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Results for “DNA Mutations”

216 trials

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Showing 20 of 216 results

Testing effectiveness (Phase 2)Ended earlyNCT04171700
What this trial is testing

Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes

Who this might be right for
Solid Tumor
pharmaand GmbH 83
Not applicableStudy completedNCT00001885
What this trial is testing

Identification of Genes Associated With Lung Disease in Patients With Rheumatoid Arthritis

Who this might be right for
HealthyPulmonary FibrosisRheumatoid Arthritis
National Heart, Lung, and Blood Institute (NHLBI) 400
Testing effectiveness (Phase 2)Study completedNCT05229588
What this trial is testing

Lurbinectedin in Patients With Advanced Gastrointestinal Malignancies With DNA Repair Mutations

Who this might be right for
Gastrointestinal Malignancies
HonorHealth Research Institute 8
Not applicableActive Not RecruitingNCT02194387
What this trial is testing

Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members

Who this might be right for
Body Mass Index 25 or GreaterBRCA1 Gene MutationBRCA2 Gene Mutation+8 more
M.D. Anderson Cancer Center 337
Not applicableStudy completedNCT04314245
What this trial is testing

Diagnostic Evaluation of Urine DNA Methylation/Somatic Mutation Profiling for the Detection of Urothelial Carcinoma

Who this might be right for
Urothelial CarcinomaBladder Cancer
AnchorDx Medical Co., Ltd. 1,170
Not applicableUnknownNCT01902420
What this trial is testing

Aryl Hydrocarbon Receptor Interacting Protein (AIP) Gene Mutations in Acromegaly

Who this might be right for
Acromegaly
TC Erciyes University 80
Not applicableUnknownNCT02036216
What this trial is testing

Circulating Cell-free DNA as a Predictive Biomarker for Hepatocelluar Carcinoma.

Who this might be right for
Hepatocellular Carcinoma
Peking Union Medical College Hospital 200
Large-scale testing (Phase 3)Study completedNCT01462994
What this trial is testing

Detection of CF-DNA in Patients With Gastrointestinal Stromal Tumors (GIST)

Who this might be right for
Gastrointestinal Stromal Tumors
Technical University of Munich 25
Testing effectiveness (Phase 2)UnknownNCT02811354
What this trial is testing

Phase II Study of AZD9291 in Advanced Stage NSCLC With EGFR and T790M Mutations Detected in Plasma Ct-DNA

Who this might be right for
Carcinoma, Non-Small-Cell Lung
National University Hospital, Singapore 108
Not applicableLooking for participantsNCT03830229
What this trial is testing

Long Term Follow-up of Mesothelioma Patients and Their Family Members With Germline Mutations in BAP1 and Other Genes

Who this might be right for
MesotheliomaFamilies
National Cancer Institute (NCI) 1,000
Testing effectiveness (Phase 2)Study completedNCT04019327
What this trial is testing

The Drugs Talazoparib and Temozolomide in Prostate Cancer

Who this might be right for
Prostate CancerProstate AdenocarcinomaProstate Neoplasm+2 more
Memorial Sloan Kettering Cancer Center 16
Testing effectiveness (Phase 2)Study completedNCT01989546
What this trial is testing

Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA Mutations

Who this might be right for
Advanced Ovarian CancerPrimary Peritoneal CancerAdvanced Breast Cancer+1 more
National Cancer Institute (NCI) 9
Not applicableLooking for participantsNCT04095195
What this trial is testing

Registry of Subjects at Risk of Pancreatic Cancer

Who this might be right for
Familial Pancreatic CancerBRCA1 MutationBRCA2 Mutation+4 more
Associazione Italiana per lo Studio del Pancreas 1,000
Not applicableLooking for participantsNCT06779864
What this trial is testing

Molecular Characteristics of Hepatitis B Virus Integration, Mutation, and Drug Resistance

Who this might be right for
Chronic Hepatitis B
Beijing Friendship Hospital 2,000
Testing effectiveness (Phase 2)Active Not RecruitingNCT05625087
What this trial is testing

Detection of Tumor DNA in the Blood of Patients Receiving Standard Therapy for Hormone Receptor-positive (HR+) Non-HER2 Expressing (HER2-) Metastatic Breast Cancer as a Tool to Select Those Who May Benefit From the Next Course of Fulvestrant in Combination With Alpelisib or Ribociclib

Who this might be right for
Breast Cancer Stage IV
UNICANCER 162
Testing effectiveness (Phase 2)Looking for participantsNCT05933265
What this trial is testing

Study of LP-184 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorGBM+4 more
Lantern Pharma Inc. 175
Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Testing effectiveness (Phase 2)Active Not RecruitingNCT03344965
What this trial is testing

Olaparib In Metastatic Breast Cancer

Who this might be right for
Metastatic Breast CancerInvasive Breast CancerSomatic Mutation Breast Cancer (BRCA1)+7 more
Beth Israel Deaconess Medical Center 114
Testing effectiveness (Phase 2)Study completedNCT02909400
What this trial is testing

The KHENERGY Study

Who this might be right for
Mitochondrial DiseasesMitochondrial MyopathiesMitochondrial Encephalomyopathies+2 more
Khondrion BV 20
Not applicableStudy completedNCT02884063
What this trial is testing

Utilizing Free DNA in Embryo Culture for PGT

Who this might be right for
Chromosome AbnormalitiesGenetic Diseases, InbornMutation
Al Baraka Fertility Hospital 100
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