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Results for “Cyclin-Dependent Kinase-Like 5 Deficiency Disorder”

26 trials

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Showing 20 of 26 results

Testing effectiveness (Phase 2)Study completedNCT05626634
What this trial is testing

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

Who this might be right for
Developmental and Epileptic EncephalopathyDravet SyndromeLennox-Gastaut Syndrome
Longboard Pharmaceuticals 41
Large-scale testing (Phase 3)Not Yet RecruitingNCT05249556
What this trial is testing

Double-blind, Randomized, Placebo-controlled Trial of Ganaxolone in CDKL5 Deficiency Patients 6 Months to Less Than 2 Years Old

Who this might be right for
CDKL5 Deficiency Disorder
Immedica Pharma AB 20
Not applicableLooking for participantsNCT05558371
What this trial is testing

International CDKL5 Clinical Research Network

Who this might be right for
CDKL5CDKL5 Deficiency DisorderCDD
University of Colorado, Denver 1,000
Large-scale testing (Phase 3)Study completedNCT03572933
What this trial is testing

Study of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency Disorder

Who this might be right for
CDKL5 Deficiency Disorder
Marinus Pharmaceuticals 101
Not applicableStudy completedNCT06447675
What this trial is testing

Efficacy and Safety Evaluation of Hyperthermic Baths in the Treatment of Seizures in CDKL5 Deficiency Disorder

Who this might be right for
CDKL5 Deficiency Disorder
Xuanwu Hospital, Beijing 8
Testing effectiveness (Phase 2)Study completedNCT03861871
What this trial is testing

Fenfluramine in CDKL5 Deficiency Disorder (CDD)

Who this might be right for
CDD
NYU Langone Health 7
Not applicableLooking for participantsNCT06448663
What this trial is testing

Targeting the Gut to Improve Seizure Control in CDKL5 Deficiency Disorder (CDD)

Who this might be right for
CDKL5
University of Milan 20
Not applicableNo Longer AvailableNCT04678479
What this trial is testing

Ganaxolone Expanded Access Program Compassionate Use

Who this might be right for
CDKL5 Disorder
Marinus Pharmaceuticals
Not applicableLooking for participantsNCT06585605
What this trial is testing

A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes

Who this might be right for
Epilepsy in ChildrenDyskinesiasMovement Disorders in Children+7 more
Boston Children's Hospital 500
Not applicableTemporarily pausedNCT04486768
What this trial is testing

International CDKL5 Registry

Who this might be right for
CDKL5 Deficiency Disorder (CDD)
University of Pennsylvania 500
Not applicableStudy completedNCT02738281
What this trial is testing

Natural History of Rett Syndrome & Related Disorders

Who this might be right for
Rett SyndromeMECP2 Duplication dIsorderCDKL5 Disorder+1 more
University of Alabama at Birmingham 1,044
Testing effectiveness (Phase 2)Study completedNCT05364021
What this trial is testing

Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies

Who this might be right for
Developmental and Epileptic EncephalopathyDravet SyndromeLennox Gastaut Syndrome
Longboard Pharmaceuticals 52
Testing effectiveness (Phase 2)Study completedNCT03650452
What this trial is testing

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Participants With Developmental and/or Epileptic Encephalopathies

Who this might be right for
EpilepsyDravet SyndromeLennox-Gastaut Syndrome
Takeda 141
Not applicableActive Not RecruitingNCT05373719
What this trial is testing

Observational Study in Patients With Cyclin-dependent Kinase-like 5 Deficiency Disorder

Who this might be right for
Cyclin-Dependent Kinase-Like 5 Deficiency Disorder
Loulou Foundation 112
Not applicableStudy completedNCT00299312
What this trial is testing

Genetic and Physical Characteristics of Rett Syndrome

Who this might be right for
Rett SyndromeMECP2 Duplication DisorderRett-related Disorder
University of Alabama at Birmingham 10
Not applicableEnded earlyNCT04537832
What this trial is testing

Natural History Study of Infants and Children With Developmental and Epileptic Encephalopathies

Who this might be right for
Dravet Syndrome
Encoded Therapeutics 58
Large-scale testing (Phase 3)Study completedNCT02318602
What this trial is testing

Cannabidiol Oral Solution as an Adjunctive Treatment for Treatment-resistant Seizure Disorder

Who this might be right for
Seizures
INSYS Therapeutics Inc 52
Not applicableAvailableNCT06149663
What this trial is testing

Intermediate-Size Expanded Access Protocol (EAP) for LP352

Who this might be right for
Dravet SyndromeLennox Gastaut SyndromeDevelopmental and Epileptic Encephalopathies
Longboard Pharmaceuticals
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Not applicableLooking for participantsNCT06967727
What this trial is testing

Registry and Natural History of Epilepsy-Dyskinesia Syndromes

Who this might be right for
Epilepsy-DyskinesiaEpilepsyDyskinesia+11 more
Boston Children's Hospital 700
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