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Results for “Developmental and Epileptic Encephalopathies”

51 trials

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Showing 20 of 51 results

Large-scale testing (Phase 3)Ended earlyNCT04639310
What this trial is testing

XEN496 (Ezogabine) in Children With KCNQ2 Developmental and Epileptic Encephalopathy

Who this might be right for
EpilepsyEpilepsy in ChildrenEpilepsy; Seizure+5 more
Xenon Pharmaceuticals Inc. 8
Large-scale testing (Phase 3)Active Not RecruitingNCT06660394
What this trial is testing

A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)

Who this might be right for
Dravet Syndrome
Longboard Pharmaceuticals 96
Large-scale testing (Phase 3)Not Yet RecruitingNCT07723976
What this trial is testing

Evaluate the Safety and Efficacy of CBD-OS in Participants With DEE

Who this might be right for
Developmental and Epileptic Encephalopathy (DEE)
Jazz Pharmaceuticals 120
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Not applicableActive Not RecruitingNCT06500260
What this trial is testing

CNKSR2 Natural History Study

Who this might be right for
Developmental DysphasiaEpileptic Encephalopathy, Childhood-OnsetX-Linked Intellectual Disability
University of California, San Francisco 20
Large-scale testing (Phase 3)Active Not RecruitingNCT05818553
What this trial is testing

A Clinical Trial of PRAX-562 in Subjects With Developmental and Epileptic Encephalopathies (DEE)

Who this might be right for
SCN2A EncephalopathySCN8A Encephalopathy
Praxis Precision Medicines 77
Testing effectiveness (Phase 2)Looking for participantsNCT06401538
What this trial is testing

BMB-101 in Absence Epilepsy and DEE

Who this might be right for
Absence EpilepsyJeavons SyndromeDravet Syndrome+1 more
Bright Minds Biosciences Pty Ltd 20
Not applicableLooking for participantsNCT06278428
What this trial is testing

Genotype, Phenotype, and Disease Progression of Developmental Epileptic Encephalopathy With Onset Before 2 Years of Age

Who this might be right for
Epilepsy; SeizureChild DevelopmentGene Abnormality+1 more
Number 2 Children's Hospital, Ho Chi Minh City 50
Not applicableEnded earlyNCT04537832
What this trial is testing

Natural History Study of Infants and Children With Developmental and Epileptic Encephalopathies

Who this might be right for
Dravet Syndrome
Encoded Therapeutics 58
Not applicableNot Yet RecruitingNCT07585643
What this trial is testing

IBIS - Investigating Reliability of BIS and SEDLINE Monitoring in Children With Developmental and Epileptic Encephalopathies (DEE).

Who this might be right for
Epileptic EncephalopathyEarly Infantile Epileptic EncephalopathyInfantile Spasm+1 more
Telethon Kids Institute 40
Testing effectiveness (Phase 2)Ended earlyNCT03635073
What this trial is testing

Soticlestat in Adults and Children With Rare Epilepsies

Who this might be right for
EpilepsyDravet Syndrome (DS)Lennox-Gastaut Syndrome (LGS)
Takeda 156
Testing effectiveness (Phase 2)Ended earlyNCT04873869
What this trial is testing

Study to Evaluate NBI-921352 as Adjunctive Therapy in Subjects With SCN8A Developmental and Epileptic Encephalopathy Syndrome (SCN8A-DEE)

Who this might be right for
SCN8A Developmental and Epileptic Encephalopathy Syndrome
Neurocrine Biosciences 8
Not applicableStudy completedNCT03525431
What this trial is testing

Clinical Utility of Pediatric Whole Exome Sequencing

Who this might be right for
EncephalopathyBirth DefectIntellectual Disability+7 more
University of California, San Francisco 529
Very early researchLooking for participantsNCT07675746
What this trial is testing

Evaluate the Safety and Pharmacokinetics of RC001 in Children With Dravet Syndrome

Who this might be right for
Dravet Syndrome (DS)
Second Affiliated Hospital of Guangzhou Medical University 8
Testing effectiveness (Phase 2)Study completedNCT05626634
What this trial is testing

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

Who this might be right for
Developmental and Epileptic EncephalopathyDravet SyndromeLennox-Gastaut Syndrome
Longboard Pharmaceuticals 41
Large-scale testing (Phase 3)Ended earlyNCT04912856
What this trial is testing

An Open-Label Extension of the Study XEN496 (Ezogabine) in Children With KCNQ2-DEE

Who this might be right for
EpilepsyEpilepsy in ChildrenEpilepsy; Seizure+5 more
Xenon Pharmaceuticals Inc. 8
Testing effectiveness (Phase 2)Ended earlyNCT05226780
What this trial is testing

Extension Study to Evaluate How Safe and Tolerable NBI-921352 is as an Adjunctive Therapy for Participants With SCN8A-DEE

Who this might be right for
SCN8A Developmental and Epileptic Encephalopathy Syndrome
Neurocrine Biosciences 8
Not applicableLooking for participantsNCT07531511
What this trial is testing

SLC6A1-NDD Prospective Longitudinal Natural History Study

Who this might be right for
SLC6A1 Neurodevelopmental Disorder (NDD)Developmental and Epileptic Encephalopathies (DEE)
UCB Biopharma SRL 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT05737784
What this trial is testing

A Clinical Trial of PRAX-222 in Pediatric Participants With Early Onset SCN2A Developmental and Epileptic Encephalopathy

Who this might be right for
SCN2A-DEEEpilepsy
Praxis Precision Medicines 60
Testing effectiveness (Phase 2)UnknownNCT03944447
What this trial is testing

Outcomes Mandate National Integration With Cannabis as Medicine

Who this might be right for
Chronic PainChronic Pain SyndromeChronic Pain Due to Injury+30 more
OMNI Medical Services, LLC 200,000
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