmentWho this might be right forCritical Illness Insel Gruppe AG, University Hospital Bern 1,200
Large-scale testing (Phase 3)UnknownNCT03871244What this trial is testingPilot Optimizing Transfusion Thresholds in Critically-ill Children With AnaemiaWho this might be right forAnemia St. Justine's Hospital 120
Not applicableLooking for participantsNCT07130799What this trial is testingInnate Immune Response Monitoring Via Monocyte HLA-DR in Severe Intra-abdominal Infections at Risk of Fungal InfectionWho this might be right forIntra-abdominal InfectionCritical IllnessPost-Op Infection+2 more Central Hospital, Nancy, France 100
Not applicableLooking for participantsNCT05246098What this trial is testingREVIVe: Frailty, Rehabilitation, and Outcomes in Critically Ill Adult and Pediatric Survivors of COVID-19 or ARIWho this might be right forRespiratory DiseaseCOVID-19Viral Infection McMaster University 900
Not applicableUnknownNCT06156098What this trial is testingBedside Renal Ultrasound Assessment in Patients With Acute Kidney InjuryWho this might be right forCritical Illness Qin Zhang 100
Not applicableUnknownNCT05580367What this trial is testingGut-Brain-Axis/Lung-Brain-Axis and Mental Ill Health in Critical IllnessWho this might be right forMental Health IssueCritical IllnessGut Microbiome University Hospital Southampton NHS Foundation Trust 60
Large-scale testing (Phase 3)Study completedNCT03133377What this trial is testingTreatment of Invasively Ventilated Adults With Early Activity and MobilisationWho this might be right forCritically Ill, Mechanically Ventilated Australian and New Zealand Intensive Care Research Centre 750
Not applicableStudy completedNCT00789412What this trial is testingSurgical Stress Index as a Tool for Monitoring Analgesia and/or Sedation in Critically Ill PatientsWho this might be right forAnalgesiaSedationMechanical Ventilation+4 more University Hospital Schleswig-Holstein 60
Large-scale testing (Phase 3)Ended earlyNCT03380507What this trial is testingEvaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic ShockWho this might be right forSeptic ShockCritical Illness Hamad Medical Corporation 106
Not applicableStudy completedNCT04356144What this trial is testingThrombomodulin-modified Thrombin Generation Assay (TGA-TM) in Patients With Critical InfectionsWho this might be right forDisseminated Intravascular CoagulationCritical IllnessSars-CoV2+3 more Medical University of Vienna 58
Not applicableStudy completedNCT03388463What this trial is testingSingle Dose Omeprazole Versus High Dose in High-risk Critically Ill Patients.Who this might be right forCritical Illness Menoufia University 110
Not applicableTemporarily pausedNCT05197231What this trial is testingInvestigating the Anabolic Response to Resistance Exercise During Critical IllnessWho this might be right forCritical IllnessMuscle Loss Karolinska University Hospital 24
Not applicableNot Yet RecruitingNCT07385963What this trial is testingCorrelation Between EIT-based Pulse Wave Method for Pulmonary Perfusion Monitoring and Pulmonary Artery Catheter-based Stroke Volume MeasurementWho this might be right forShockAcute Respiratory Distress Syndrome Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 19
Not applicableStudy completedNCT00996099What this trial is testingContinuous Glucose Monitoring Combined With Computer Algorithm for Intensive Insulin Therapy in Cardiosurgical PatientsWho this might be right forHyperglycemiaCardiac Surgery Charles University, Czech Republic 24
Not applicableActive Not RecruitingNCT02905812What this trial is testingPilot Clinical Trial of an Integrative Intervention to Improve Critically Ill Patients' Delirium and Related OutcomesWho this might be right forDelirium University of Alberta 27
Post-approval studies (Phase 4)Study completedNCT05742295What this trial is testingPrevention of Cefoperazone-induced CoagulopathyWho this might be right forAntibiotic Side Effect Helwan University 56