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Results for “Diffuse Large B Cell Lymphoma, Gene Mutation”

17 trials

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Showing 17 of 17 results

Testing effectiveness (Phase 2)UnknownNCT04023916
What this trial is testing

Sintilimab Plus R-CHOP as the First-line Treatment in Patients With Diffuse Large B-Cell Lymphoma.

Who this might be right for
Diffuse Large B-Cell LymphomaSintilimabTP53 Mutation
Chinese Academy of Medical Sciences 30
Not applicableUnknownNCT04825899
What this trial is testing

Gene Abnormalities and Prognosis in Diffuse Large B-cell Lymphoma

Who this might be right for
Diffuse Large B Cell Lymphoma, Gene Mutation
Fudan University 100
Testing effectiveness (Phase 2)Temporarily pausedNCT04668365
What this trial is testing

Zanubrutinib Combined With Standard Chemotherapy in the Treatment for Patients With Diffuse Large B Cell Lymphoma

Who this might be right for
Diffuse Large B Cell LymphomaCD79A Gene MutationCD79B Gene Mutation
Henan Cancer Hospital 59
Very early researchEnded earlyNCT03272633
What this trial is testing

Irradiated Donor Cells Following Stem Cell Transplant in Controlling Cancer in Patients With Hematologic Malignancies

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia in RemissionHematopoietic Cell Transplantation Recipient+16 more
Rutgers, The State University of New Jersey 2
Testing effectiveness (Phase 2)Looking for participantsNCT06846463
What this trial is testing

Zanubrutinib in Patients With DLBCL and MYD88 or NOTCH1 Mutation or CD5+

Who this might be right for
Diffuse Large B-cell LymphomaDLBCL - Diffuse Large B Cell Lymphoma
Virginia Commonwealth University 21
Testing effectiveness (Phase 2)UnknownNCT05290337
What this trial is testing

ZR-CHOP in DLBCL With Specific Gene Abnormality

Who this might be right for
Diffuse Large B Cell Lymphoma
Fudan University 62
Testing effectiveness (Phase 2)Active Not RecruitingNCT03162536
What this trial is testing

Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001)

Who this might be right for
Lymphoma, B-CellSmall Lymphocytic LymphomaChronic Lymphocytic Leukemia+6 more
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) 190
Testing effectiveness (Phase 2)Ended earlyNCT02282358
What this trial is testing

Study of Mocetinostat in Selected Patients With Mutations of Acetyltransferase Genes in Relapsed and Refractory Diffuse Large B-Cell Lymphoma and Follicular Lymphoma

Who this might be right for
LymphomaRelapsed and RefractoryDiffuse Large B-Cell Lymphoma and Follicular Lymphoma
Memorial Sloan Kettering Cancer Center 7
Testing effectiveness (Phase 2)Study completedNCT03456726
What this trial is testing

Study of Tazemetostat in Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma With EZH2 Gene Mutation

Who this might be right for
Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma
Eisai Co., Ltd. 20
Testing effectiveness (Phase 2)Study completedNCT02252146
What this trial is testing

Dose Escalation Study in Patients With Relapsed or Refractory DLBCL and MyD88 L265P Mutation

Who this might be right for
Diffuse Large B Cell Lymphoma
Idera Pharmaceuticals, Inc. 6
Large-scale testing (Phase 3)Study completedNCT00719472
What this trial is testing

Rituximab Alternative Dosing Rate in Patients With Previously Untreated Diffuse Large B-cell or Follicular Non-Hodgkin's Lymphoma (RATE)

Who this might be right for
Non-Hodgkin's Lymphoma
Genentech, Inc. 451
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05280626
What this trial is testing

First-line Treatment of P53 Mutation With PD-L1 Expression in DLBCL With Anti-PD-1 Mab and R-CHOP

Who this might be right for
Diffuse Large B-Cell Lymphoma
Innovent Biologics (Suzhou) Co. Ltd. 100
Early research (Phase 1)Ended earlyNCT01402440
What this trial is testing

Study of AEB071 (a Protein Kinase C Inhibitor) in Patients With CD79-mutant Diffuse Large B-Cell Lymphoma

Who this might be right for
Diffuse Large B-Cell Lymphoma
Novartis Pharmaceuticals 15
Early research (Phase 1)Study completedNCT05233033
What this trial is testing

Safety, PK/PD, and Clinical Activity of KT-413 in Adult Patients with Relapsed or Refractory B-cell NHL

Who this might be right for
Non Hodgkin LymphomaDiffuse Large B Cell LymphomaDLBCL+1 more
Kymera Therapeutics, Inc. 7
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06750991
What this trial is testing

CD-RCHOP in ND DLBCL With a Combination of TP53 Mutation and Del(17p)

Who this might be right for
DLBCL
Ruijin Hospital 34
Testing effectiveness (Phase 2)UnknownNCT02481310
What this trial is testing

Combination Chemotherapy, Rituximab, and Ixazomib Citrate in Treating Patients With Non-Hodgkin Lymphoma

Who this might be right for
Adult Burkitt LymphomaB-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Burkitt LymphomaDiffuse Large B-Cell Lymphoma+2 more
Northwestern University 38
Testing effectiveness (Phase 2)Study completedNCT03740529
What this trial is testing

Oral LOXO-305 in Patients With Previously Treated CLL/SLL or NHL

Who this might be right for
Chronic Lymphocytic LeukemiaWaldenstrom MacroglobulinemiaMantle Cell Lymphoma+3 more
Loxo Oncology, Inc. 803