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Results for “DNA Repair-Deficiency Disorders”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT02052908
What this trial is testing

Naproxen in Preventing DNA Mismatch Repair Deficient Colorectal Cancer in Patients With Lynch Syndrome

Who this might be right for
Lynch Syndrome
National Cancer Institute (NCI) 81
Not applicableLooking for participantsNCT07077447
What this trial is testing

The Danish Bladder Cancer Group 23 Study - A European Study on Cancer in the Upper Urinary Tract

Who this might be right for
Upper Urinary Tract Urothelial Carcinoma
Zealand University Hospital 2,500
Testing effectiveness (Phase 2)UnknownNCT03831698
What this trial is testing

Omega 3 Fatty Acids in Colorectal Cancer (CRC) Prevention in Patients With Lynch Syndrome (COLYNE)

Who this might be right for
Colorectal CancerLynch Syndrome
University of Kansas Medical Center 21
Testing effectiveness (Phase 2)Ended earlyNCT05405309
What this trial is testing

RP-3500 and Olaparib in DNA Damage Repair Pathway Deficient Relapsed/Refractory Chronic Lymphocytic Leukemia

Who this might be right for
Chronic Lymphocytic Leukemia
University of Utah 5
Not applicableWithdrawnNCT04656171
What this trial is testing

Microcephaly, Fanconi Anemia and Praxial Disorders

Who this might be right for
Fanconi Anemia
Assistance Publique - Hôpitaux de Paris
Testing effectiveness (Phase 2)Ended earlyNCT03875313
What this trial is testing

Study of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid Tumors

Who this might be right for
Solid TumorClear Cell Renal Cell CarcinomaTNBC - Triple-Negative Breast Cancer+4 more
Calithera Biosciences, Inc 33
Early research (Phase 1)Looking for participantsNCT07163403
What this trial is testing

First in Human Pilot Study to Assess the Safety and Efficacy of Dendritic Cells Loaded With Frameshift Derived Neopeptides for the Prevention of Cancer in of Lynch Syndrome Carriers

Who this might be right for
Lynch Syndrome
Fundacion Clinic per a la Recerca Biomédica 20
Not applicableUnknownNCT04909671
What this trial is testing

Evaluation of ArTificial Intelligence System (Gi-Genius) for adenoMa dEtection in Lynch Syndrome.

Who this might be right for
Lynch Syndrome
Hospital Clinic of Barcelona 404
Not applicableStudy completedNCT02645084
What this trial is testing

Identifying Patients With Hereditary and Familial Colorectal Cancer by Using an Online Risk Tool

Who this might be right for
Colorectal CancerLynch SyndromeFamilial Colorectal Cancer
Prof. Evelien Dekker, MD, PhD 104
Not applicableLooking for participantsNCT07498829
What this trial is testing

Population Based Germline Testing for Early Detection and Prevention of Cancer

Who this might be right for
Breast Cancer RiskOvarian Cancer RiskCancer Gene Mutation
Queen Mary University of London 6,000
Large-scale testing (Phase 3)Active Not RecruitingNCT02813824
What this trial is testing

Effect of Chemoprevention by Low-dose Aspirin of New or Recurrent Colorectal Adenomas in Patients With Lynch Syndrome

Who this might be right for
Lynch Syndrome
Assistance Publique - Hôpitaux de Paris 852
Not applicableNot Yet RecruitingNCT07542405
What this trial is testing

A Web-Based Program (Kindred) to Improve the Understanding of Genetic Cancer Risk and Cancer Genetic Testing in African American Families

Who this might be right for
BRCA1-Related Hereditary Breast and Ovarian Cancer SyndromeBRCA2-Related Hereditary Breast and Ovarian Cancer SyndromeHereditary Neoplastic Syndrome+1 more
University of Michigan Rogel Cancer Center 150
Testing effectiveness (Phase 2)Looking for participantsNCT07284641
What this trial is testing

Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)

Who this might be right for
Common Variable Immunodeficiency (CVID)Primary Immune Regulatory DisorderImmune Dysregulation+12 more
Paul Szabolcs 25
Not applicableStudy completedNCT01565005
What this trial is testing

Microcephaly Genetic Deficiency in Neural Progenitors

Who this might be right for
Microcephaly
Assistance Publique - Hôpitaux de Paris 98
Not applicableStudy completedNCT04407611
What this trial is testing

Scalable Communication Modalities for Returning Genetic Research Results

Who this might be right for
Hereditary Breast and Ovarian CancerLynch Syndrome
Boston University 926
Not applicableLooking for participantsNCT03124212
What this trial is testing

Cascade Genetic Testing for Hereditary Breast/Ovarian Cancer and Lynch Syndrome in Switzerland

Who this might be right for
Hereditary Breast and Ovarian CancerLynch Syndrome
University of Basel 700
Testing effectiveness (Phase 2)UnknownNCT04887311
What this trial is testing

MBM-01 (Tempol) for the Treatment of Ataxia Telangiectasia

Who this might be right for
Ataxia Telangiectasia Louis-BarAtaxia Telangiectasia in ChildrenAtaxia Telangiectasia
Matrix Biomed, Inc. 20
Not applicableEnrolling By InvitationNCT01186913
What this trial is testing

Natural History Study of SCID Disorders

Who this might be right for
Severe Combined Immunodeficiency (SCID)Leaky SCIDOmenn Syndrome+3 more
National Institute of Allergy and Infectious Diseases (NIAID) 690
Very early researchWithdrawnNCT06246786
What this trial is testing

Breast/Cyclosporin A/TNBC (Triple Negative Breast Cancer)

Who this might be right for
Triple Negative Breast CancerDNA Damage Repair Deficiency
Virginia G. Kaklamani
Not applicableStudy completedNCT03460483
What this trial is testing

Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized Care

Who this might be right for
Endometrial AdenocarcinomaEndometrial CarcinomaLynch Syndrome+1 more
Ohio State University Comprehensive Cancer Center 1,001
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