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Results for “DNA Mutations”

227 trials

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Showing 20 of 227 results

Not applicableUnknownNCT05604573
What this trial is testing

DNA Mutation Detection in Circulating Tumor DNA and Tissue by mmADPS for Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Seoul National University Hospital 150
Not applicableLooking for participantsNCT05378204
What this trial is testing

Study Evaluating DNA Double-strand Breaks (DSBs) REpair Factors (POLQ, Shieldin Complex and 53BP1) Expression as Biomarker of PARP Inhibitor Resistance in Patients With Deleterious Germline Mutation in BRCA 1/2 and HER2-negative, Metastatic or Locally Advanced Breast Cancer.

Who this might be right for
Breast Cancer
Institut Claudius Regaud 120
Not applicableStudy completedNCT04560270
What this trial is testing

CIrculating Tumor DNA for Monitoring Response to First Line Chemotherapy in Unresectable PANcreatic Cancer

Who this might be right for
Pancreatic CancerCirculating Tumor DNAKRAS Mutation-Related Tumors
Poitiers University Hospital 69
Testing effectiveness (Phase 2)Study completedNCT01854294
What this trial is testing

GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS)

Who this might be right for
Amyotrophic Lateral Sclerosis
Genervon Biopharmaceuticals, LLC 12
Testing effectiveness (Phase 2)Study completedNCT04165239
What this trial is testing

The KHENERGYZE Study

Who this might be right for
Mitochondrial DiseasesMitochondrial MyopathiesMitochondrial Encephalomyopathies+2 more
Khondrion BV 27
Not applicableLooking for participantsNCT04367246
What this trial is testing

Li-Fraumeni Syndrome/TP53 Biobank

Who this might be right for
Li-Fraumeni SyndromeLi-Fraumeni-Like Syndrome
Abramson Cancer Center at Penn Medicine 300
Testing effectiveness (Phase 2)Study completedNCT04740190
What this trial is testing

Talazoparib - Carboplatin for Recurrent High-grade Glioma With DDRd

Who this might be right for
Recurrent GliomaRecurrent GlioblastomaPoly ADP Ribose Polymerase (PARP) Inhibitor+2 more
The University of Hong Kong 33
Not applicableStudy completedNCT00023049
What this trial is testing

Genetic Analysis of Hereditary Disorders of Hearing and Balance

Who this might be right for
Sensorineural Hearing LossHearing DisorderVestibular Disease
National Institute on Deafness and Other Communication Disorders (NIDCD) 335
Not applicableLooking for participantsNCT07556562
What this trial is testing

Early Diagnosis of High-grade Serous Epithelial Ovarian Cancer Through the Analysis of DNA Derived From Pap Test Smear.

Who this might be right for
Germline Mutations
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 260
Early research (Phase 1)Study completedNCT04991480
What this trial is testing

ART4215 for the Treatment of Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced CancerMetastatic CancerBreast Cancer
Artios Pharma Ltd 93
Testing effectiveness (Phase 2)UnknownNCT04761744
What this trial is testing

A Phase II Study of Nivolumab in Patients With Genetic Alterations in DNA Damage Repair and Response Who Progressed After Standard Treatment for Metastatic Solid Cancers

Who this might be right for
DDR Gene MutationMetastatic Solid Tumor
Korean Cancer Study Group 48
Not applicableUnknownNCT01902420
What this trial is testing

Aryl Hydrocarbon Receptor Interacting Protein (AIP) Gene Mutations in Acromegaly

Who this might be right for
Acromegaly
TC Erciyes University 80
Not applicableLooking for participantsNCT07498829
What this trial is testing

Population Based Germline Testing for Early Detection and Prevention of Cancer

Who this might be right for
Breast Cancer RiskOvarian Cancer RiskCancer Gene Mutation
Queen Mary University of London 6,000
Early research (Phase 1)Study completedNCT03318445
What this trial is testing

Rucaparib and Irinotecan in Cancers With Mutations in DNA Repair

Who this might be right for
Solid Tumor, Unspecified, Adult
Pamela Munster 22
Not applicableLooking for participantsNCT03280394
What this trial is testing

Liquid Biopsy in Mature B-cell Tumors

Who this might be right for
Mature B-Cell Neoplasm
Oncology Institute of Southern Switzerland 444
Not applicableLooking for participantsNCT03124212
What this trial is testing

Cascade Genetic Testing for Hereditary Breast/Ovarian Cancer and Lynch Syndrome in Switzerland

Who this might be right for
Hereditary Breast and Ovarian CancerLynch Syndrome
University of Basel 700
Testing effectiveness (Phase 2)Ended earlyNCT02706691
What this trial is testing

BGJ398 in Treating Patients With FGFR Positive Recurrent Head and Neck Cancer

Who this might be right for
FGFR Gene AmplificationFGFR1 Gene AmplificationFGFR2 Gene Amplification+7 more
University of Chicago 1
Not applicableWithdrawnNCT03087370
What this trial is testing

A Retrospective and Prospective Natural History Study of Patients With WHIM Syndrome

Who this might be right for
WHIM Syndrome
X4 Pharmaceuticals
Not applicableStudy completedNCT04087473
What this trial is testing

Plasma Molecular Profiling in ALK Inhibitor Resistant NSCLC

Who this might be right for
Non-small Cell Lung CancerALK-Positive Lung Cancer
National Cancer Centre, Singapore 50
Not applicableLooking for participantsNCT03702309
What this trial is testing

Liquid Biopsy Evaluation and Repository Development at Princess Margaret

Who this might be right for
CancerBreast CancerLung Cancer+15 more
University Health Network, Toronto 2,500
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