Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Demyelinating Diseases of the Central Nervous System”

652 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 652 results

Not applicableEnded earlyNCT02493491
What this trial is testing

Neurogenic Dysphonia/Dysphagia Registry

Who this might be right for
Neurogenic DysphoniaNeurogenic Dysphagia
Merz North America, Inc. 146
Large-scale testing (Phase 3)Ended earlyNCT04378075
What this trial is testing

Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy

Who this might be right for
Mitochondrial DiseasesDrug Resistant EpilepsyLeigh Disease+5 more
PTC Therapeutics 68
Early research (Phase 1)Looking for participantsNCT06150716
What this trial is testing

Orbit Study: A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Intrathecally Administered ION356 in Participants With Pelizaeus Merzbacher Disease (PMD)

Who this might be right for
Pelizaeus-Merzbacher Disease
Ionis Pharmaceuticals, Inc. 24
Not applicableStudy completedNCT05435404
What this trial is testing

Qualitative Study Patient & Physician Experiences Botox COVID-19

Who this might be right for
Chronic Brain InjuryCerebral StrokeMS (Multiple Sclerosis)
East Kent Hospitals University NHS Foundation Trust 11
Testing effectiveness (Phase 2)Active Not RecruitingNCT05893225
What this trial is testing

Metformin Add-on Clinical Study in Multiple Sclerosis to Evaluate Brain Remyelination And Neurodegeneration

Who this might be right for
Multiple SclerosisPrimary Progressive Multiple SclerosisSecondary-progressive Multiple Sclerosis
University Hospital, Antwerp 120
Not applicableActive Not RecruitingNCT04369976
What this trial is testing

Short Arm Human Centrifuge Therapeutic Training and Rehabilitation (GRACER1)

Who this might be right for
Multiple SclerosisStrokePulmonary Disease, Chronic Obstructive+1 more
Greek Aerospace Medical Association and Space Research 105
Not applicableNot Yet RecruitingNCT07150520
What this trial is testing

VR-Based Optokinetic Stimulation in Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Avrasya University 30
Testing effectiveness (Phase 2)Study completedNCT00333138
What this trial is testing

Efficacy and Safety of FTY720 in Patients With Relapsing Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Novartis 281
Not applicableUnknownNCT01811290
What this trial is testing

A Pilot Study Assessing the Impact of Gilenya Therapy on Bone Density Change in Relapsing Forms of Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Simnad, Virginia, M.D. 36
Not applicableStudy completedNCT04893590
What this trial is testing

Adapting MHealth Technology to Improve Patient Activation

Who this might be right for
Spinal Cord InjuriesStrokeMultiple Sclerosis
Washington University School of Medicine 27
Large-scale testing (Phase 3)Study completedNCT01167426
What this trial is testing

Evaluation of Two Glatiramer Acetate (GA) Formulations in Relapsing-Remitting Multiple Sclerosis (RRMS) Patients

Who this might be right for
Multiple Sclerosis
Teva Neuroscience, Inc. 148
Not applicableEnded earlyNCT03387267
What this trial is testing

Videofluoroscopic Swallowing Study (VFSS)

Who this might be right for
StrokeParkinson DiseaseMultiple Sclerosis+3 more
Société des Produits Nestlé (SPN) 452
Not applicableTemporarily pausedNCT04031469
What this trial is testing

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease

Who this might be right for
Gut MicrobiomeGastrointestinal MicrobiomeAutism+77 more
ProgenaBiome 1,000
Testing effectiveness (Phase 2)Looking for participantsNCT07085507
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VT7208 in Healthy Participants and MS Patients

Who this might be right for
Multiple Sclerosis
Vidya Therapeutics Inc 100
Large-scale testing (Phase 3)Looking for participantsNCT05346354
What this trial is testing

Efficacy and Safety Study of Ravulizumab IV in Pediatric Participants With NMOSD

Who this might be right for
Neuromyelitis Optica Spectrum Disorder
Alexion Pharmaceuticals, Inc. 12
Testing effectiveness (Phase 2)WithdrawnNCT02715505
What this trial is testing

Safety and Exploratory Efficacy of HSC835 in Patients With Inherited Metabolic Disorders (IMD)

Who this might be right for
Inherited Metabolic Disorders IMD
Novartis Pharmaceuticals
Not applicableEnded earlyNCT02204904
What this trial is testing

Observational Study to Evaluate Allogeneic HSCT Outcomes for Cerebral Adrenoleukodystrophy (CALD)

Who this might be right for
X-Linked Adrenoleukodystrophy (X-ALD)Cerebral Adrenoleukodystrophy (CALD)Adrenoleukodystrophy (ALD)
Genetix Biotherapeutics Inc. 59
Testing effectiveness (Phase 2)UnknownNCT05541549
What this trial is testing

Study Evaluating JCPyV-specific T Cell Therapy for PML

Who this might be right for
Progressive Multifocal Leukoencephalopathy
Cellevolve Bio Inc 60
Testing effectiveness (Phase 2)Study completedNCT01056471
What this trial is testing

Autologous Mesenchymal Stem Cells From Adipose Tissue in Patients With Secondary Progressive Multiple Sclerosis

Who this might be right for
Autoimmune DiseasesImmune System DiseasesDemyelinating Diseases+3 more
Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud 30
Post-approval studies (Phase 4)Study completedNCT01705236
What this trial is testing

A 3-year Multi-center Study to Describe Changes of OCT Parameters Under Treatment With Gilenya®

Who this might be right for
Relapsing Remitting Multiple Sclerosis RRMS
Novartis Pharmaceuticals 87
Load More Results