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Results for “Cytochrome P-450”

258 trials

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Showing 20 of 258 results

Post-approval studies (Phase 4)Study completedNCT01778907
What this trial is testing

Cytochrome P450-2D6 Screening Among Elderly Using Antidepressants (CYSCE)

Who this might be right for
DepressionDepressive DisorderPoor Metabolizer Due to Cytochrome P450 CYP2D6 Variant+2 more
University of Groningen 202
Not applicableUnknownNCT00162383
What this trial is testing

Metabolic Capacity of Israeli Populations

Who this might be right for
Healthy Volunteers
Hadassah Medical Organization 1,200
Early research (Phase 1)Study completedNCT04268394
What this trial is testing

Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677

Who this might be right for
Healthy Volunteer
Celgene 48
Early research (Phase 1)Study completedNCT01323465
What this trial is testing

Study to Evaluate the Effect of Rifampicin, Ketoconazole, and Omeprazole on the Pharmacokinetics of Sativex

Who this might be right for
Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Known Inducer of CYP3A4Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Potent Inhibitor of CYP3A4Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a CYP2C19 Inhibitor
Jazz Pharmaceuticals
Testing effectiveness (Phase 2)WithdrawnNCT05545319
What this trial is testing

Learn About the Medicine Called Nirmatrelvir Used in Combination With Ritonavir in People With Weakened Immune Systems or at Increased Risk for Poor Outcomes Who Are Hospitalized Due to Severe COVID-19

Who this might be right for
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)Coronavirus Disease 2019 (COVID-19)Immunocompromised+2 more
Pfizer
Early research (Phase 1)Study completedNCT02365571
What this trial is testing

LY3154207 in Healthy Participants

Who this might be right for
Healthy Participants
Eli Lilly and Company 64
Post-approval studies (Phase 4)Study completedNCT04182191
What this trial is testing

Influence of CYP2C9 Genotype on Clinical Efficacy of Tenoxicam

Who this might be right for
Molar, ThirdPain
University of Sao Paulo 89
Early research (Phase 1)Study completedNCT03103568
What this trial is testing

Investigate the Potential Influence of Nitisinone on the Metabolism and the Transport of Other Drugs in Healthy Volunteers

Who this might be right for
Drug Drug Interaction
Swedish Orphan Biovitrum 36
Not applicableStudy completedNCT00992420
What this trial is testing

Genotype Information and Functional Testing Study

Who this might be right for
Coronary Artery Disease
Scripps Health 2,000
Not applicableStudy completedNCT06756620
What this trial is testing

Investigation of the Etiology of Hypertension and Endothelial Damage in Patients With Cytochrome P450 Oxidoreductase Deficiency

Who this might be right for
Cytochrome P450 Oxidoreductase DeficiencyHypertensionEndothelial Dysfunction+1 more
Ozge Bayrak Demirel 51
Not applicableStudy completedNCT02191358
What this trial is testing

YouScript IMPACT Registry

Who this might be right for
Adverse Drug EventsAdverse Drug ReactionsDrug Interaction Potentiation+10 more
Genelex Corporation 800
Not applicableStudy completedNCT01258504
What this trial is testing

Influence of CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Bosentan

Who this might be right for
Drug Interactions
Gerd Mikus 13
Early research (Phase 1)Study completedNCT00011635
What this trial is testing

The Effect of Milk Thistle on the Pharmacokinetics of Indinavir

Who this might be right for
HIV InfectionHealthy
National Institutes of Health Clinical Center (CC) 20
Early research (Phase 1)Study completedNCT02647086
What this trial is testing

Open Label, Drug-Drug Interaction (DDI) Study of Dupilumab (REGN668/SAR231893) in Patients With Moderate to Severe Atopic Dermatitis (AD)

Who this might be right for
Atopic Dermatitis
Regeneron Pharmaceuticals 14
Early research (Phase 1)Study completedNCT00803673
What this trial is testing

A Healthy Volunteer Study With Inhaled GSK573719 and Placebo

Who this might be right for
Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline 36
Early research (Phase 1)Study completedNCT03535662
What this trial is testing

A Pharmacokinetic Study of the Effect of Itraconazole Exposure to Orvepitant in Healthy Volunteers

Who this might be right for
Pharmacokinetic Study in Healthy Male Volunteers
Nerre Therapeutics Ltd. 16
Very early researchStudy completedNCT05891119
What this trial is testing

Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis

Who this might be right for
Atopic Dermatitis
Amgen 21
Not applicableStudy completedNCT03337945
What this trial is testing

In Vivo Determination of Cytochrome P450 Activities in Patients With Liver Cirrhosis

Who this might be right for
Liver Cirrhosis
University Hospital, Basel, Switzerland 48
Not applicableStudy completedNCT01944436
What this trial is testing

A Genetic and Perfusion Study of Response to Cognitive Enhancers in Lewy Body Disease

Who this might be right for
Lewy Body Disease
Sunnybrook Health Sciences Centre 57
Early research (Phase 1)Study completedNCT00696566
What this trial is testing

Healthy Volunteer Study of Clopidogrel and Rifampicin

Who this might be right for
Coronary Artery Disease
Sheffield Teaching Hospitals NHS Foundation Trust 12
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