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Results for “DNA Damage”

171 trials

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Showing 20 of 171 results

Not applicableStudy completedNCT05007171
What this trial is testing

Changes in Anthropometric, Biochemical and DNA Damage Parameters After 3-weeks VLCD in Severely Obese Patients

Who this might be right for
ObesityWeight LossDNA Damage
Special Hospital for Extended Treatment of Duga Resa 22
Not applicableStudy completedNCT02310087
What this trial is testing

Oral Astaxanthin and Semen Quality, Fertilization and Embryo Development in Assisted Reproduction Techniques Procedures

Who this might be right for
Infertility, Male
University Medical Centre Ljubljana 80
Early research (Phase 1)Looking for participantsNCT06487481
What this trial is testing

Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical Carcinoma

Who this might be right for
Adrenocortical Carcinoma (ACC)Recurrent Adrenocortical Carcinoma (ACC)Recurrent Abdominal Adrenocortical Carcinoma (ACC)+2 more
National Cancer Institute (NCI) 32
Not applicableStudy completedNCT07301515
What this trial is testing

Randomised Controlled Trial of an Antioxidant and Sunscreen Combination Cream for Reducing DNA Damage in Human Skin

Who this might be right for
PhotoagingPhotodamageMitochondrial Damage+3 more
Klira Skin 52
Testing effectiveness (Phase 2)Study completedNCT03207347
What this trial is testing

A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001)

Who this might be right for
MesotheliomaUveal MelanomaRenal Cell Carcinoma+1 more
University of Florida 37
Testing effectiveness (Phase 2)Looking for participantsNCT04550494
What this trial is testing

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Castration-Resistant Prostate Carcinoma+28 more
National Cancer Institute (NCI) 36
Post-approval studies (Phase 4)Study completedNCT00854178
What this trial is testing

Toxicogenomic and Immunocytotoxic Effects of Propofol and Isoflurane Anesthetics in Patients Undergoing Elective Surgery

Who this might be right for
Patients in Good HealthTypes of General AnesthesiaDNA Damage
UPECLIN HC FM Botucatu Unesp 26
Not applicableUnknownNCT04453267
What this trial is testing

DNA Repair in Patients With Stable Angina.

Who this might be right for
Coronary Artery DiseaseCoronary ArteriosclerosisDNA Damage+1 more
University Hospital Southampton NHS Foundation Trust 172
Not applicableStudy completedNCT03284632
What this trial is testing

E-Cigarette - DNA Adducts

Who this might be right for
SmokingCigarette SmokingElectronic Cigarettes
University of Minnesota 217
Not applicableStudy completedNCT07279896
What this trial is testing

Determination of RNA/DNA Damage Associated With Oxidative Stress in Periodontitis Patients

Who this might be right for
Periodontitis (Stage 3)Smoking
Zehra Hasgül 88
Testing effectiveness (Phase 2)Active Not RecruitingNCT05203445
What this trial is testing

Olaparib and Pembrolizumab in People With Triple Negative Breast Cancer (TNBC) or Hormone Receptor-positive HER2-negative Breast Cancer

Who this might be right for
Breast Cancer
Memorial Sloan Kettering Cancer Center 23
Early research (Phase 1)Study completedNCT01445522
What this trial is testing

ABT-888 Plus Metronomic Cyclophosphamide to Treat Cancer

Who this might be right for
NeoplasmsLymphoma
National Cancer Institute (NCI) 35
Not applicableActive Not RecruitingNCT06620666
What this trial is testing

NEUROmuscular Training for Enhanced AGE Longevity

Who this might be right for
AgingPhysical ActivityTraining
University of Valencia 390
Early research (Phase 1)Study completedNCT02630199
What this trial is testing

Study of AZD6738, DNA Damage Repair/Novel Anti-cancer Agent, in Combination With Paclitaxel, in Refractory Cancer

Who this might be right for
Refractory Cancer
Samsung Medical Center 65
Not applicableStudy completedNCT03104387
What this trial is testing

Health Effects of Occupational Exposure to Combustion Particles - a Study on Volunteers Performing as Train Conductors

Who this might be right for
Cardiovascular FunctionGenotoxicity
University of Copenhagen 29
Testing effectiveness (Phase 2)Active Not RecruitingNCT03851614
What this trial is testing

Study of DNA Damage, Angiogenesis, and PD-L1 Inhibitors in Advanced Solid Tumors

Who this might be right for
Mismatch Repair Proficient Colorectal CancerPancreatic AdenocarcinomaLeiomyosarcoma
University Health Network, Toronto 90
Testing effectiveness (Phase 2)Active Not RecruitingNCT03609216
What this trial is testing

Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations

Who this might be right for
Infiltrating Bladder Urothelial CarcinomaStage II Bladder Urothelial CarcinomaStage III Bladder Urothelial Carcinoma
Alliance for Clinical Trials in Oncology 237
Not applicableStudy completedNCT01143519
What this trial is testing

Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage

Who this might be right for
HIV-1 SeropositiveInflammationCancer+1 more
National Institute of Environmental Health Sciences (NIEHS) 178
Early research (Phase 1)Study completedNCT03022409
What this trial is testing

Investigate Biomarker Effects of Pre-Surgical Treatment With DNA Damage Repair (DDR) Agents in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC).

Who this might be right for
Head and Neck Squamous Cell Carcinoma
AstraZeneca 21
Testing effectiveness (Phase 2)UnknownNCT05461261
What this trial is testing

The Efficacy and Safety of Docetaxel Combined With Platinum for Metastatic Hormone-sensitive Prostate Cancer

Who this might be right for
Hormone Sensitive Metastatic Prostate CancerDNA Damage Repair DeficiencyChemotherapy Effect+1 more
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 50
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