Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Developmental and Epileptic Encephalopathy”

51 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 51 results

Testing effectiveness (Phase 2)Study completedNCT03166215
What this trial is testing

Study of TAK-935 as an Adjunctive Therapy in Participants With Developmental and/or Epileptic Encephalopathies

Who this might be right for
Developmental and/or Epileptic Encephalopathies
Takeda 18
Not applicableUnknownNCT05157737
What this trial is testing

Clinical Phenotype and Omics Study of KCNQ2-related Epilepsy

Who this might be right for
KCNQ2-related Epilepsy
Fudan University 200
Post-approval studies (Phase 4)UnknownNCT05232630
What this trial is testing

Fenfluramine for the Treatment of Different Types of Developmental and Epileptic Encephalopathies: a Pilot Trial Exploring Epileptic and Non-epileptic Outcomes

Who this might be right for
Refractory EpilepsySYNGAP1 EncephalopathySTXBP1 Encephalopathy With Epilepsy+3 more
Hospital Ruber Internacional 20
Large-scale testing (Phase 3)Ended earlyNCT04912856
What this trial is testing

An Open-Label Extension of the Study XEN496 (Ezogabine) in Children With KCNQ2-DEE

Who this might be right for
EpilepsyEpilepsy in ChildrenEpilepsy; Seizure+5 more
Xenon Pharmaceuticals Inc. 8
Testing effectiveness (Phase 2)Ended earlyNCT06983158
What this trial is testing

A Clinical Trial of CAP-002 Gene Therapy in Pediatric Patients With Syntaxin-Binding Protein 1 (STXBP1) Encephalopathy

Who this might be right for
Developmental and Epileptic Encephalopathy
Capsida Biotherapeutics, Inc. 1
Not applicableLooking for participantsNCT01793168
What this trial is testing

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Who this might be right for
Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more
Sanford Health 20,000
Testing effectiveness (Phase 2)Ended earlyNCT05226780
What this trial is testing

Extension Study to Evaluate How Safe and Tolerable NBI-921352 is as an Adjunctive Therapy for Participants With SCN8A-DEE

Who this might be right for
SCN8A Developmental and Epileptic Encephalopathy Syndrome
Neurocrine Biosciences 8
Large-scale testing (Phase 3)Looking for participantsNCT07019922
What this trial is testing

A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

Who this might be right for
Epileptic EncephalopathySCN2A Encephalopathy
Praxis Precision Medicines 40
Not applicableLooking for participantsNCT06278428
What this trial is testing

Genotype, Phenotype, and Disease Progression of Developmental Epileptic Encephalopathy With Onset Before 2 Years of Age

Who this might be right for
Epilepsy; SeizureChild DevelopmentGene Abnormality+1 more
Number 2 Children's Hospital, Ho Chi Minh City 50
Not applicableUnknownNCT05722990
What this trial is testing

Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam

Who this might be right for
Whole Exome SequencingEpileptic Encephalopathy
Number 2 Children's Hospital, Ho Chi Minh City 150
Not applicableLooking for participantsNCT06092346
What this trial is testing

A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Who this might be right for
AMPD3, OMIM*102772, AMP Deaminase DeficiencyAK1, OMIM *103000, Adenylate Kinase DeficiencyAMPD1, OMIM *102770, Myopathy Due to Myoadenylate Deaminase Deficiency+25 more
National Human Genome Research Institute (NHGRI)
Not applicableActive Not RecruitingNCT06500260
What this trial is testing

CNKSR2 Natural History Study

Who this might be right for
Developmental DysphasiaEpileptic Encephalopathy, Childhood-OnsetX-Linked Intellectual Disability
University of California, San Francisco 20
Not applicableAvailableNCT06149663
What this trial is testing

Intermediate-Size Expanded Access Protocol (EAP) for LP352

Who this might be right for
Dravet SyndromeLennox Gastaut SyndromeDevelopmental and Epileptic Encephalopathies
Longboard Pharmaceuticals
Large-scale testing (Phase 3)Not Yet RecruitingNCT07723976
What this trial is testing

Evaluate the Safety and Efficacy of CBD-OS in Participants With DEE

Who this might be right for
Developmental and Epileptic Encephalopathy (DEE)
Jazz Pharmaceuticals 120
Not applicableLooking for participantsNCT07531511
What this trial is testing

SLC6A1-NDD Prospective Longitudinal Natural History Study

Who this might be right for
SLC6A1 Neurodevelopmental Disorder (NDD)Developmental and Epileptic Encephalopathies (DEE)
UCB Biopharma SRL 60
Not applicableLooking for participantsNCT06855901
What this trial is testing

Home Ultra-long Term EEG Monitoring for Rare Epilepsies and Developmental and Epileptic Encephalopathies

Who this might be right for
EpilepsiesEpilepsies, FocalEpileptic Encephalopathy
Azienda Ospedaliero-Universitaria di Modena 30
Testing effectiveness (Phase 2)Ended earlyNCT04873869
What this trial is testing

Study to Evaluate NBI-921352 as Adjunctive Therapy in Subjects With SCN8A Developmental and Epileptic Encephalopathy Syndrome (SCN8A-DEE)

Who this might be right for
SCN8A Developmental and Epileptic Encephalopathy Syndrome
Neurocrine Biosciences 8
Testing effectiveness (Phase 2)Looking for participantsNCT07227857
What this trial is testing

A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy

Who this might be right for
Epileptic Encephalopathy
Institut de Recherches Internationales Servier 20
Not applicableNot Yet RecruitingNCT07396883
What this trial is testing

Developmental and Epileptic Encephalopathies Diagnosed Via Long-read Genome Sequencing

Who this might be right for
Developmental and Epileptic EncephalopathyEpilepsy in Children
University Hospital, Strasbourg, France 20
Very early researchLooking for participantsNCT07675746
What this trial is testing

Evaluate the Safety and Pharmacokinetics of RC001 in Children With Dravet Syndrome

Who this might be right for
Dravet Syndrome (DS)
Second Affiliated Hospital of Guangzhou Medical University 8
Next Page
999