Not applicableUnknownNCT04160208What this trial is testingDNA Damage and Subfertility in Males - Impact on ART OutcomeWho this might be right forInfertility Regionshospitalet Viborg, Skive 1,350
Testing effectiveness (Phase 2)UnknownNCT05461261What this trial is testingThe Efficacy and Safety of Docetaxel Combined With Platinum for Metastatic Hormone-sensitive Prostate CancerWho this might be right forHormone Sensitive Metastatic Prostate CancerDNA Damage Repair DeficiencyChemotherapy Effect+1 more The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 50
Not applicableStudy completedNCT02922790What this trial is testingFeasibility and Smokers' Reactions to DNA FeedbackWho this might be right forSmoking Duke University 39
Testing effectiveness (Phase 2)Looking for participantsNCT03740893What this trial is testingPHOENIX DDR/Anti-PD-L1 Trial: A Pre-surgical Window of Opportunity and Post-surgical Adjuvant Biomarker Study of DNA Damage Response Inhibition With or Without Anti-PD-L1 Immunotherapy in Patients With Neoadjuvant Treatment Resistant Residual Triple Negative Breast CancerWho this might be right forBreast NeoplasmTriple Negative Breast Cancer (TNBC)HRD Institute of Cancer Research, United Kingdom 119
Not applicableStudy completedNCT05094960What this trial is testingMeasurement of Circulating Cell-free DNA (cfDNA) for Diagnosis and Prognosis of Various Diseases and Evaluation of Tissue DamageWho this might be right forCorrelation of cFDNA During CPB to Laboratories SIRS Parameters and Clinical Outcomes Soroka University Medical Center 71
Large-scale testing (Phase 3)Looking for participantsNCT06439225What this trial is testingPlatinum and Taxane Chemo in Met Castration Resistant Prostate Cancer Patients With Alterations in DNA Damage Response GenesWho this might be right forMetastatic Castration-resistant Prostate CancerMetastatic Prostate Cancer Canadian Cancer Trials Group 236
Early research (Phase 1)Looking for participantsNCT05687110What this trial is testingStudying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair GenesWho this might be right forMetastatic Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm National Cancer Institute (NCI) 43
Post-approval studies (Phase 4)WithdrawnNCT01717846What this trial is testingEffect on Orencia (Abatacept) on the Apoptosis of T Cells, B Cells and APC Cells in Rheumatoid ArthritisWho this might be right forApoptotic DNA DamageRheumatoid ArthritisT-cell Lymphocytosis University of California, Los Angeles
Very early researchUnknownNCT04781868What this trial is testingMulti-Nutrient Supplement for Radio-ProtectionWho this might be right forOxidative StressDNA Damage, Radiation InducedRadiation Exposure McMaster University 30
Early research (Phase 1)Study completedNCT00553189What this trial is testingSafety Study of ABT-888 Plus Topotecan Hydrochloride to Treat Patients With Solid Tumors and LymphomasWho this might be right forSolid TumorsLymphomas National Cancer Institute (NCI) 31
Early research (Phase 1)Study completedNCT02630199What this trial is testingStudy of AZD6738, DNA Damage Repair/Novel Anti-cancer Agent, in Combination With Paclitaxel, in Refractory CancerWho this might be right forRefractory Cancer Samsung Medical Center 65
Not applicableLooking for participantsNCT06999785What this trial is testingAssessment of the Impact of Increased Production of Reactive Oxygen Species Produced During Repeated Sessions of Hyperbaric Oxygen Therapy in Patients Undergoing Radiotherapy for Neoplasia, on the Occurrence of DNA DamageWho this might be right forHyperbaric OxygenGenotoxicityMalignancy University Hospital, Angers 60
Not applicableStudy completedNCT07660003What this trial is testing8-OHdG and Oxidative Stress in Febrile SeizuresWho this might be right forFebrile SeizuresOxidative StressOxidative DNA Damage Kayseri City Hospital 156
Not applicableStudy completedNCT07279896What this trial is testingDetermination of RNA/DNA Damage Associated With Oxidative Stress in Periodontitis PatientsWho this might be right forPeriodontitis (Stage 3)Smoking Zehra Hasgül 88
Not applicableStudy completedNCT03284632What this trial is testingE-Cigarette - DNA AdductsWho this might be right forSmokingCigarette SmokingElectronic Cigarettes University of Minnesota 217
Testing effectiveness (Phase 2)WithdrawnNCT04655183What this trial is testingStudy of M4344 in Combination With NiraparibWho this might be right forAdvanced Solid TumorBreast Cancer EMD Serono Research & Development Institute, Inc.
Not applicableUnknownNCT03345030What this trial is testingThe Role of DNA Damage of Granulosa Cell on Oocyte Quality and in Vitro Fertilization OutcomeWho this might be right forin Vitro Fertilization Suleyman Demirel University 60
Testing effectiveness (Phase 2)Study completedNCT01994707What this trial is testingRemote Ischemic Preconditioning of Human MyocardiumWho this might be right forCoronary Artery Bypass Graft Triple VesselApoptotic DNA Damage Medical University of Silesia 134
Not applicableUnknownNCT02231736What this trial is testingChromosomal Damage in Type 2 Diabetes Patients (MIKRODIAB)Who this might be right forType 2 DiabetesCancer University of Vienna 130
Testing effectiveness (Phase 2)Active Not RecruitingNCT03609216What this trial is testingGemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic AlterationsWho this might be right forInfiltrating Bladder Urothelial CarcinomaStage II Bladder Urothelial CarcinomaStage III Bladder Urothelial Carcinoma Alliance for Clinical Trials in Oncology 237