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Results for “Cytochrome P-450”

263 trials

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Showing 20 of 263 results

Early research (Phase 1)Study completedNCT03340662
What this trial is testing

Study Evaluating the Effects of Food, Cytochrome P450 Inhibition and Induction on the Pharmacokinetics of CC-122

Who this might be right for
Healthy Volunteer
Celgene 81
Post-approval studies (Phase 4)Study completedNCT01778907
What this trial is testing

Cytochrome P450-2D6 Screening Among Elderly Using Antidepressants (CYSCE)

Who this might be right for
DepressionDepressive DisorderPoor Metabolizer Due to Cytochrome P450 CYP2D6 Variant+2 more
University of Groningen 202
Not applicableStudy completedNCT00072644
What this trial is testing

Pharmacokinetic Interactions With Prednisolone in Healthy Volunteers and HIV-infected Patients Receiving Single-Dose Prednisone

Who this might be right for
Healthy
National Institutes of Health Clinical Center (CC) 75
Post-approval studies (Phase 4)Study completedNCT02247128
What this trial is testing

Antiplatelet Therapy for Patients Undergoing Transcatheter Aortic Valve Implantation

Who this might be right for
Aortic Valve DiseaseMyocardial InfarctionStroke+1 more
St. Antonius Hospital 1,016
Early research (Phase 1)Study completedNCT04059367
What this trial is testing

Research Study to Investigate How a Study Medicine (NNC9204- 1177) Affects Blood Levels of Other Medicines in Healthy People

Who this might be right for
Healthy VolunteersOverweightObesity
Novo Nordisk A/S 45
Early research (Phase 1)Study completedNCT02774902
What this trial is testing

TAK-438_110 Drug Interaction With Cytochrome P450 3A4 (CYP3A4) Inhibitor Clarithromycin

Who this might be right for
Healthy Volunteers
Takeda 16
Post-approval studies (Phase 4)Study completedNCT00629122
What this trial is testing

Pharmacokinetics of Sublingual Versus Oral Tacrolimus in Patients Awaiting Kidney Transplantation

Who this might be right for
Kidney Failure, Chronic
Weill Medical College of Cornell University 5
Early research (Phase 1)Study completedNCT04268394
What this trial is testing

Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677

Who this might be right for
Healthy Volunteer
Celgene 48
Early research (Phase 1)Study completedNCT03624959
What this trial is testing

Drug-drug Interaction Study of Ozanimod With Inhibitor or Inducer of CYP2C8 and/or CYP3A

Who this might be right for
Healthy Volunteer
Celgene 100
Early research (Phase 1)Study completedNCT03512548
What this trial is testing

Study in Healthy Subjects to Determine the Effect of an Inhibitor on Exposure to Relacorilant and Its Metabolites

Who this might be right for
Healthy
Corcept Therapeutics 52
Early research (Phase 1)Study completedNCT00509431
What this trial is testing

Erlotinib and Sirolimus in Treating Patients With Recurrent Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Jonsson Comprehensive Cancer Center 19
Early research (Phase 1)Study completedNCT02243553
What this trial is testing

Effects of Tipranavir (With Ritonavir) Capsule and Liquid Formulation on Cytochrome P450 and P-glycoprotein Activity in Healthy Volunteers

Who this might be right for
Healthy
Boehringer Ingelheim 34
Post-approval studies (Phase 4)Study completedNCT03204578
What this trial is testing

Physiological Study of the Human CYP3A Activity (PiSA)

Who this might be right for
Cytochrome P450 CYP3A Enzyme Deficiency
University Hospital, Basel, Switzerland 12
Early research (Phase 1)Study completedNCT03789890
What this trial is testing

Study to Learn More About the Effect of Itraconazole (ITZ) Given Repeatedly by Mouth on the Way How the Study Drug BAY1902607 Given One Time by Mouth Acts in the Human Body of Healthy Male Participants

Who this might be right for
Drug Interactions
Bayer 14
Early research (Phase 1)Study completedNCT03547024
What this trial is testing

A Study in Healthy Participants to Evaluate the Effects of Multiple Doses of JNJ-55308942 on Cytochrome P450 Substrate Activity and on the Pharmacokinetics of Levonorgestrel/Ethinyl Estradiol

Who this might be right for
Healthy
Janssen-Cilag International NV 14
Early research (Phase 1)Study completedNCT04525235
What this trial is testing

Phenotyping of High Dose Rifampicin

Who this might be right for
Tuberculosis
Radboud University Medical Center 25
Early research (Phase 1)Study completedNCT02211079
What this trial is testing

Assess Effect of JNJ-54861911 on Pharmacokinetics of Cocktail Representatives for Cytochrome P450 (CYP) 3A4, CYP2B6, CYP2C9, and CYP1A2 Substrates

Who this might be right for
Healthy
Janssen Research & Development, LLC 16
Not applicableStudy completedNCT00122889
What this trial is testing

Effects of Garlic Supplements on Drug Metabolism

Who this might be right for
Healthy
Fred Hutchinson Cancer Center 80
Early research (Phase 1)Study completedNCT01273168
What this trial is testing

Endoxifen in Adults With Hormone Receptor Positive Solid Tumors

Who this might be right for
Hormone Receptor-Positive BreastGynecologicDesmoid+1 more
National Cancer Institute (NCI) 40
Early research (Phase 1)Study completedNCT02197884
What this trial is testing

Assess Effects of Clarithromycin on Pharmacokinetics of JNJ-54861911 in Healthy Male Participants

Who this might be right for
Healthy
Janssen Research & Development, LLC 13
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