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Results for “Developmental and Epileptic Encephalopathies”

50 trials

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Showing 20 of 50 results

Testing effectiveness (Phase 2)Looking for participantsNCT06401538
What this trial is testing

BMB-101 in Absence Epilepsy and DEE

Who this might be right for
Absence EpilepsyJeavons SyndromeDravet Syndrome+1 more
Bright Minds Biosciences Pty Ltd 20
Testing effectiveness (Phase 2)Study completedNCT05626634
What this trial is testing

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

Who this might be right for
Developmental and Epileptic EncephalopathyDravet SyndromeLennox-Gastaut Syndrome
Longboard Pharmaceuticals 41
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Testing effectiveness (Phase 2)UnknownNCT03944447
What this trial is testing

Outcomes Mandate National Integration With Cannabis as Medicine

Who this might be right for
Chronic PainChronic Pain SyndromeChronic Pain Due to Injury+30 more
OMNI Medical Services, LLC 200,000
Large-scale testing (Phase 3)Active Not RecruitingNCT05818553
What this trial is testing

A Clinical Trial of PRAX-562 in Subjects With Developmental and Epileptic Encephalopathies (DEE)

Who this might be right for
SCN2A EncephalopathySCN8A Encephalopathy
Praxis Precision Medicines 77
Testing effectiveness (Phase 2)Looking for participantsNCT05419492
What this trial is testing

A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome

Who this might be right for
Dravet Syndrome
Encoded Therapeutics 47
Testing effectiveness (Phase 2)Study completedNCT05364021
What this trial is testing

Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies

Who this might be right for
Developmental and Epileptic EncephalopathyDravet SyndromeLennox Gastaut Syndrome
Longboard Pharmaceuticals 52
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07221968
What this trial is testing

Melatonin for the Treatment of DEE-SWAS

Who this might be right for
CSWSDevelopmental and/or Epileptic EncephalopathiesElectrical Status Epilepticus in Sleep
Hugo W. Moser Research Institute at Kennedy Krieger, Inc. 3
Not applicableNot Yet RecruitingNCT07396883
What this trial is testing

Developmental and Epileptic Encephalopathies Diagnosed Via Long-read Genome Sequencing

Who this might be right for
Developmental and Epileptic EncephalopathyEpilepsy in Children
University Hospital, Strasbourg, France 20
Not applicableNot Yet RecruitingNCT07531511
What this trial is testing

SLC6A1-NDD Prospective Longitudinal Natural History Study

Who this might be right for
SLC6A1 Neurodevelopmental Disorder (NDD)Developmental and Epileptic Encephalopathies
UCB Biopharma SRL 60
Very early researchActive Not RecruitingNCT04937062
What this trial is testing

Phenylbutyrate for Monogenetic Developmental and Epileptic Encephalopathy

Who this might be right for
STXBP1 Encephalopathy With Epilepsy, SLC6A1 Neurodevelopmental DisorderDevelopmental and Epileptic Encephalopathy
Weill Medical College of Cornell University 50
Testing effectiveness (Phase 2)Study completedNCT03650452
What this trial is testing

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Participants With Developmental and/or Epileptic Encephalopathies

Who this might be right for
EpilepsyDravet SyndromeLennox-Gastaut Syndrome
Takeda 141
Large-scale testing (Phase 3)Looking for participantsNCT07019922
What this trial is testing

A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

Who this might be right for
Epileptic EncephalopathySCN2A Encephalopathy
Praxis Precision Medicines 40
Testing effectiveness (Phase 2)Ended earlyNCT05226780
What this trial is testing

Extension Study to Evaluate How Safe and Tolerable NBI-921352 is as an Adjunctive Therapy for Participants With SCN8A-DEE

Who this might be right for
SCN8A Developmental and Epileptic Encephalopathy Syndrome
Neurocrine Biosciences 8
Not applicableStudy completedNCT04337697
What this trial is testing

Neonatal Seizure Registry - Developmental Functional EValuation

Who this might be right for
Neonatal SeizureHypoxic-Ischemic EncephalopathyStroke+4 more
University of California, San Francisco 188
Not applicableLooking for participantsNCT01238250
What this trial is testing

Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight

Who this might be right for
16P11.2 Deletion Syndrome16p11.2 Duplications1Q21.1 Deletion+181 more
Simons Searchlight 100,000
Post-approval studies (Phase 4)UnknownNCT05232630
What this trial is testing

Fenfluramine for the Treatment of Different Types of Developmental and Epileptic Encephalopathies: a Pilot Trial Exploring Epileptic and Non-epileptic Outcomes

Who this might be right for
Refractory EpilepsySYNGAP1 EncephalopathySTXBP1 Encephalopathy With Epilepsy+3 more
Hospital Ruber Internacional 20
Not applicableLooking for participantsNCT06500260
What this trial is testing

CNKSR2 Natural History Study

Who this might be right for
Developmental DysphasiaEpileptic Encephalopathy, Childhood-OnsetX-Linked Intellectual Disability
University of California, San Francisco 15
Not applicableLooking for participantsNCT06278428
What this trial is testing

Genotype, Phenotype, and Disease Progression of Developmental Epileptic Encephalopathy With Onset Before 2 Years of Age

Who this might be right for
Epilepsy; SeizureChild DevelopmentGene Abnormality+1 more
Number 2 Children's Hospital, Ho Chi Minh City 50
Early research (Phase 1)Looking for participantsNCT06700811
What this trial is testing

Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies

Who this might be right for
Developmental and Epileptic EncephalopathiesEpileptic SpasmsGenetic Epilepsy+1 more
Heather Olson 10
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