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Results for “Developmental and Epileptic Encephalopathies”

47 trials

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Showing 20 of 47 results

Early research (Phase 1)Looking for participantsNCT06700811
What this trial is testing

Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies

Who this might be right for
Developmental and Epileptic EncephalopathiesEpileptic SpasmsGenetic Epilepsy+1 more
Heather Olson 10
Not applicableLooking for participantsNCT06855901
What this trial is testing

Home Ultra-long Term EEG Monitoring for Rare Epilepsies and Developmental and Epileptic Encephalopathies

Who this might be right for
EpilepsiesEpilepsies, FocalEpileptic Encephalopathy
Azienda Ospedaliero-Universitaria di Modena 30
Testing effectiveness (Phase 2)Study completedNCT05364021
What this trial is testing

Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies

Who this might be right for
Developmental and Epileptic EncephalopathyDravet SyndromeLennox Gastaut Syndrome
Longboard Pharmaceuticals 52
Testing effectiveness (Phase 2)Active Not RecruitingNCT05226780
What this trial is testing

Extension Study to Evaluate How Safe and Tolerable NBI-921352 is as an Adjunctive Therapy for Participants With SCN8A-DEE

Who this might be right for
SCN8A Developmental and Epileptic Encephalopathy Syndrome
Neurocrine Biosciences 8
Testing effectiveness (Phase 2)Ended earlyNCT03635073
What this trial is testing

Soticlestat in Adults and Children With Rare Epilepsies

Who this might be right for
EpilepsyDravet Syndrome (DS)Lennox-Gastaut Syndrome (LGS)
Takeda 156
Large-scale testing (Phase 3)Ended earlyNCT04912856
What this trial is testing

An Open-Label Extension of the Study XEN496 (Ezogabine) in Children With KCNQ2-DEE

Who this might be right for
EpilepsyEpilepsy in ChildrenEpilepsy; Seizure+5 more
Xenon Pharmaceuticals Inc. 8
Not applicableLooking for participantsNCT06278428
What this trial is testing

Genotype, Phenotype, and Disease Progression of Developmental Epileptic Encephalopathy With Onset Before 2 Years of Age

Who this might be right for
Epilepsy; SeizureChild DevelopmentGene Abnormality+1 more
Number 2 Children's Hospital, Ho Chi Minh City 50
Testing effectiveness (Phase 2)Temporarily pausedNCT06983158
What this trial is testing

A Clinical Trial of CAP-002 Gene Therapy in Pediatric Patients With Syntaxin-Binding Protein 1 (STXBP1) Encephalopathy

Who this might be right for
Developmental and Epileptic Encephalopathy
Capsida Biotherapeutics, Inc. 12
Large-scale testing (Phase 3)Enrolling By InvitationNCT06908226
What this trial is testing

Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE)

Who this might be right for
Developmental and Epileptic Encephalopathy
Longboard Pharmaceuticals 324
Not applicableAvailableNCT06149663
What this trial is testing

Intermediate-Size Expanded Access Protocol (EAP) for LP352

Who this might be right for
Dravet SyndromeLennox Gastaut SyndromeDevelopmental and Epileptic Encephalopathies
Longboard Pharmaceuticals
Not applicableLooking for participantsNCT06792396
What this trial is testing

Study of Patients with Electrical Status Epilepticus in Sleep

Who this might be right for
Electrical Status Epilepticus in Sleep
East Suffolk and North Essex NHS Foundation Trust 20
Testing effectiveness (Phase 2)Looking for participantsNCT05737784
What this trial is testing

A Clinical Trial of PRAX-222 in Pediatric Participants With Early Onset SCN2A Developmental and Epileptic Encephalopathy

Who this might be right for
SCN2A-DEEEpilepsy
Praxis Precision Medicines 60
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Large-scale testing (Phase 3)Active Not RecruitingNCT05818553
What this trial is testing

A Clinical Trial of PRAX-562 in Subjects With Developmental and Epileptic Encephalopathies (DEE)

Who this might be right for
SCN2A EncephalopathySCN8A Encephalopathy
Praxis Precision Medicines 77
Testing effectiveness (Phase 2)Looking for participantsNCT06401538
What this trial is testing

BMB-101 in Absence Epilepsy and DEE

Who this might be right for
Absence EpilepsyJeavons SyndromeDravet Syndrome+1 more
Bright Minds Biosciences Pty Ltd 20
Not applicableEnded earlyNCT04537832
What this trial is testing

Natural History Study of Infants and Children With Developmental and Epileptic Encephalopathies

Who this might be right for
Dravet Syndrome
Encoded Therapeutics 58
Not applicableLooking for participantsNCT06380192
What this trial is testing

Developmental and Epileptic Encephalopathy of Genetic Etiology: Natural History Through Reuse of Clinical Data

Who this might be right for
Developmental and Epileptic Encephalopathy
Imagine Institute 400
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Not applicableLooking for participantsNCT01238250
What this trial is testing

Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight

Who this might be right for
16P11.2 Deletion Syndrome16p11.2 Duplications1Q21.1 Deletion+181 more
Simons Searchlight 100,000
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07221968
What this trial is testing

Melatonin for the Treatment of DEE-SWAS

Who this might be right for
CSWSDevelopmental and/or Epileptic EncephalopathiesElectrical Status Epilepticus in Sleep
Hugo W. Moser Research Institute at Kennedy Krieger, Inc. 3
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