Testing effectiveness (Phase 2)Study completedNCT03861871What this trial is testingFenfluramine in CDKL5 Deficiency Disorder (CDD)Who this might be right forCDD NYU Langone Health 7
Not applicableStudy completedNCT06447675What this trial is testingEfficacy and Safety Evaluation of Hyperthermic Baths in the Treatment of Seizures in CDKL5 Deficiency DisorderWho this might be right forCDKL5 Deficiency Disorder Xuanwu Hospital, Beijing 8
Testing effectiveness (Phase 2)Study completedNCT03694275What this trial is testingA Multicenter, Open-label, Pilot Study of Soticlestat (TAK-935/OV935) in Participants With 15Q Duplication Syndrome (Dup 15q) or Cyclin-Dependent Kinase-Like 5 (CDKL5) Deficiency Disorder (ARCADE STUDY)Who this might be right for15q Duplication SyndromeCDKL5 Deficiency Disease Takeda 20
Testing effectiveness (Phase 2)Study completedNCT05626634What this trial is testingOpen-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic EncephalopathyWho this might be right forDevelopmental and Epileptic EncephalopathyDravet SyndromeLennox-Gastaut Syndrome Longboard Pharmaceuticals 41
Not applicableLooking for participantsNCT06448663What this trial is testingTargeting the Gut to Improve Seizure Control in CDKL5 Deficiency Disorder (CDD)Who this might be right forCDKL5 University of Milan 20
Testing effectiveness (Phase 2)Study completedNCT03650452What this trial is testingA Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Participants With Developmental and/or Epileptic EncephalopathiesWho this might be right forEpilepsyDravet SyndromeLennox-Gastaut Syndrome Takeda 141
Not applicableLooking for participantsNCT05635266What this trial is testingTissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research InitiativesWho this might be right forAge-Related Macular DegenerationAllergiesAlpha-Gal Syndrome+44 more Sanguine Biosciences 20,000
Not applicableLooking for participantsNCT04486768What this trial is testingInternational CDKL5 RegistryWho this might be right forCDKL5 Deficiency Disorder (CDD) University of Pennsylvania 500
Large-scale testing (Phase 3)Study completedNCT03572933What this trial is testingStudy of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency DisorderWho this might be right forCDKL5 Deficiency Disorder Marinus Pharmaceuticals 101
Testing effectiveness (Phase 2)Ended earlyNCT03635073What this trial is testingSoticlestat in Adults and Children With Rare EpilepsiesWho this might be right forEpilepsyDravet Syndrome (DS)Lennox-Gastaut Syndrome (LGS) Takeda 156
Not applicableActive Not RecruitingNCT05373719What this trial is testingObservational Study in Patients With Cyclin-dependent Kinase-like 5 Deficiency DisorderWho this might be right forCyclin-Dependent Kinase-Like 5 Deficiency Disorder Loulou Foundation 112
Large-scale testing (Phase 3)Study completedNCT02318602What this trial is testingCannabidiol Oral Solution as an Adjunctive Treatment for Treatment-resistant Seizure DisorderWho this might be right forSeizures INSYS Therapeutics Inc 52
Not applicableLooking for participantsNCT06585605What this trial is testingA Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia SyndromesWho this might be right forEpilepsy in ChildrenDyskinesiasMovement Disorders in Children+7 more Boston Children's Hospital 500
Not applicableStudy completedNCT06663163What this trial is testingThe Association Between Fever and CDKL5 Deficiency Disorder: a Nationwide SurveyWho this might be right forCDKL5 Deficiency Disorder Xuanwu Hospital, Beijing 131
Not applicableNo Longer AvailableNCT04678479What this trial is testingGanaxolone Expanded Access Program Compassionate UseWho this might be right forCDKL5 Disorder Marinus Pharmaceuticals
Not applicableEnrolling By InvitationNCT03655223What this trial is testingEarly Check: Expanded Screening in NewbornsWho this might be right forSpinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more RTI International 30,000
Large-scale testing (Phase 3)Not Yet RecruitingNCT05249556What this trial is testingDouble-blind, Randomized, Placebo-controlled Trial of Ganaxolone in CDKL5 Deficiency Patients 6 Months to Less Than 2 Years OldWho this might be right forCDKL5 Deficiency Disorder Immedica Pharma AB 20
Not applicableLooking for participantsNCT05558371What this trial is testingInternational CDKL5 Clinical Research NetworkWho this might be right forCDKL5CDKL5 Deficiency DisorderCDD University of Colorado, Denver 1,000
Testing effectiveness (Phase 2)Study completedNCT05364021What this trial is testingStudy to Investigate LP352 in Subjects With Developmental and Epileptic EncephalopathiesWho this might be right forDevelopmental and Epileptic EncephalopathyDravet SyndromeLennox Gastaut Syndrome Longboard Pharmaceuticals 52
Not applicableLooking for participantsNCT06967727What this trial is testingRegistry and Natural History of Epilepsy-Dyskinesia SyndromesWho this might be right forEpilepsy-DyskinesiaEpilepsyDyskinesia+11 more Boston Children's Hospital 700