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Results for “DMMR Solid Malignant Tumor”

50 trials

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Showing 20 of 50 results

Testing effectiveness (Phase 2)Looking for participantsNCT03667170
What this trial is testing

KN035 for dMMR/MSI-H Advanced Solid Tumors

Who this might be right for
Solid Tumor
3D Medicines (Sichuan) Co., Ltd. 200
Large-scale testing (Phase 3)Looking for participantsNCT06279130
What this trial is testing

Pan-tumor Neoadjuvant Basket Study of Immune Check-point Inhibition and Novel Immuno-oncology Combinations

Who this might be right for
Resectable MMR-deficient Solid TumorsResectable MMR-proficient Solid Tumors
The Netherlands Cancer Institute 133
Early research (Phase 1)Study completedNCT04242199
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorMSI-H/dMMR TumorsCutaneous Squamous Cell Carcinoma+9 more
Incyte Corporation 182
Testing effectiveness (Phase 2)Active Not RecruitingNCT03935893
What this trial is testing

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

Who this might be right for
Gastric CancerColorectal CancerPancreatic Cancer+7 more
Udai Kammula 20
Testing effectiveness (Phase 2)WithdrawnNCT04001101
What this trial is testing

Anti-PD-1 +/- RT for MSI-H Solid Tumors

Who this might be right for
Microsatellite Instability HighMismatch Repair DeficiencyColorectal Cancer
University of Colorado, Denver
Testing effectiveness (Phase 2)Looking for participantsNCT04114136
What this trial is testing

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

Who this might be right for
MelanomaNSCLCHepatocellular Carcinoma+5 more
Dan Zandberg 72
Testing effectiveness (Phase 2)Active Not RecruitingNCT05879822
What this trial is testing

Evaluate INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor Naive

Who this might be right for
Advanced Solid Tumor
Incyte Corporation 73
Testing effectiveness (Phase 2)WithdrawnNCT06400264
What this trial is testing

Testing Nivolumab and BMS-986016 (Relatlimab) as Potentially Targeting Treatment in Cancers That Are LAG-3+ and Have Mismatch Repair Deficiency (MATCH - Subprotocol Z1M)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmRefractory Lymphoma+2 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Looking for participantsNCT06362369
What this trial is testing

Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

Who this might be right for
Advanced CancerAdvanced Solid TumorMelanoma+15 more
7 Hills Pharma, LLC 126
Testing effectiveness (Phase 2)UnknownNCT03475953
What this trial is testing

A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors

Who this might be right for
Colorectal Cancer Not MSI-H or MMR-deficientGISTOesophageal or Gastric Carcinoma+12 more
Institut Bergonié 747
Early research (Phase 1)Ended earlyNCT04272034
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsMSI-H/dMMR TumorsCutaneous Squamous Cell Carcinoma+15 more
Incyte Corporation 105
Not applicableUnknownNCT06004713
What this trial is testing

Registry Study in MSI/dMMR Solid Tumors

Who this might be right for
DMMR CancerMSI-HSolid Tumor
Peking University Cancer Hospital & Institute 190
Early research (Phase 1)Looking for participantsNCT06004245
What this trial is testing

Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsColorectal Cancer
Vividion Therapeutics, Inc. 280
Early research (Phase 1)Ended earlyNCT04458259
What this trial is testing

Study of PF-07265807 in Participants With Metastatic Solid Tumors.

Who this might be right for
Neoplasm Metastasis
Pfizer 88
Early research (Phase 1)Looking for participantsNCT06974110
What this trial is testing

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorEndometrial Cancer+4 more
MOMA Therapeutics 132
Testing effectiveness (Phase 2)Looking for participantsNCT06898450
What this trial is testing

Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

Who this might be right for
Advanced Solid Tumors CancerMSI-H Cancer
Nimbus Wadjet, Inc. 134
Testing effectiveness (Phase 2)Active Not RecruitingNCT05199272
What this trial is testing

A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies

Who this might be right for
Solid TumorClear Cell Renal Cell CarcinomaEpithelial Ovarian Cancer+6 more
23andMe, Inc. 141
Early research (Phase 1)Study completedNCT03236935
What this trial is testing

Phase Ib of L-NMMA and Pembrolizumab

Who this might be right for
Non-Small Cell Lung CancerMalignant MelanomaHead and Neck Squamous Cell Carcinoma+3 more
The Methodist Hospital Research Institute 12
Testing effectiveness (Phase 2)Looking for participantsNCT03941574
What this trial is testing

A Clinical Study to Evaluate HLX10 Monotherapy for the Treatment of MSI-H or dMMR Solid Tumors That Failed to Respond to Standard Therapy

Who this might be right for
MSI-H Solid Malignant Tumor
Shanghai Henlius Biotech 108
Testing effectiveness (Phase 2)Looking for participantsNCT06580574
What this trial is testing

Immune Checkpoint Inhibitors for Organ Preservation in Non-metastatic dMMR/MSI-H Gastric or Colon Cancers

Who this might be right for
Gastric CancerColon CancerMSI-H+1 more
Peking University 34
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