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Results for “Cutaneous Squamous Cell Carcinoma (CSCC)”

53 trials

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Showing 20 of 53 results

Early research (Phase 1)Not Yet RecruitingNCT07100925
What this trial is testing

Tolododekin Alfa (ANK-101) in Renal Allograft Recipients With High Risk Cutaneous Squamous Cell Carcinoma

Who this might be right for
Cutaneous Squamous Cell Carcinoma (CSCC)Renal TransplantSolid Tumor+1 more
Ankyra Therapeutics, Inc 20
Large-scale testing (Phase 3)Active Not RecruitingNCT06295809
What this trial is testing

(Neo)Adjuvant Intismeran Autogene (V940) and Pembrolizumab in Cutaneous Squamous Cell Carcinoma (V940-007)

Who this might be right for
Carcinoma, Squamous CellSkin Neoplasms
Merck Sharp & Dohme LLC 46
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06998342
What this trial is testing

MOHs Surgery and Short-Course Radiation Therapy With Structured Follow-Up for Head & Neck Squamous Cell Skin Cancer

Who this might be right for
Cutaneous Squamous Cell Carcinoma (CSCC)
University of Vermont Medical Center 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT03944941
What this trial is testing

Avelumab With or Without Cetuximab in Treating Patients With Advanced Skin Squamous Cell Cancer

Who this might be right for
Skin Squamous Cell CarcinomaMetastatic Skin Cancer
Alliance for Clinical Trials in Oncology 60
Testing effectiveness (Phase 2)Looking for participantsNCT07288073
What this trial is testing

TIL Therapy in cSCC and MCC

Who this might be right for
Cutaneous Squamous Cell CarcinomaMerkel Cell CarcinomaMetastatic Cutaneous Squamous Cell Carcinoma+1 more
Karam Khaddour, MD, MS 14
Early research (Phase 1)Active Not RecruitingNCT05827614
What this trial is testing

Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications

Who this might be right for
Triple Negative Breast Cancer (TNBC)High Grade Serous Ovarian CarcinomaHigh Grade Endometrial Carcinoma+9 more
Boundless Bio 85
Early research (Phase 1)Looking for participantsNCT04389632
What this trial is testing

Sigvotatug Vedotin in Advanced Solid Tumors

Who this might be right for
Carcinoma, Non-Small Cell LungSquamous Cell Carcinoma of Head and NeckHER2 Negative Breast Neoplasms+9 more
Seagen, a wholly owned subsidiary of Pfizer 1,006
Testing effectiveness (Phase 2)Looking for participantsNCT06823479
What this trial is testing

Towards Cure Via Only Ultra-short ICB in CSCC

Who this might be right for
Cutaneous Squamous Cell Carcinoma (CSCC)Cutaneous Squamous Cell CancerCutaneous Squamous Cell Carcinoma of the Head and Neck+1 more
The Netherlands Cancer Institute 41
Testing effectiveness (Phase 2)Looking for participantsNCT06580054
What this trial is testing

Pembrolizumab for the Treatment of Locally Advanced and/or Recurrent Orbital or Periocular Cutaneous Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and NeckRecurrent Cutaneous Squamous Cell Carcinoma of the Head and NeckStage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
University of Michigan Rogel Cancer Center 22
Testing effectiveness (Phase 2)Looking for participantsNCT05377905
What this trial is testing

Microneedle Array Plus Doxorubicin in Cutaneous Squamous Cell Cancer (cSCC)

Who this might be right for
Cutaneous Squamous Cell CarcinomaSkin Cancers - Squamous Cell Carcinoma
Falo, Louis, MD 48
Not applicableUnknownNCT05246228
What this trial is testing

Immune System Modulation and Outcome in High-risk cSCC Treated With Surgery and Radiotherapy

Who this might be right for
Squamous Cell Carcinoma of the Skin
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 42
Testing effectiveness (Phase 2)WithdrawnNCT06384820
What this trial is testing

Study of Cemiplimab Alone or in Combination With Fianlimab and/or Other Experimental Agents in Adult Participants With Peri-operative Stage III/IV Cutaneous Squamous Cell Carcinoma (CSCC)

Who this might be right for
Cutaneous Squamous Cell Carcinoma
Regeneron Pharmaceuticals
Testing effectiveness (Phase 2)Looking for participantsNCT05910827
What this trial is testing

Study of an Anti-HER3 Antibody, HMBD-001, With Docetaxel +/- Cetuximab in Advanced Squamous Non-small Cell Lung Cancers, and HMBD-001 + Cetuximab in Advanced Squamous Cell Cancers

Who this might be right for
Advanced or Metastatic Squamous Non-Small Cell Lung CancerAdvanced Head and Neck Squamous Cell CarcinomaAdvanced Esophageal Squamous Cell Carcinoma+2 more
Hummingbird Bioscience
Early research (Phase 1)Study completedNCT04160065
What this trial is testing

Immunotherapy With IFx-Hu2.0 Vaccine for Advanced Non-melanoma Skin Cancers

Who this might be right for
Merkel Cell CarcinomaCutaneous Squamous Cell CarcinomaNon-Melanoma Skin Cancers
TuHURA Biosciences, Inc. 23
Large-scale testing (Phase 3)Looking for participantsNCT06585410
What this trial is testing

Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma

Who this might be right for
Cutaneous Squamous Cell Carcinoma (CSCC)
Regeneron Pharmaceuticals 369
Testing effectiveness (Phase 2)Ended earlyNCT04799054
What this trial is testing

TransCon TLR7/8 Agonist With or Without Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorLocally Advanced Solid TumorMetastatic Solid Tumor+4 more
Ascendis Pharma Oncology Division A/S 188
Testing effectiveness (Phase 2)Active Not RecruitingNCT04808999
What this trial is testing

Neoadjuvant Study of PD-1 Inhibitor Pembrolizumab in PD-1 Naive Cutaneous Squamous Cell Carcinoma (cSCC)

Who this might be right for
Squamous Cell Carcinoma
Diwakar Davar 30
Testing effectiveness (Phase 2)Ended earlyNCT04812535
What this trial is testing

Non-comparative Study of IFX-1 Alone or IFX-1+Pembrolizumab in Patients With Locally Advanced or Metastatic cSCC.

Who this might be right for
SCC - Squamous Cell Carcinoma of Skin
InflaRx GmbH 30
Testing effectiveness (Phase 2)Looking for participantsNCT06041802
What this trial is testing

Pembrolizumab (+) Berahyaluronidase Alfa (MK-3475A) (Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180)) in Japanese Participants With Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma (R/M cSCC) or Locally Advanced (LA) Unresectable cSCC (MK-3475A-E39)

Who this might be right for
Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 19
Not applicableLooking for participantsNCT06875609
What this trial is testing

CtDNA in Cutaneous Squamous Cell Carcinoma

Who this might be right for
Cutaneous Squamous Cell Carcinoma
Massachusetts Eye and Ear Infirmary 60
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