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Results for “DNA Damage”

169 trials

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Showing 20 of 169 results

Not applicableStudy completedNCT00416390
What this trial is testing

Lycopene in Treating Patients With Prostate Cancer or Benign Prostatic Hyperplasia

Who this might be right for
Nonmalignant NeoplasmProstate Cancer
University of Illinois at Chicago 120
Testing effectiveness (Phase 2)Looking for participantsNCT03609216
What this trial is testing

Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations

Who this might be right for
Infiltrating Bladder Urothelial CarcinomaStage II Bladder Urothelial CarcinomaStage III Bladder Urothelial Carcinoma
Alliance for Clinical Trials in Oncology 271
Early research (Phase 1)Study completedNCT03030417
What this trial is testing

Indenoisoquinoline LMP744 in Adults With Relapsed Solid Tumors and Lymphomas

Who this might be right for
Solid TumorsLymphoma
National Cancer Institute (NCI) 36
Testing effectiveness (Phase 2)Study completedNCT01851369
What this trial is testing

TRC102 and Temozolomide for Relapsed Solid Tumors and Lymphomas

Who this might be right for
LymphomasSolid TumorsNSCLC+2 more
National Cancer Institute (NCI) 93
Testing effectiveness (Phase 2)Study completedNCT04939662
What this trial is testing

Olaparib and Bevacizumab in Relapsed Small Cell Lung Cancer Subjects

Who this might be right for
Lung Cancer
Se-Hoon Lee 25
Large-scale testing (Phase 3)Active Not RecruitingNCT04821622
What this trial is testing

Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC

Who this might be right for
Prostate Cancer
Pfizer 599
Not applicableLooking for participantsNCT06323603
What this trial is testing

Biomonitoring of Occupationally Populations Exposed to Micro and Nanoplastic

Who this might be right for
Occupational ExposureGenotoxicityDamage Dna
Ricard Marcos 45
Not applicableUnknownNCT03652142
What this trial is testing

Predictive Biomarkers for Response to Nivolumab in Head and Neck Squamous Cell Carcinoma

Who this might be right for
HNSCCDNA DamageDNA Double Strand Break
Attikon Hospital 50
Early research (Phase 1)Active Not RecruitingNCT05396833
What this trial is testing

Study of Tuvusertib (M1774) in Combination With DNA Damage Response Inhibitor or Immune Checkpoint Inhibitor (DDRiver Solid Tumors 320)

Who this might be right for
Metastatic or Locally Advanced Unresectable Solid Tumors
EMD Serono Research & Development Institute, Inc. 120
Testing effectiveness (Phase 2)Active Not RecruitingNCT03851614
What this trial is testing

Study of DNA Damage, Angiogenesis, and PD-L1 Inhibitors in Advanced Solid Tumors

Who this might be right for
Mismatch Repair Proficient Colorectal CancerPancreatic AdenocarcinomaLeiomyosarcoma
University Health Network, Toronto 90
Not applicableStudy completedNCT07279896
What this trial is testing

Determination of RNA/DNA Damage Associated With Oxidative Stress in Periodontitis Patients

Who this might be right for
Periodontitis (Stage 3)Smoking
Zehra Hasgül 88
Not applicableStudy completedNCT01293591
What this trial is testing

Garlic Intake And Biomarkers Of Cancer Risk

Who this might be right for
Healthy MenHealthy Women
USDA Beltsville Human Nutrition Research Center 18
Early research (Phase 1)Study completedNCT04095273
What this trial is testing

Study to Test How Well Patients With Advanced Solid Tumors Respond to Treatment With the Elimusertib in Combination With Pembrolizumab, to Find the Optimal Dose for Patients, How the Drug is Tolerated and the Way the Body Absorbs, Distributes and Discharges the Drug

Who this might be right for
Advanced Solid Tumors
Bayer 56
Testing effectiveness (Phase 2)Ended earlyNCT03782818
What this trial is testing

Olaparib for PAH: a Multicenter Clinical Trial

Who this might be right for
Pulmonary Arterial Hypertension
Laval University 17
Testing effectiveness (Phase 2)Study completedNCT04564027
What this trial is testing

A Study Investigating DNA-damage Response Agents in Molecularly Altered Advanced Cancer

Who this might be right for
Advanced Solid Tumours
AstraZeneca 54
Not applicableStudy completedNCT05573789
What this trial is testing

Tumor Molecular Profiling in Patients With Prostate Cancer

Who this might be right for
Prostate CancerMetastatic Prostate Adenocarcinoma
Hellenic Cooperative Oncology Group 220
Early research (Phase 1)WithdrawnNCT06719973
What this trial is testing

Phase 1 Study of M9466 Combined With Carboplatin and Platinum-based Anticancer Therapy (DDRiver 521)

Who this might be right for
Advanced Solid Tumors
EMD Serono Research & Development Institute, Inc.
Not applicableUnknownNCT05277961
What this trial is testing

Quantification of DNA Repair Products in the Urine After Ultraviolet Radiation of the Skin

Who this might be right for
Ultraviolet Rays; InjuryDNA Adduct FormationDNA Damage, Radiation Induced+1 more
Bispebjerg Hospital 80
Early research (Phase 1)Looking for participantsNCT05687110
What this trial is testing

Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

Who this might be right for
Metastatic Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
National Cancer Institute (NCI) 43
Testing effectiveness (Phase 2)Looking for participantsNCT04711824
What this trial is testing

Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases

Who this might be right for
Breast CancerBrain Metastases, Adult
Colette Shen 41
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