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Results for “DLL3-expressing Tumors”

13 trials

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Showing 13 of 13 results

Not applicableLooking for participantsNCT07458906
What this trial is testing

DLL3-Targeted PET/CT in Neuroendocrine Carcinoma

Who this might be right for
DLL3-expressing TumorsPET / CTNeuroendocrine Cancer
The First Affiliated Hospital of Xiamen University 80
Early research (Phase 1)Looking for participantsNCT05916313
What this trial is testing

Test How Well Different Doses of BI 764532 Are Tolerated by People With a Tumour in the Brain That is Positive for DLL3

Who this might be right for
Glioma
Boehringer Ingelheim 20
Testing effectiveness (Phase 2)Looking for participantsNCT06814496
What this trial is testing

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

Who this might be right for
MelanomaMedullary Thyroid CancerSinonasal Undifferentiated Carcinoma+8 more
University of Arizona 30
Large-scale testing (Phase 3)WithdrawnNCT03334487
What this trial is testing

Study Evaluating the Safety of Rovalpituzumab Tesirine for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Small Cell Lung Cancer

Who this might be right for
Small Cell Lung Cancer
AbbVie
Testing effectiveness (Phase 2)Active Not RecruitingNCT06788938
What this trial is testing

Tarlatamab in Advanced Delta-like 3 (DLL3)-Expressing Tumors Including Neuroendocrine Neoplasms

Who this might be right for
DLL3-expressing TumorsAdvanced Tumors
Jonsson Comprehensive Cancer Center 29
Testing effectiveness (Phase 2)Looking for participantsNCT07174583
What this trial is testing

IDE849 in Patients With DLL3 Expressing Tumors Including Small Cell Lung Cancer

Who this might be right for
Small-cell Lung CancerNeuroendocrine CarcinomasSolid Tumor Show to Express DLL3
IDEAYA Biosciences 262
Testing effectiveness (Phase 2)Ended earlyNCT02709889
What this trial is testing

Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors

Who this might be right for
Malignant MelanomaMedullary Thyroid CancerGlioblastoma+5 more
AbbVie 200
Testing effectiveness (Phase 2)Looking for participantsNCT05652686
What this trial is testing

Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)

Who this might be right for
Small Cell Lung Cancer (SCLC)Large Cell Neuroendocrine Cancer (LCNEC)Neuroendocrine Prostate Cancer (NEPC)+3 more
Phanes Therapeutics 203
Testing effectiveness (Phase 2)Looking for participantsNCT07278479
What this trial is testing

Study of [212Pb]Pb-DOTAM-MAM279 ([212Pb]Pb-MP0712) in Patients With Small Cell Lung Cancer and Other DLL3 Expressing Solid Tumors

Who this might be right for
Large Cell Neuroendocrine CarcinomaLarge Cell Pulmonary Neuroendocrine Carcinoma of the Lung (LCNEC)Extrapulmonary Neuroendocrine Carcinoma (EP-NEC)+4 more
Molecular Partners AG 138
Early research (Phase 1)Looking for participantsNCT07006727
What this trial is testing

Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors

Who this might be right for
Small Cell Lung CarcinomaLarge Cell Neuroendocrine Carcinoma of the LungNeuroendocrine Prostate Cancer+8 more
Novartis Pharmaceuticals 116
Testing effectiveness (Phase 2)Study completedNCT02674568
What this trial is testing

Study of Rovalpituzumab Tesirine (SC16LD6.5) for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Delta-Like Protein 3-Expressing Small Cell Lung Cancer

Who this might be right for
Small Cell Lung Cancer
AbbVie 342
Early research (Phase 1)Active Not RecruitingNCT04429087
What this trial is testing

Test Different Doses of Obrixtamig in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3

Who this might be right for
Small Cell Lung Carcinoma and Other Neuroendocrine Neoplasms Expressing DLL3
Boehringer Ingelheim 306
Early research (Phase 1)Active Not RecruitingNCT05879978
What this trial is testing

Test How Well Different Doses of Obrixtamig (BI 764532) in Combination With Ezabenlimab Are Tolerated by People With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3

Who this might be right for
Small Cell Lung Carcinoma (SCLC)Neuroendocrine Neoplasms
Boehringer Ingelheim 45