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Results for “Cystic Fibrosis, Homozygous for the F508del CFTR Mutation”

Showing 13 of 0 results

Large-scale testing (Phase 3)Study completedNCT03125395
What this trial is testing

A Rollover Safety Study of Lumacaftor/Ivacaftor in Subjects Aged 2 Years and Older With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 57
Testing effectiveness (Phase 2)Ended earlyNCT02649751
What this trial is testing

Evaluation of (R)-Roscovitine Safety and Effects in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation

Who this might be right for
Cystic Fibrosis
University Hospital, Brest 49
Large-scale testing (Phase 3)Study completedNCT02514473
What this trial is testing

Evaluate the Efficacy and Safety of Lumacaftor in Combination With Ivacaftor in Subjects With CF, Homozygous for the F508del-CFTR Mutation

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 206
Early research (Phase 1)Study completedNCT02275936
What this trial is testing

Study of N91115 in Patients With Cystic Fibrosis Homozygous F508del-CFTR Mutation

Who this might be right for
Cystic Fibrosis
Nivalis Therapeutics, Inc. 51
Large-scale testing (Phase 3)Study completedNCT02544451
What this trial is testing

Rollover Study to Evaluate the Safety and Efficacy of Long-term Treatment With Lumacaftor in Combination With Ivacaftor

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 246
Testing effectiveness (Phase 2)Study completedNCT02508207
What this trial is testing

Evaluate Effects of VX-661/Ivacaftor on Lung and Extrapulmonary Systems in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 34
Testing effectiveness (Phase 2)Temporarily pausedNCT03756922
What this trial is testing

A DDI Study of FDL169 and FDL176 in Healthy Subjects

Who this might be right for
Cystic Fibrosis
Flatley Discovery Lab LLC 78
Large-scale testing (Phase 3)Study completedNCT03537651
What this trial is testing

Evaluate the Safety and Efficacy of Long-term Treatment With TEZ/IVA in CF Participants With an F508del CFTR Mutation

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 130
Large-scale testing (Phase 3)Study completedNCT03150719
What this trial is testing

Evaluate Safety, Efficacy, and Tolerability of TEZ/IVA in Orkambi® (Lumacaftor/Ivacaftor) -Experienced Subjects With Cystic Fibrosis (CF)

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 98
Large-scale testing (Phase 3)Study completedNCT02797132
What this trial is testing

Safety and Pharmacokinetic Study of Lumacaftor/Ivacaftor in Subjects Aged 2 Through 5 Years With Cystic Fibrosis, Homozygous for F508del

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 62
Testing effectiveness (Phase 2)Study completedNCT00865904
What this trial is testing

Study of VX-809 in Cystic Fibrosis Subjects With the ∆F508-CFTR Gene Mutation

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 93
Testing effectiveness (Phase 2)Study completedNCT01531673
What this trial is testing

Study of VX-661 Alone and in Combination With Ivacaftor in Subjects Homozygous or Heterozygous to the F508del-Cystic Fibrosis Transmembrane Conductance Regulator(CFTR) Mutation

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 194
Large-scale testing (Phase 3)Study completedNCT01807949
What this trial is testing

Lumacaftor in Combination With Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Who Are Homozygous for the F508del-CFTR Mutation

Who this might be right for
Cystic Fibrosis, Homozygous for the F508del CFTR Mutation
Vertex Pharmaceuticals Incorporated 563

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