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Results for “Cytochrome P-450”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT02286934
What this trial is testing

Cytochrome P450 2D6 Genotype on the Clinical Effect of Carvedilol

Who this might be right for
Healthy
Seoul National University Hospital 24
Early research (Phase 1)Study completedNCT03411122
What this trial is testing

Evaluate the Safety, Tolerability, Pharmacokinetics and Drug Interaction Potential of Napabucasin in Healthy Volunteers

Who this might be right for
Drug-drug Interactions
Sumitomo Pharma America, Inc. 30
Not applicableEnded earlyNCT00981929
What this trial is testing

Development of Cocktail for Measuring the Activity of Important Cytochrome P450 Enzymes

Who this might be right for
Cytochrome P450 Phenotype and Genotype Metrics
University of Southern Denmark 412
Early research (Phase 1)Study completedNCT01289756
What this trial is testing

Influence of Pharmacogenetic Factors, Paroxetine and Clarithromycin on Pharmacokinetics of Clomiphene

Who this might be right for
AnovulationDisorder Due Cytochrome P450 CYP2D6 VariantCytochrome P450 CYP3A Enzyme Deficiency
Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF) 20
Not applicableNot Yet RecruitingNCT07750587
What this trial is testing

Predicting Response and Exposure Changes in Cirrhosis for Effectiveness

Who this might be right for
Liver Cirrhosis
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 45
Not applicableStudy completedNCT01082796
What this trial is testing

Cytochrome P450 2C19 Variant is Related to Pharmacokinetics of Glipizide Extended Release Tablet in Chinese Subjects

Who this might be right for
GenotypePharmacokinetic
Chinese Academy of Sciences 14
Early research (Phase 1)Study completedNCT01929603
What this trial is testing

Study to Assess the Effect of Rifampicin (CYP Inducer) on Blood Levels and Safety of Olaparib in Patients With Advanced Solid Tumours

Who this might be right for
Solid Tumours
AstraZeneca 32
Not applicableStudy completedNCT01847729
What this trial is testing

OPAL: "Opiates and PhArmacoLogy"

Who this might be right for
Substance Use Disorder
Nantes University Hospital 263
Very early researchLooking for participantsNCT06693960
What this trial is testing

Evaluating the Pharmacokinetics of Oregano and Potential Oregano-drug Interactions Using a Drug Cocktail Approach

Who this might be right for
Interaction
Washington State University 16
Early research (Phase 1)Study completedNCT03222310
What this trial is testing

Evaluate the Effect of a Potent Cytochrome P450 (CYP) 3A Inhibitor on Ipatasertib

Who this might be right for
Healthy Volunteers
Hoffmann-La Roche 15
Early research (Phase 1)Study completedNCT02688088
What this trial is testing

Abemaciclib in Participants With Cancer That is Advanced or Has Spread to Another Part(s) of the Body

Who this might be right for
Neoplasm Metastasis
Eli Lilly and Company 48
Early research (Phase 1)Study completedNCT05304533
What this trial is testing

Assess the Drug Interaction Between MYK-224 and Itraconazole and Verapamil in Healthy Participants

Who this might be right for
Healthy Participants
Bristol-Myers Squibb 45
Early research (Phase 1)Study completedNCT01784536
What this trial is testing

Open Label Study Evaluating the Effects of a Single Oritavancin Infusion on Cytochrome P450 in Healthy Volunteers

Who this might be right for
Healthy
Melinta Therapeutics, Inc. 16
Early research (Phase 1)Study completedNCT00984009
What this trial is testing

A Drug-Food Interaction Study Between Colchicine and Grapefruit Juice

Who this might be right for
Pharmacokinetics
Mutual Pharmaceutical Company, Inc. 24
Early research (Phase 1)Study completedNCT03058419
What this trial is testing

Evaluate the Effect of Oral Doses of JNJ-54175446 on the Inhibition of Cytochrome P450 CYP3A4, CYP2C9, CYP1A2 and CYP2D6 Activity and the Induction of CYP2B6 and CYP2C19 Activity Using a Multiple Probe Substrate Cocktail in Healthy Subjects

Who this might be right for
Healthy
Janssen Research & Development, LLC 16
Early research (Phase 1)Study completedNCT05084651
What this trial is testing

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Itraconazole

Who this might be right for
Malaria
Novartis Pharmaceuticals 19
Early research (Phase 1)Study completedNCT05395117
What this trial is testing

Assess the Effect of AZD5462 on the Pharmacokinetics of Midazolam, Rosuvastatin and Digoxin

Who this might be right for
Healthy Participants
AstraZeneca 32
Early research (Phase 1)Study completedNCT00983216
What this trial is testing

Drug-Drug Interaction Study Between Colchicine and Ketoconazole

Who this might be right for
Pharmacokinetics
Mutual Pharmaceutical Company, Inc. 24
Early research (Phase 1)Study completedNCT06547164
What this trial is testing

Investigate the Pharmacokinetics of Midazolam After Repeated Doses of Camizestrant (AZD9833) and to Investigate the Pharmacokinetics of Camizestrant When Administered Alone and in Combination With Carbamazepine in Healthy Post-Menopausal Female Participants

Who this might be right for
Healthy Participants
AstraZeneca 40
Early research (Phase 1)Study completedNCT04713254
What this trial is testing

Drug Drug Interaction Study With Lu AG06466 in Young Healthy Men

Who this might be right for
Healthy
H. Lundbeck A/S 15
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