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Results for “Cytochrome P-450”

258 trials

Showing 20 of 258 results

Not applicableUnknownNCT05210153
What this trial is testing

Personalized Sertraline Dosing in Patients With Depression

Who this might be right for
Depressive Disorder, Major
University of Belgrade 148
Early research (Phase 1)Study completedNCT00741468
What this trial is testing

Open-Label, Multiple-Dose, Non-Randomized Study to Assess Drug-Drug Interactions of Proellex® in Female Subjects

Who this might be right for
Drug Interactions
Repros Therapeutics Inc. 18
Early research (Phase 1)Study completedNCT03259542
What this trial is testing

Mifepristone Drug-Drug Interaction Study With CYP3A Inhibitor

Who this might be right for
Drug Interaction PotentiationHealthy
Corcept Therapeutics 33
Early research (Phase 1)Study completedNCT02251132
What this trial is testing

Pharmacokinetics of Tipranavir Soft Elastic Capsules (SEDDS) and Ritonavir and Their Effects on Cytochrome P-450 (3A4) in Healthy Volunteers

Who this might be right for
Healthy
Boehringer Ingelheim 113
Not applicableStudy completedNCT03859622
What this trial is testing

CYP2D6 Polymorphism in Patients of General Practice in Austria

Who this might be right for
Disorder Due Cytochrome P450 CYP2D6 Variant
Karl Landsteiner Institute for Systematics in General Medicine 289
Early research (Phase 1)Study completedNCT03258372
What this trial is testing

Crossover Drug-Drug Interaction Study to Determine Effects of Cytochrome P450 3A on Exposure to Mifepristone and Its Metabolites

Who this might be right for
Healthy
Corcept Therapeutics 48
Early research (Phase 1)Study completedNCT03990129
What this trial is testing

Pharmacokinetic Interactions of Metamizole (Dipyrone) in Healthy Subjects

Who this might be right for
InhibitionInductionDrug-Drug Interaction
University Hospital, Basel, Switzerland 12
Early research (Phase 1)Study completedNCT05712265
What this trial is testing

Study to Evaluate the Effects of a Cytochrome P450 2C19 Inhibitor on the Pharmacokinetics of Miricorilant

Who this might be right for
Antipsychotic Induced Weight GainNon-alcoholic Steatohepatitis (NASH)
Corcept Therapeutics 26
Early research (Phase 1)Study completedNCT06547164
What this trial is testing

Investigate the Pharmacokinetics of Midazolam After Repeated Doses of Camizestrant (AZD9833) and to Investigate the Pharmacokinetics of Camizestrant When Administered Alone and in Combination With Carbamazepine in Healthy Post-Menopausal Female Participants

Who this might be right for
Healthy Participants
AstraZeneca 40
Early research (Phase 1)Study completedNCT03072056
What this trial is testing

A Pharmacokinetic Study of MIN-101 and Its Metabolites in Healthy Subjects to Compare MIN-101 in Poor and Extensive Metabolizers

Who this might be right for
Healthy Subjects
Minerva Neurosciences 23
Not applicableStudy completedNCT00834353
What this trial is testing

Prospective Study of N-acetyltransferase2 (NAT2) and Cytochrome P4502E1 (CYP2E1) Gene as Susceptible Risk Factors for Antituberculosis (ATT) Induced Hepatitis

Who this might be right for
Pulmonary Tuberculosis
Maulana Azad Medical College
Early research (Phase 1)Study completedNCT01934569
What this trial is testing

Drug-Drug Interaction Study With PF-05089771

Who this might be right for
Healthy
Pfizer 17
Early research (Phase 1)Study completedNCT02243553
What this trial is testing

Effects of Tipranavir (With Ritonavir) Capsule and Liquid Formulation on Cytochrome P450 and P-glycoprotein Activity in Healthy Volunteers

Who this might be right for
Healthy
Boehringer Ingelheim 34
Post-approval studies (Phase 4)Ended earlyNCT02483598
What this trial is testing

Mechanistic Investigation Of Intestinal Cytochrome p450 3A4 Following Roux-en-Y Surgery And Its Effect on Plasma Concentrations of Buspirone

Who this might be right for
Gastric Bypass
North Dakota State University 12
Very early researchStudy completedNCT05891119
What this trial is testing

Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis

Who this might be right for
Atopic Dermatitis
Amgen 21
Early research (Phase 1)Study completedNCT01731067
What this trial is testing

Cocktail Approach for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood Spot

Who this might be right for
Healthy Volunteers
Jules Desmeules 10
Early research (Phase 1)Study completedNCT02772601
What this trial is testing

This Study Tests the Effect of Risankizumab on the Metabolism in the Liver of Five Additional Drugs to Study Possible Drug Interactions in Patients With Psoriasis With or Without Psoriatic Arthritis

Who this might be right for
Psoriasis
AbbVie 21
Early research (Phase 1)Looking for participantsNCT07014930
What this trial is testing

Identification of New Tools for Predicting Natural Metabolic Performance of the Liver

Who this might be right for
Healthy Volunteers
Caroline Samer 40
Early research (Phase 1)Study completedNCT05657613
What this trial is testing

Drug-Drug Interaction Study of Pacritinib and CYP450,Transporter Substrates, and CYP450 3A4 in Healthy Male Subjects

Who this might be right for
Drug Interactions
CTI BioPharma 60
Early research (Phase 1)Ended earlyNCT04959266
What this trial is testing

Assess the Effects of Itraconazole, Rifampicin, and Omeprazole on Pharmacokinetics of Adavosertib

Who this might be right for
Advanced Solid Tumours
AstraZeneca 5
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