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Results for “Degenerative Diseases of the Central Nervous System”

459 trials

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Showing 20 of 459 results

Not applicableStudy completedNCT00344890
What this trial is testing

Safety Study of Preservon-Treated Bone Implants for Cervical Fusion in the Treatment of Cervical Radiculopathy or Myelopathy

Who this might be right for
Cervical RadiculopathyMyelopathy
LifeNet Health 106
Testing effectiveness (Phase 2)Active Not RecruitingNCT04408625
What this trial is testing

Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)

Who this might be right for
Frontotemporal Dementia
Prevail Therapeutics 35
Large-scale testing (Phase 3)Ended earlyNCT04378075
What this trial is testing

Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy

Who this might be right for
Mitochondrial DiseasesDrug Resistant EpilepsyLeigh Disease+5 more
PTC Therapeutics 68
Not applicableLooking for participantsNCT05296889
What this trial is testing

Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Cervical

Who this might be right for
Spine FractureDegenerative Disc DiseaseSpinal Instability+2 more
Aesculap AG 200
Not applicableUnknownNCT00999934
What this trial is testing

Neural Mechanisms Engaged in Control of Eye Movements

Who this might be right for
Degenerative Diseases of the Central Nervous SystemOcular-motor and Vestibular Diseases
Meir Medical Center 250
Not applicableNot Yet RecruitingNCT06663878
What this trial is testing

An Exploratory Study to Evaluate the Tolerability and Safety of MWAV201 in Subjects With Wilson Disease

Who this might be right for
Wilson Disease
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 9
Testing effectiveness (Phase 2)Active Not RecruitingNCT05893225
What this trial is testing

Metformin Add-on Clinical Study in Multiple Sclerosis to Evaluate Brain Remyelination And Neurodegeneration

Who this might be right for
Multiple SclerosisPrimary Progressive Multiple SclerosisSecondary-progressive Multiple Sclerosis
University Hospital, Antwerp 120
Early research (Phase 1)Study completedNCT03347708
What this trial is testing

Study to Evaluate the Safety and Preliminary Efficacy of IDCT, a Treatment for Symptomatic Lumbar Intervertebral Disc Degeneration

Who this might be right for
Degenerative Disc Disease
DiscGenics, Inc. 60
Testing effectiveness (Phase 2)Study completedNCT04032626
What this trial is testing

MCLENA-1: A Clinical Trial for the Assessment of Lenalidomide in Amnestic MCI Patients

Who this might be right for
Cognitive Impairment, MildCognitive DysfunctionAmyloid Plaque+2 more
St. Joseph's Hospital and Medical Center, Phoenix 15
Early research (Phase 1)UnknownNCT00674960
What this trial is testing

Far Infrared Irradiation for the Management, Control and Treatment of Frontotemporal Dementia

Who this might be right for
Pick Disease of the Brain
GAAD Medical Research Institute Inc.
Not applicableStudy completedNCT04578691
What this trial is testing

Study to Evaluate the Safety and Clinical Outcome of Using Navigation System in Pedicle Screw Placement in Spine Surgery

Who this might be right for
Spinal TumorTraumatic Injury of SpineDegenerative Spine Disease
Taipei Veterans General Hospital, Taiwan 55
Testing effectiveness (Phase 2)Study completedNCT02445794
What this trial is testing

A First in Human Study of RT001 in Patients With Friedreich's Ataxia

Who this might be right for
Friedreich's Ataxia
Biojiva LLC 19
Not applicableStudy completedNCT03683875
What this trial is testing

Ultrasonography of the Neuromuscular Degeneration Behavior in Amyotrophic Lateral Sclerosis

Who this might be right for
Amyotrophic Lateral Sclerosis
Hospital General Universitario Santa Lucia 26
Not applicableStudy completedNCT02966145
What this trial is testing

4-Repeat Tauopathy Neuroimaging Initiative - Cycle 2

Who this might be right for
Corticobasal Degeneration (CBD)Corticobasal Syndrome (CBS)Cortical-basal Ganglionic Degeneration (CBGD)+3 more
University of California, San Francisco 293
Early research (Phase 1)UnknownNCT03174886
What this trial is testing

A 24-month Phase 1 Pilot Study of AADvac1 in Patients With Non Fluent Primary Progressive Aphasia

Who this might be right for
Primary Progressive Nonfluent Aphasia
Axon Neuroscience SE 33
Not applicableStudy completedNCT05502432
What this trial is testing

Repetitive Transcranial Magnetic Stimulation in SCA3 Patients

Who this might be right for
Spinocerebellar Ataxia Type 3
Ning Wang, MD., PhD. 39
Early research (Phase 1)Study completedNCT06705192
What this trial is testing

Study in Asymptomatic GRN-FTD Patients to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VES001

Who this might be right for
DementiaFrontotemporal DementiaAsymptomatic Condition
Mads Kjolby 6
Not applicableLooking for participantsNCT04679844
What this trial is testing

Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion

Who this might be right for
Degenerative Disc DiseaseSpine FusionBack Pain
Kuros Biosurgery AG 60
Not applicableNot Yet RecruitingNCT06089863
What this trial is testing

Rehabilitation Program on Genetic and Degenerative Ataxia

Who this might be right for
AtaxiaDegenerative DiseaseGenetic Disease
Hospices Civils de Lyon 48
Large-scale testing (Phase 3)Active Not RecruitingNCT05515536
What this trial is testing

Assess the Safety and Efficacy of Vatiquinone in Participants With Friedreich Ataxia

Who this might be right for
Friedreich Ataxia
PTC Therapeutics 130
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