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Results for “DNA Repair Abnormality”

9 trials

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Showing 9 of 9 results

Testing effectiveness (Phase 2)Study completedNCT02952534
What this trial is testing

Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency

Who this might be right for
Metastatic Castration Resistant Prostate Cancer
pharmaand GmbH 277
Not applicableUnknownNCT04453267
What this trial is testing

DNA Repair in Patients With Stable Angina.

Who this might be right for
Coronary Artery DiseaseCoronary ArteriosclerosisDNA Damage+1 more
University Hospital Southampton NHS Foundation Trust 172
Large-scale testing (Phase 3)Active Not RecruitingNCT03522246
What this trial is testing

A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy

Who this might be right for
Epithelial Ovarian CancerPrimary PeritonealFallopian Tube Cancer+4 more
pharmaand GmbH 1,097
Large-scale testing (Phase 3)Study completedNCT02975934
What this trial is testing

Rucaparib Versus Physician's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency

Who this might be right for
Metastatic Castration Resistant Prostate Cancer
pharmaand GmbH 405
Testing effectiveness (Phase 2)Active Not RecruitingNCT03012321
What this trial is testing

Abiraterone/Prednisone, Olaparib, or Abiraterone/Prednisone + Olaparib in Patients With Metastatic Castration-Resistant Prostate Cancer With DNA Repair Defects

Who this might be right for
Prostate Cancer Metastatic Castration-ResistantAbnormal DNA RepairMetastatic Prostate Carcinoma+1 more
Northwestern University 70
Early research (Phase 1)Study completedNCT04179396
What this trial is testing

Study of Oral Rucaparib With Other Anticancer Agents in Metastatic Castration Resistant Prostate Cancer Patients (RAMP)

Who this might be right for
Metastatic Castration Resistant Prostate Cancer
pharmaand GmbH 8
Not applicableEnrolling By InvitationNCT06938542
What this trial is testing

Palliative Care Needs of Children With Rare Diseases and Their Families

Who this might be right for
Trisomy 13 SyndromeArthrogryposis Congenita Multiplex With Intestinal AtresiaAsparagine Synthetase Deficiency+16 more
Children's National Research Institute 480
Not applicableLooking for participantsNCT01793168
What this trial is testing

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Who this might be right for
Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more
Sanford Health 20,000
Testing effectiveness (Phase 2)Ended earlyNCT03397394
What this trial is testing

Rucaparib in Patients With Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Bladder CancerUrothelial CarcinomaMetastatic Urothelial Carcinoma+5 more
pharmaand GmbH 97