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Results for “Damage Dna”

174 trials

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Showing 20 of 174 results

Testing effectiveness (Phase 2)Study completedNCT04740190
What this trial is testing

Talazoparib - Carboplatin for Recurrent High-grade Glioma With DDRd

Who this might be right for
Recurrent GliomaRecurrent GlioblastomaPoly ADP Ribose Polymerase (PARP) Inhibitor+2 more
The University of Hong Kong 33
Testing effectiveness (Phase 2)Active Not RecruitingNCT04711824
What this trial is testing

Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases

Who this might be right for
Breast CancerBrain Metastases, Adult
Colette Shen 41
Testing effectiveness (Phase 2)Active Not RecruitingNCT04266912
What this trial is testing

Avelumab and M6620 for the Treatment of DDR Deficient Metastatic or Unresectable Solid Tumors

Who this might be right for
Metastatic Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
M.D. Anderson Cancer Center 23
Not applicableStudy completedNCT01462448
What this trial is testing

Study to Identify the Genetic Variations Associated With Phantom Limb Pain

Who this might be right for
Phantom Limb
Henry M. Jackson Foundation for the Advancement of Military Medicine 726
Early research (Phase 1)Study completedNCT04158336
What this trial is testing

Azenosertib (ZN-c3) in Participants With Solid Tumors

Who this might be right for
Solid Tumor
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc 274
Not applicableStudy completedNCT02310087
What this trial is testing

Oral Astaxanthin and Semen Quality, Fertilization and Embryo Development in Assisted Reproduction Techniques Procedures

Who this might be right for
Infertility, Male
University Medical Centre Ljubljana 80
Not applicableStudy completedNCT03944421
What this trial is testing

The Effects of Replacing Red and Processed Meat With Quorn on Biomarkers of Gut Health

Who this might be right for
Colorectal Cancer
Northumbria University 20
Not applicableActive Not RecruitingNCT07479940
What this trial is testing

Obesity and Aging: Impacts of Nutritional Counseling and Physical Exercise on Telomeres and Senescence Parameters

Who this might be right for
AgingObesityNutrition+5 more
University of Sao Paulo 60
Not applicableUnknownNCT06204523
What this trial is testing

Prospective Validation of a DNA Damage Repair-Hippo Pathway Signature in Patients With Advanced Gastric Cancer

Who this might be right for
DNA DamageGastric Cancer
Regina Elena Cancer Institute 167
Testing effectiveness (Phase 2)Study completedNCT04564027
What this trial is testing

A Study Investigating DNA-damage Response Agents in Molecularly Altered Advanced Cancer

Who this might be right for
Advanced Solid Tumours
AstraZeneca 54
Not applicableStudy completedNCT01644279
What this trial is testing

Skeletal Muscle Apoptosis and Physical Performance; Oxidative RNA/DNA Damage and Repair in Aged Human Muscle

Who this might be right for
Sarcopenia
University of Florida 63
Not applicableStudy completedNCT02335086
What this trial is testing

DNA Damage & Repair Proteins In Patients With Atherosclerotic Coronary Artery Disease

Who this might be right for
Coronary Atherosclerosis
University of Surrey 126
Testing effectiveness (Phase 2)Study completedNCT03554473
What this trial is testing

M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers

Who this might be right for
Carcinoma, Small CellLung CancerSmall Cell Lung Cancer
National Cancer Institute (NCI) 37
Testing effectiveness (Phase 2)Study completedNCT02487095
What this trial is testing

Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers

Who this might be right for
Carcinoma, Non-Small -Cell LungOvarian NeoplasmsSmall Cell Lung Carcinoma+3 more
National Cancer Institute (NCI) 62
Testing effectiveness (Phase 2)Active Not RecruitingNCT05515575
What this trial is testing

Niraparib in People With Soft Tissue Sarcoma Who Have Changes in Their Tumor DNA

Who this might be right for
Sarcoma,Soft TissueSarcoma Uterus
Memorial Sloan Kettering Cancer Center 8
Not applicableUnknownNCT05277961
What this trial is testing

Quantification of DNA Repair Products in the Urine After Ultraviolet Radiation of the Skin

Who this might be right for
Ultraviolet Rays; InjuryDNA Adduct FormationDNA Damage, Radiation Induced+1 more
Bispebjerg Hospital 80
Post-approval studies (Phase 4)Study completedNCT03945955
What this trial is testing

Melatonin and DNA Damage Study

Who this might be right for
Sleep QualityDNA Damage Repair DeficiencyOxidative Stress
University of British Columbia 40
Testing effectiveness (Phase 2)Study completedNCT03448718
What this trial is testing

Trial of Olaparib in Patients With Metastatic Urothelial Cancer Harboring DNA Damage Response Gene Alterations

Who this might be right for
Metastatic Urothelial Cancer
Matthew Galsky 19
Testing effectiveness (Phase 2)UnknownNCT04761744
What this trial is testing

A Phase II Study of Nivolumab in Patients With Genetic Alterations in DNA Damage Repair and Response Who Progressed After Standard Treatment for Metastatic Solid Cancers

Who this might be right for
DDR Gene MutationMetastatic Solid Tumor
Korean Cancer Study Group 48
Early research (Phase 1)Study completedNCT03704467
What this trial is testing

Phase Ib/II Study of Carboplatin + M6620 + Avelumab in PARPi-resistant Ovarian Cancer

Who this might be right for
Ovarian Cancer
EMD Serono Research & Development Institute, Inc. 3
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