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Results for “DMMR Cancer”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)UnknownNCT04152889
What this trial is testing

Evaluate Camrelizumab in Combination With Docetaxel +S-1 as Adjuvant Treatment Therapy in Stage III Gastric Cancer

Who this might be right for
Gastric Cancer Stage III
RenJi Hospital 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07595523
What this trial is testing

Iparomlimab Tolvorlimab as Neoadjuvant Immunotherapy for Locally Advanced Gastric Adenocarcinoma With Microsatellite Instability/Mismatch Repair Deficiency

Who this might be right for
Gastric Cancer
Peking University Cancer Hospital & Institute 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT04729322
What this trial is testing

Fecal Microbiota Transplant and Re-introduction of Anti-PD-1 Therapy (Pembrolizumab or Nivolumab) for the Treatment of Metastatic Colorectal Cancer in Anti-PD-1 Non-responders

Who this might be right for
Metastatic Colorectal AdenocarcinomaMetastatic Small Intestinal AdenocarcinomaStage IV Colorectal Cancer AJCC v8+4 more
M.D. Anderson Cancer Center 15
Testing effectiveness (Phase 2)Looking for participantsNCT04114136
What this trial is testing

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

Who this might be right for
MelanomaNSCLCHepatocellular Carcinoma+5 more
Dan Zandberg 72
Testing effectiveness (Phase 2)Study completedNCT06428487
What this trial is testing

Neoadjuvant Prolgolimab Monotherapy in Locally Advanced MMR-deficient Colorectal Cancer

Who this might be right for
Colorectal Cancer
Blokhin's Russian Cancer Research Center 30
Not applicableUnknownNCT03757247
What this trial is testing

Prevalence of Constitutional Mismatch-repair Deficiency Among Suspected Neurofibromatosis Type 1/Legius Syndrome Children Without a Malignancy and Without a NF1 or SPRED1 Mutation

Who this might be right for
Neurofibromatosis Type 1
Medical University Innsbruck 670
Testing effectiveness (Phase 2)Active Not RecruitingNCT03607890
What this trial is testing

Study of Nivolumab and Relatlimab in Advanced Mismatch Repair Deficient Cancers Resistant to Prior PD-(L)1 Inhibitor

Who this might be right for
Refractory MSI - H Solid Tumors Prior of PD-(L) 1 TherapyMSI-H Tumors
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 38
Not applicableLooking for participantsNCT03452774
What this trial is testing

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

Who this might be right for
Cancer, MetastaticCancerCancer of Pancreas+40 more
Massive Bio, Inc. 50,000
Early research (Phase 1)Study completedNCT03894618
What this trial is testing

SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas

Who this might be right for
Squamous Cell Carcinoma of the Head and NeckMelanomaNon Small Cell Lung Cancer+10 more
Shattuck Labs, Inc. 49
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07403877
What this trial is testing

Neoadjuvant Immunotherapy ± Radiotherapy in MSI-H/dMMR Locally Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer (MSI-H)
Fudan University 114
Large-scale testing (Phase 3)Looking for participantsNCT05770102
What this trial is testing

DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition

Who this might be right for
MalignancyMalignant NeoplasmLymphoproliferative Disorders+7 more
Cancer Research UK 30
Testing effectiveness (Phase 2)Study completedNCT04019964
What this trial is testing

Nivolumab in Biochemically Recurrent dMMR Prostate Cancer

Who this might be right for
Prostate CancerRecurrent Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 8
Testing effectiveness (Phase 2)UnknownNCT05371197
What this trial is testing

Envafolimab as Neoadjuvant Immuntherapy in Resectable Local Advanced dMMR/MSI-H Colorectal Cancer

Who this might be right for
Colorectal CancerMismatch Repair-deficient (dMMR)Microsatellite Instability-high (MSI-H)+1 more
Third Affiliated Hospital, Sun Yat-Sen University 26
Not applicableLooking for participantsNCT05129605
What this trial is testing

Prostate Cancer Genetic Risk Evaluation and Screening Study

Who this might be right for
Prostatic NeoplasmProstate CancerBRCA2 Mutation+5 more
Massachusetts General Hospital 400
Testing effectiveness (Phase 2)UnknownNCT05994456
What this trial is testing

Neoadjuvant Toripalimab for dMMR/MSI-H Gastric Cancer

Who this might be right for
Gastric or Gastroesophageal Junction Adenocarcinoma
Sun Yat-sen University 24
Testing effectiveness (Phase 2)Ended earlyNCT03050814
What this trial is testing

Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004

Who this might be right for
Colorectal TumorsColorectal NeoplasmsColorectal Carcinoma+2 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT04751370
What this trial is testing

Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal AdenocarcinomaStage II Rectal Cancer AJCC v8Stage III Rectal Cancer AJCC v8
National Cancer Institute (NCI) 31
Testing effectiveness (Phase 2)Looking for participantsNCT04774419
What this trial is testing

Radiation and TSR-042 (Dostarlimab) in People With Endometrial Cancer After They Receive Surgery

Who this might be right for
Endometrial Cancer
Memorial Sloan Kettering Cancer Center 62
Testing effectiveness (Phase 2)Looking for participantsNCT06698757
What this trial is testing

Different Cycles of Preoperative Neoadjuvant Sintilimab in Mismatch-repair Deficient/microsatellite Instability-high, Locally Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Yugui Lian 96
Early research (Phase 1)Study completedNCT02635672
What this trial is testing

Phase I Dose Escalation Study for VIP152 in Patients With Advanced Cancer

Who this might be right for
Neoplasms
Vincerx Pharma, Inc. 110
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