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Results for “Cytochrome P-450”

259 trials

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Showing 20 of 259 results

Early research (Phase 1)Study completedNCT02774902
What this trial is testing

TAK-438_110 Drug Interaction With Cytochrome P450 3A4 (CYP3A4) Inhibitor Clarithromycin

Who this might be right for
Healthy Volunteers
Takeda 16
Early research (Phase 1)Study completedNCT01984229
What this trial is testing

The Effects of Posaconazole on Alectinib (RO5424802) Pharmacokinetics in Healthy Volunteers

Who this might be right for
Healthy Volunteer
Hoffmann-La Roche 23
Early research (Phase 1)Study completedNCT03258372
What this trial is testing

Crossover Drug-Drug Interaction Study to Determine Effects of Cytochrome P450 3A on Exposure to Mifepristone and Its Metabolites

Who this might be right for
Healthy
Corcept Therapeutics 48
Early research (Phase 1)Study completedNCT05175352
What this trial is testing

A Study Evaluating Potential Disease-Mediated Drug-Drug Interaction in Adult Participants With Active Eosinophilic Esophagitis Receiving Cendakimab

Who this might be right for
Eosinophilic Esophagitis
Celgene 16
Not applicableStudy completedNCT00023114
What this trial is testing

P450 Mediated Lung Toxicity

Who this might be right for
Pulmonary Disease
National Institute of Environmental Health Sciences (NIEHS) 10
Early research (Phase 1)Looking for participantsNCT07242781
What this trial is testing

Evaluate the Effect of Itraconazole and Rifampin on the Drug Levels of AR-LDD (BMS-986365) in Healthy Adult Male Participants

Who this might be right for
Healthy Volunteers
Celgene 42
Early research (Phase 1)Study completedNCT01323465
What this trial is testing

Study to Evaluate the Effect of Rifampicin, Ketoconazole, and Omeprazole on the Pharmacokinetics of Sativex

Who this might be right for
Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Known Inducer of CYP3A4Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Potent Inhibitor of CYP3A4Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a CYP2C19 Inhibitor
Jazz Pharmaceuticals
Not applicableUnknownNCT00945867
What this trial is testing

Cytochrome P450 2D6 (CYP 450 2D6) Genotype and Flecainide Efficacy

Who this might be right for
Atrial Fibrillation
Assaf-Harofeh Medical Center 100
Early research (Phase 1)Study completedNCT00859352
What this trial is testing

AZD1981 Midazolam CYP4503A Induction Study

Who this might be right for
Healthy Male Volunteer
AstraZeneca 28
Early research (Phase 1)Study completedNCT00696566
What this trial is testing

Healthy Volunteer Study of Clopidogrel and Rifampicin

Who this might be right for
Coronary Artery Disease
Sheffield Teaching Hospitals NHS Foundation Trust 12
Early research (Phase 1)Study completedNCT05084651
What this trial is testing

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Itraconazole

Who this might be right for
Malaria
Novartis Pharmaceuticals 19
Early research (Phase 1)Study completedNCT00509431
What this trial is testing

Erlotinib and Sirolimus in Treating Patients With Recurrent Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Jonsson Comprehensive Cancer Center 19
Early research (Phase 1)Study completedNCT01289756
What this trial is testing

Influence of Pharmacogenetic Factors, Paroxetine and Clarithromycin on Pharmacokinetics of Clomiphene

Who this might be right for
AnovulationDisorder Due Cytochrome P450 CYP2D6 VariantCytochrome P450 CYP3A Enzyme Deficiency
Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF) 20
Early research (Phase 1)Study completedNCT02993471
What this trial is testing

Ixekizumab in Participants With Plaque Psoriasis

Who this might be right for
Psoriasis
Eli Lilly and Company 28
Early research (Phase 1)Study completedNCT00443170
What this trial is testing

A Placebo-controlled Study to Investigate the Safety, and Pharmacokinetics of Oral GSK626616AC in Healthy Subjects

Who this might be right for
Healthy SubjectsAnaemia
GlaxoSmithKline 90
Early research (Phase 1)Study completedNCT05657613
What this trial is testing

Drug-Drug Interaction Study of Pacritinib and CYP450,Transporter Substrates, and CYP450 3A4 in Healthy Male Subjects

Who this might be right for
Drug Interactions
CTI BioPharma 60
Early research (Phase 1)Study completedNCT03234699
What this trial is testing

Assess the Influence of Cenobamate on the PK of Cytochrome P450 (CYP) Probe Drugs As a Means of Predicting Drug-drug Interactions

Who this might be right for
Healthy
SK Life Science, Inc. 24
Early research (Phase 1)Study completedNCT05304533
What this trial is testing

Assess the Drug Interaction Between MYK-224 and Itraconazole and Verapamil in Healthy Participants

Who this might be right for
Healthy Participants
Bristol-Myers Squibb 45
Early research (Phase 1)Study completedNCT04268394
What this trial is testing

Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677

Who this might be right for
Healthy Volunteer
Celgene 48
Post-approval studies (Phase 4)Study completedNCT00872599
What this trial is testing

The Effect of a Peroxisome Proliferator-activated Receptor (PPAR) Alpha Agonist on Cytochrome P450 (CYP) Monooxygenase Activity in Humans

Who this might be right for
Hypertension
Vanderbilt University 75
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