Testing effectiveness (Phase 2)Study completedNCT01469247What this trial is testingDiffuse Intrinsic Pontine Glioma (DIPG) Reirradiation (ReRT)Who this might be right forBrain Cancer M.D. Anderson Cancer Center 12
Very early researchActive Not RecruitingNCT03893487What this trial is testingFimepinostat in Treating Brain Tumors in Children and Young AdultsWho this might be right forDiffuse Intrinsic Pontine GliomaRecurrent Anaplastic AstrocytomaRecurrent Glioblastoma+2 more Sabine Mueller, MD, PhD 30
Testing effectiveness (Phase 2)UnknownNCT02233049What this trial is testingBiological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) EradicationWho this might be right forDiffuse Intrinsic Pontine Glioma Gustave Roussy, Cancer Campus, Grand Paris 250
Early research (Phase 1)Ended earlyNCT03396575What this trial is testingBrain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I)Who this might be right forDiffuse Intrinsic Pontine Glioma (DIPG)Brain Stem Glioma University of Florida 11
Early research (Phase 1)Study completedNCT01688401What this trial is testingIntra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG).Who this might be right forDiffuse Intrinsic Pontine Glioma (DIPG) Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 3
Testing effectiveness (Phase 2)Temporarily pausedNCT05123534What this trial is testingSonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Patients with DIPGWho this might be right forDiffuse Intrinsic Pontine GliomaDiffuse Midline Glioma SonALAsense, Inc. 15
Not applicableLooking for participantsNCT03101813What this trial is testingInternational Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and RepositoryWho this might be right forDiffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-MutantDiffuse Midline Glioma Children's Hospital Medical Center, Cincinnati 1,500
Testing effectiveness (Phase 2)Looking for participantsNCT05843253What this trial is testingStudy of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutantWho this might be right forHigh Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+7 more Nationwide Children's Hospital 120
Testing effectiveness (Phase 2)Looking for participantsNCT05615623What this trial is testingBlood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric DIPGWho this might be right forBrain Tumor InSightec 10
Testing effectiveness (Phase 2)Ended earlyNCT02607124What this trial is testingA Phase I/II Study of Ribociclib,a CDK4/6 Inhibitor, Following Radiation TherapyWho this might be right forHigh Grade GliomaDiffuse Intrinsic Pontine GliomaBithalamic High Grade Glioma Children's Hospital Medical Center, Cincinnati 11
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06639607What this trial is testingPEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and EpendymomaWho this might be right forDiffuse Midline GliomaDiffuse Midline High-grade GliomaMedulloblastoma+1 more Washington University School of Medicine 68
Early research (Phase 1)Study completedNCT02644460What this trial is testingAbemaciclib in Children With DIPG or Recurrent/Refractory Solid TumorsWho this might be right forDiffuse Intrinsic Pontine GliomaBrain Tumor, RecurrentSolid Tumor, Recurrent+5 more Emory University 53
Testing effectiveness (Phase 2)Study completedNCT02750891What this trial is testingDSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade GliomasWho this might be right forGlioblastomaDiffuse Intrinsic Pontine Glioma Sumitomo Pharma Co., Ltd. 18
Early research (Phase 1)Active Not RecruitingNCT03389802What this trial is testingPhase I Study of APX005M in Pediatric Central Nervous System TumorsWho this might be right forGlioblastoma MultiformeHigh-grade Astrocytoma Not Otherwise Specified (NOS)CNS Primary Tumor, Not Otherwise Specified (NOS)+3 more Pediatric Brain Tumor Consortium 32
Testing effectiveness (Phase 2)Study completedNCT01777633What this trial is testingPalliative Re-irradiation for Progressive Diffuse Intrinsic Pontine Glioma (DIPG) in ChildrenWho this might be right forPediatric Malignant Brain Tumor -Diffuse Intrinsic Pontine Glioma Hadassah Medical Organization 15
Testing effectiveness (Phase 2)Study completedNCT02960230What this trial is testingH3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other GliomasWho this might be right forDiffuse Intrinsic Pontine GliomaGliomaDiffuse Midline Glioma, H3 K27M-Mutant Sabine Mueller, MD, PhD 50
Not applicableActive Not RecruitingNCT03033992What this trial is testingOptune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPGWho this might be right forMalignant GliomaEpendymomaDiffuse Intrinsic Pontine Glioma Children's Oncology Group 80
Testing effectiveness (Phase 2)Looking for participantsNCT06465199What this trial is testingEflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and SarcomasWho this might be right forAtypical Teratoid/Rhabdoid TumorEmbryonal Tumor With Multilayered RosettesEwing Sarcoma+4 more Milton S. Hershey Medical Center 289
Testing effectiveness (Phase 2)Study completedNCT01837862What this trial is testingA Phase I Study of Mebendazole for the Treatment of Pediatric GliomasWho this might be right forPilomyxoid AstrocytomaPilocytic AstrocytomaGlioma, Astrocytic+9 more Julie Krystal 36
Testing effectiveness (Phase 2)Study completedNCT03257631What this trial is testingPomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain TumorsWho this might be right forCentral Nervous System NeoplasmsMedulloblastoma Celgene 53