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Results for “Crizotinib”

124 trials

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Showing 20 of 124 results

Large-scale testing (Phase 3)Study completedNCT02604342
What this trial is testing

Alectinib Versus Pemetrexed or Docetaxel in Anaplastic Lymphoma Kinase (ALK)-Positive Advanced Non-Small Cell Lung Cancer (NSCLC) Participants Previously Treated With Platinum-Based Chemotherapy and Crizotinib

Who this might be right for
Non-small Cell Lung Cancer
Hoffmann-La Roche 119
Testing effectiveness (Phase 2)Ended earlyNCT04030429
What this trial is testing

Crizotinib in c-MET Mutation Metastatic/Recurrent/Persistent Endometrial Cancer

Who this might be right for
Endometrial Cancer Recurrent
National Cheng-Kung University Hospital 40
Testing effectiveness (Phase 2)Study completedNCT03088930
What this trial is testing

Evaluating Crizotinib in the Neoadjuvant Setting in Patients With Non-small Cell Lung Cancer

Who this might be right for
Lung Cancer, Nonsmall Cell
University of Colorado, Denver 3
Early research (Phase 1)Study completedNCT00939731
What this trial is testing

Relative Drug Exposures Of Two Formulations of PF-02341066

Who this might be right for
Healthy
Pfizer 24
Early research (Phase 1)Study completedNCT01149785
What this trial is testing

Estimation Of Effect Of Ketoconazole On Pharmacokinetics Of Crizotinib In Healthy Volunteers

Who this might be right for
Healthy
Pfizer 15
Early research (Phase 1)Study completedNCT01606878
What this trial is testing

Crizotinib and Combination Chemotherapy in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma

Who this might be right for
Childhood Solid NeoplasmRecurrent Childhood Anaplastic Large Cell LymphomaRecurrent Neuroblastoma
Children's Oncology Group 46
Early research (Phase 1)Ended earlyNCT02511184
What this trial is testing

Crizotinib Plus Pembrolizumab In Alk-Positive Advanced Non Small Cell Lung Cancer Patients

Who this might be right for
ALK-positive Advanced NSCLC
Pfizer 9
Not applicableNo Longer AvailableNCT03085186
What this trial is testing

Treatment With Crizotinib Single Patient Expanded Access IND 134375

Who this might be right for
Inflammatory Myofibroblastic Tumour
Jean M. Tersak, M.D.
Early research (Phase 1)Study completedNCT01644773
What this trial is testing

Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)

Who this might be right for
Diffuse Intrinsic Pontine GliomaHigh-grade Glioma
St. Jude Children's Research Hospital 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439266
What this trial is testing

Testing Crizotinib as a Potential Targeted Treatment in Cancers With ALK Genetic Changes (MATCH-Subprotocol F)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 5
Early research (Phase 1)Looking for participantsNCT04693468
What this trial is testing

Talazoparib and Palbociclib, Axitinib, or Crizotinib for the Treatment of Advanced or Metastatic Solid Tumors, TalaCom Trial

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmRecurrent Malignant Solid Neoplasm
M.D. Anderson Cancer Center 111
Not applicableUnknownNCT03647111
What this trial is testing

Real World Study of First Line Crizotinib for ALK Rearranged Non-squamous Non-small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Hunan Province Tumor Hospital 120
Testing effectiveness (Phase 2)Study completedNCT04283669
What this trial is testing

Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

Who this might be right for
Neurofibromatosis 2Progressive Vestibular Schwannoma (VS)
University of Alabama at Birmingham 12
Testing effectiveness (Phase 2)UnknownNCT04056572
What this trial is testing

Study of TQ-B3139 in Subjects With Anaplastic Lymphoma Kinase (ALK) Positive Non-Small Cell Lung Cancer (NSCLC) Previously Treated With Crizotinib

Who this might be right for
ALK-positive NSCLC
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 135
Large-scale testing (Phase 3)Study completedNCT03194893
What this trial is testing

A Rollover Study of Alectinib in Patients With Anaplastic Lymphoma Kinase (ALK)-Positive or Rearranged During Transfection (RET)-Positive Cancer

Who this might be right for
Neoplasms
Hoffmann-La Roche 50
Testing effectiveness (Phase 2)Study completedNCT02094573
What this trial is testing

Evaluate the Efficacy of Brigatinib (AP26113) in Participants With Anaplastic Lymphoma Kinase (ALK)-Positive, Non-small Cell Lung Cancer (NSCLC) Previously Treated With Crizotinib

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Ariad Pharmaceuticals 222
Large-scale testing (Phase 3)Looking for participantsNCT07804186
What this trial is testing

Study of Adjuvant Darovasertib and Crizotinib in Participants With Primary Non-metastatic Uveal Melanoma

Who this might be right for
Uveal Melanoma
IDEAYA Biosciences 450
Early research (Phase 1)Study completedNCT01154218
What this trial is testing

Bioequivalence And Food Effect Study Comparing The Commercial Formulation Of Crizotinib To Its Clinical Study Formulations And Commercial Formulation With Or Without Food In Healthy Volunteers

Who this might be right for
Healthy
Pfizer 36
Large-scale testing (Phase 3)Active Not RecruitingNCT04603807
What this trial is testing

Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Hoffmann-La Roche 217
Post-approval studies (Phase 4)Ended earlyNCT03672643
What this trial is testing

Long Term Safety Observation of Crizotinib in Chinese NSCLC Population

Who this might be right for
ALK or ROS1-positive NSCLC
Pfizer 41
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