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Results for “Cytochrome P450 Enzyme Deficiency”

21 trials

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Showing 20 of 21 results

Early research (Phase 1)Study completedNCT00362726
What this trial is testing

Drug Interaction Study With Atazanavir Administered With and Without Ritonavir and a Cytochrome P450 Substrate Rosiglitazone

Who this might be right for
HIV Infections
Bristol-Myers Squibb 14
Not applicableEnded earlyNCT00207948
What this trial is testing

Optimizing Antiretroviral Therapy in HIV-Infected Children and Adolescents

Who this might be right for
HIV Infections
Children's National Research Institute 4
Not applicableUnknownNCT04389424
What this trial is testing

Relationship Between Body Composition, Food Consumption, and Micro and Macronutrients With Gene Expression in Breast Cancer

Who this might be right for
Breast CancerEndocrine TherapyEndocrine Therapy Adverse Reaction+3 more
Instituto Jalisciense de Cancerologia 300
Not applicableEnded earlyNCT03052218
What this trial is testing

Evaluation of Pupillometry for cyp2d6 Phenotyping in Children Treated With Tramadol

Who this might be right for
Drug IntoleranceCytochrome P450 CYP2D6 Enzyme DeficiencyDrug Effect
University Hospital, Geneva 50
Early research (Phase 1)Study completedNCT01289756
What this trial is testing

Influence of Pharmacogenetic Factors, Paroxetine and Clarithromycin on Pharmacokinetics of Clomiphene

Who this might be right for
AnovulationDisorder Due Cytochrome P450 CYP2D6 VariantCytochrome P450 CYP3A Enzyme Deficiency
Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF) 20
Post-approval studies (Phase 4)Study completedNCT00245986
What this trial is testing

Effect of Genetics on Metabolism of Efavirenz

Who this might be right for
Metabolism
National Institutes of Health Clinical Center (CC) 350
Early research (Phase 1)Study completedNCT00002194
What this trial is testing

An Open-Label Study in HIV+ Patients to Determine the Effects of Nevirapine (Viramune) on the Pharmacokinetics of Clarithromycin and Activity of Cytochrome 3A4.

Who this might be right for
HIV Infections
Boehringer Ingelheim 36
Not applicableStudy completedNCT06756620
What this trial is testing

Investigation of the Etiology of Hypertension and Endothelial Damage in Patients With Cytochrome P450 Oxidoreductase Deficiency

Who this might be right for
Cytochrome P450 Oxidoreductase DeficiencyHypertensionEndothelial Dysfunction+1 more
Ozge Bayrak Demirel 51
Not applicableStudy completedNCT03015025
What this trial is testing

Pharmacogenetic Dosage Algorithm for Acenocoumarol

Who this might be right for
Atrial FibrillationVenous ThrombosesCardiac Valve Disease
Instituto de Investigación Hospital Universitario La Paz 340
Not applicableStudy completedNCT02191358
What this trial is testing

YouScript IMPACT Registry

Who this might be right for
Adverse Drug EventsAdverse Drug ReactionsDrug Interaction Potentiation+10 more
Genelex Corporation 800
Early research (Phase 1)Study completedNCT05631704
What this trial is testing

Investigate Safety, Tolerability, and Pharmacokinetics (PK) of VH4524184 and the Potential for Changes in Cytochrome P450 3A (CYP3A) Activity

Who this might be right for
HIV Infections
ViiV Healthcare 84
Not applicableStudy completedNCT02378220
What this trial is testing

Pharmacogenetic Testing Among Home Health Patients

Who this might be right for
Adverse Drug EventsAdverse Drug ReactionsDrug Interaction Potentiation+10 more
Genelex Corporation 110
Post-approval studies (Phase 4)Study completedNCT03204578
What this trial is testing

Physiological Study of the Human CYP3A Activity (PiSA)

Who this might be right for
Cytochrome P450 CYP3A Enzyme Deficiency
University Hospital, Basel, Switzerland 12
Not applicableStudy completedNCT02428660
What this trial is testing

Drug & Gene Interaction Risk Analysis With & Without Genetic Testing Among Patients Undergoing MTM

Who this might be right for
Cytochrome P450 CYP2D6 Enzyme DeficiencyPoor Metabolizer Due to Cytochrome P450 CYP2D6 VariantUltrarapid Metabolizer Due to Cytochrome P450 CYP2D6 Variant+6 more
Genelex Corporation 341
Post-approval studies (Phase 4)Study completedNCT00050180
What this trial is testing

Influence of the MDR1 Genotype on Blood Levels of Indinavir and Saquinavir in Healthy Volunteers

Who this might be right for
HealthyHIV Infections
National Institutes of Health Clinical Center (CC) 81
Early research (Phase 1)Study completedNCT02819102
What this trial is testing

An Open-label Drug-Drug Interaction Study to Evaluate the Effect of BCX7353 on Cytochrome P450 Enzyme Activity Using Probe Substrates

Who this might be right for
Hereditary Angioedema
BioCryst Pharmaceuticals 20
Post-approval studies (Phase 4)Study completedNCT02450487
What this trial is testing

Influence of Genotype of CYP2C9 on Clinical Efficacy and Pharmacokinetics of Piroxicam After Lower Third Molar Surgery

Who this might be right for
PainOther Surgical ProceduresImpacted Third Molar Tooth+1 more
University of Sao Paulo 105
Early research (Phase 1)Ended earlyNCT05458102
What this trial is testing

Drug-Drug Interaction Study of Vesatolimod in Adults With HIV-1 Who Have Very Low or Undetectable Virus Levels

Who this might be right for
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Gilead Sciences 18
Post-approval studies (Phase 4)Study completedNCT00054743
What this trial is testing

Differences in Blood Levels of Nevirapine in HIV-infected Patients in Uganda and the United States

Who this might be right for
HIV Infection
National Institutes of Health Clinical Center (CC) 24
Not applicableStudy completedNCT01944436
What this trial is testing

A Genetic and Perfusion Study of Response to Cognitive Enhancers in Lewy Body Disease

Who this might be right for
Lewy Body Disease
Sunnybrook Health Sciences Centre 57
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