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Results for “DNA Mutations”

221 trials

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Showing 20 of 221 results

Not applicableEnded earlyNCT03786107
What this trial is testing

HER-Seq: A Blood-based Screening Study to Identify Patients With HER2 Mutations for Enrollment Into Clinical Research Studies of Neratinib

Who this might be right for
Hormone Receptor-Positive, HER2-Negative Metastatic Breast CancerMetastatic Cervical Cancer
Puma Biotechnology, Inc. 1,583
Not applicableLooking for participantsNCT02288676
What this trial is testing

DOvEEgene/WISE Genomics: Diagnosing Ovarian and Endometrial Cancer Early Using Genomics

Who this might be right for
Ovarian NeoplasmsEndometrial NeoplasmsEndometrial Cancer+6 more
McGill University 1,200
Not applicableStudy completedNCT04448158
What this trial is testing

Dynamics of Drug Resistance-associated Mutations in HIV-1 DNA Reverse Transcriptase Clearance During Effective Antiretroviral Therapy

Who this might be right for
HIV-1-infection
Association de Recherche en Virologie et Dermatologie 79
Testing effectiveness (Phase 2)Study completedNCT04165239
What this trial is testing

The KHENERGYZE Study

Who this might be right for
Mitochondrial DiseasesMitochondrial MyopathiesMitochondrial Encephalomyopathies+2 more
Khondrion BV 27
Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Testing effectiveness (Phase 2)Active Not RecruitingNCT03344965
What this trial is testing

Olaparib In Metastatic Breast Cancer

Who this might be right for
Metastatic Breast CancerInvasive Breast CancerSomatic Mutation Breast Cancer (BRCA1)+7 more
Beth Israel Deaconess Medical Center 114
Not applicableStudy completedNCT02827565
What this trial is testing

Technical Optimization of Detection of KRAS, BRAF and NRAS Mutations on Tumor DNA Circulating in Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Institut de Cancérologie de Lorraine 30
Not applicableStudy completedNCT03562819
What this trial is testing

Study to Evaluate Concordance of Detecting EGFR (Epidermal Growth Factor Receptor) Mutation by Circulating Tumour Free DNA Versus Tissues Biopsy in NSCLC (Non-small Cell Lung Cancer).

Who this might be right for
NSCLC (Non-small Cell Lung Cancer)
AstraZeneca 268
Not applicableUnknownNCT03294343
What this trial is testing

Risk-Reducing Surgeries for Hereditary Ovarian Cancer

Who this might be right for
Hereditary Breast and Ovarian Cancer SyndromeColorectal Neoplasms, Hereditary NonpolyposisOvariectomy+1 more
Lei Li 600
Not applicableStudy completedNCT02331914
What this trial is testing

GIST: Assessment of Tumor Mutations and TKI Plasma Exposure

Who this might be right for
Gastro-intestinal Stromal Tumor
University Medical Center Groningen 740
Early research (Phase 1)WithdrawnNCT04548843
What this trial is testing

A First in Human Study to Evaluate the Safety of Infusion of MNV-BM-PLC (Autologous CD34+ Cells Enriched With Placenta Derived Allogeneic Mitochondria) in Patients With Primary Mitochondrial Diseases Associated With Mitochondrial DNA Mutation or Deletion

Who this might be right for
Primary Mitochondrial Diseases
Minovia Therapeutics Ltd.
Testing effectiveness (Phase 2)UnknownNCT04775862
What this trial is testing

A Prospective Study Utilizing Circulating Cell Free DNA (cfDNA) Use in the Detection of RAS Mutations in Patients With Advanced Colorectal Cancer.

Who this might be right for
Colon Cancer
National Guard Health Affairs 60
Large-scale testing (Phase 3)Active Not RecruitingNCT02883049
What this trial is testing

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations

Who this might be right for
B Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia, BCR-ABL1-LikeCentral Nervous System Leukemia+1 more
National Cancer Institute (NCI) 5,949
Not applicableEnrolling By InvitationNCT00341874
What this trial is testing

Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan

Who this might be right for
Hearing Disorder
National Institute on Deafness and Other Communication Disorders (NIDCD) 24,000
Not applicableUnknownNCT03259009
What this trial is testing

RAS Mutations in ctDNA and Anti-EGFR reINTROduction in mCRC (RASINTRO)

Who this might be right for
Metastatic Colorectal Cancer
Association des Gastroentérologues Oncologues 73
Not applicableUnknownNCT00831948
What this trial is testing

Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.

Who this might be right for
Mitochondrial DiseasesDiagnosisDNA Mutations
Centre Hospitalier Universitaire de Nice 20
Not applicableStudy completedNCT01198743
What this trial is testing

Presence of Circulating Tumor DNA in Colorectal Cancer

Who this might be right for
Colorectal Neoplasms
Assistance Publique - Hôpitaux de Paris 261
Not applicableLooking for participantsNCT03830229
What this trial is testing

Long Term Follow-up of Mesothelioma Patients and Their Family Members With Germline Mutations in BAP1 and Other Genes

Who this might be right for
MesotheliomaFamilies
National Cancer Institute (NCI) 1,000
Not applicableStudy completedNCT02815137
What this trial is testing

Detection and Prognostic Value of Recurrent XPO1 Mutations of Patients With Classical Hodgkin Lymphoma

Who this might be right for
Classical Hodgkin Lymphoma
Centre Henri Becquerel 137
Testing effectiveness (Phase 2)UnknownNCT04042831
What this trial is testing

Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations

Who this might be right for
Bile Duct AdenocarcinomaFanconi Anemia Complementation Group Gene MutationMetastatic Bile Duct Carcinoma+1 more
Academic and Community Cancer Research United 36
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