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Results for “Cyclophosphamide Reduced-dose”

18 trials

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Showing 18 of 18 results

Large-scale testing (Phase 3)UnknownNCT06000982
What this trial is testing

Comparison of Different Dose of Post-transplantation Cyclophosphamide as Graft Versus Host Disease Prophylaxis

Who this might be right for
GVHD
Shanghai Jiao Tong University School of Medicine 138
Testing effectiveness (Phase 2)Active Not RecruitingNCT06001385
What this trial is testing

HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAcute Leukemia+8 more
Center for International Blood and Marrow Transplant Research 313
Testing effectiveness (Phase 2)UnknownNCT06255847
What this trial is testing

Clinical Study of Reduced-dose Pomalidomide and Cyclophosphamide Combined With Dexamethasone in the Treatment of Patients With Debilitating RRMM

Who this might be right for
Multiple Myeloma in Relapse
Shanxi Bethune Hospital 43
Testing effectiveness (Phase 2)Active Not RecruitingNCT05621759
What this trial is testing

Cyclophosphamide, Abatacept, and Tacrolimus for the Prevention of GvHD

Who this might be right for
Graft Vs Host Disease
NYU Langone Health 27
Testing effectiveness (Phase 2)Looking for participantsNCT06695741
What this trial is testing

Reduced Dose of Cyclophosphamide Combined With Standard Immunosuppressive Therapy to Treat Severe Aplastic Anemia

Who this might be right for
Severe Aplastic AnemiaCyclophosphamide Reduced-doseImmunosuppressive Therapy
Institute of Hematology & Blood Diseases Hospital, China 75
Testing effectiveness (Phase 2)Study completedNCT03128359
What this trial is testing

High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplant

Who this might be right for
Acute LeukemiaChronic Lymphocytic Leukemia/Small Lymphocytic LymphomaChronic Myelogenous Leukemia, BCR-ABL1 Positive+12 more
City of Hope Medical Center 38
Large-scale testing (Phase 3)Not Yet RecruitingNCT07193420
What this trial is testing

Reduced Post-transplant Cyclophosphamide Dose in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplantation for Hematological Malignancies

Who this might be right for
GVHD - Graft-Versus-Host DiseaseHSCTHaploidentical Stem Cell Transplantation
Assistance Publique - Hôpitaux de Paris 180
Testing effectiveness (Phase 2)Ended earlyNCT01135329
What this trial is testing

Reduced-intensity, Related-donor Bone Marrow Transplantation Followed by High-dose Cyclophosphamide for Hematologic Cancers

Who this might be right for
LymphomaLeukemiaMyelodysplastic Syndrome
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 15
Testing effectiveness (Phase 2)Looking for participantsNCT06984536
What this trial is testing

Reduced ATG Plus Mini PTCy for GVHD Prophylaxis in Haplo-SCT

Who this might be right for
Myelodysplastic SyndromeAcute Leukemia
Peking University People's Hospital 40
Testing effectiveness (Phase 2)Study completedNCT06151847
What this trial is testing

Lifileucel With Reduced Dose Fludarabine/Cyclophosphamide Lymphodepletion and Interleukin-2 for the Treatment of Patients With Unresectable or Metastatic Melanoma

Who this might be right for
Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic MelanomaPathologic Stage IIIC Cutaneous Melanoma AJCC v8+1 more
University of Kansas Medical Center 11
Testing effectiveness (Phase 2)Study completedNCT01860170
What this trial is testing

Post-Transplant Bortezomib and High Dose Cyclophosphamide as Graft-Versus-Host Disease (GVHD) Prophylaxis

Who this might be right for
Hematological Malignancy
Corewell Health West 28
Not applicableUnknownNCT05780554
What this trial is testing

Post-transplantation Cyclophosphamide in Haploidentical Stem Cell Allografts Dose Reduction: 50 mg/kg vs 25 mg/kg

Who this might be right for
Graft Vs Host Disease
Centro de Hematología y Medicina Interna 42
Testing effectiveness (Phase 2)Ended earlyNCT03263767
What this trial is testing

Post Transplant Cyclophosphamide (PTCY) as Sole Graft Versus Host Disease (GVHD) Prophylaxis for Matched Allotransplant: CYRIC

Who this might be right for
Graft Versus Host Disease
Nantes University Hospital 47
Testing effectiveness (Phase 2)Looking for participantsNCT07719946
What this trial is testing

To Study Lower Dose of Cyclophosphamide After Stem Cell Transplant for Blood Cancers

Who this might be right for
Haploidentical Hematopoietic Stem Cell TransplantHematological Malignancies
Tata Memorial Centre 20
Testing effectiveness (Phase 2)Looking for participantsNCT05436418
What this trial is testing

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Who this might be right for
Peripheral Blood Stem Cell TransplantationHematopoietic Stem Cell Transplantation
National Cancer Institute (NCI) 260
Testing effectiveness (Phase 2)Looking for participantsNCT06042569
What this trial is testing

Dose-Reduced Docetaxel With Cyclophosphamide for the Treatment of Vulnerable Older Women With Stage I-III HER2 Negative Breast Cancer, the DOROTHY Trial

Who this might be right for
Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8+1 more
City of Hope Medical Center 174
Large-scale testing (Phase 3)Looking for participantsNCT06705062
What this trial is testing

Study Comparing Reduced Versus Standard Dose Post-transplantation Cyclophosphamide in Combination With Post-engraftment Anti-thymoglobin as Graft Versus Host Disease Prophylaxis in Alternative Donor Peripheral Stem Cell Transplantation

Who this might be right for
Allogeneic Hematopoietic Cell TransplantGraft Versus Host Disease
Shanghai Jiao Tong University School of Medicine 316
Testing effectiveness (Phase 2)Active Not RecruitingNCT03821610
What this trial is testing

A Comparison of Reduced Dose Total Body Irradiation (TBI) and Cyclophosphamide With Fludarabine and Melphalan Reduced Intensity Conditioning in Adults With Acute Lymphoblastic Leukaemia (ALL) in Complete Remission. (ALL-RIC)

Who this might be right for
Acute Lymphoblastic Leukemia
University of Birmingham 242