Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “DDR Gene Mutation”

6 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 6 of 6 results

Early research (Phase 1)Not Yet RecruitingNCT06614751
What this trial is testing

A PARG Inhibitor DAT-2645 Monotherapy in Patients with Advanced/Metastatic Solid Tumors Harboring BRCA1/2 Loss of Function Alterations And/or Other Defects in the DDR Pathway

Who this might be right for
Solid CancersBRCA MutationHRD Cancer+8 more
Danatlas Pharmaceuticals Co., Ltd 112
Large-scale testing (Phase 3)Active Not RecruitingNCT04821622
What this trial is testing

Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC

Who this might be right for
Prostate Cancer
Pfizer 599
Testing effectiveness (Phase 2)Ended earlyNCT04030559
What this trial is testing

Niraparib Before Surgery in Treating Patients With High Risk Localized Prostate Cancer and DNA Damage Response Defects

Who this might be right for
ATM Gene MutationBRCA1 Gene MutationBRCA2 Gene Mutation+14 more
University of California, Davis 11
Testing effectiveness (Phase 2)Looking for participantsNCT05222971
What this trial is testing

Olaparib With or Without Durvalumab for DDR Gene Mutated Biliary Tract Cancer Following Platinum-based Chemotherapy

Who this might be right for
Biliary Tract CancerDNA Damage Repair Deficiency
Asan Medical Center 62
Testing effectiveness (Phase 2)UnknownNCT04761744
What this trial is testing

A Phase II Study of Nivolumab in Patients With Genetic Alterations in DNA Damage Repair and Response Who Progressed After Standard Treatment for Metastatic Solid Cancers

Who this might be right for
DDR Gene MutationMetastatic Solid Tumor
Korean Cancer Study Group 48
Testing effectiveness (Phase 2)Active Not RecruitingNCT05933265
What this trial is testing

Study of LP-184 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorGBM+4 more
Lantern Pharma Inc. 64