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Results for “Diffuse Midline Glioma”

67 trials

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Showing 20 of 67 results

Early research (Phase 1)Looking for participantsNCT07223034
What this trial is testing

177Lu-PSMA-617 in People With Gliomas

Who this might be right for
GliomaDiffuse Astrocytoma, IDH-Wildtype (Grade 2-4)Glioblastoma, IDH-wildtype+3 more
Memorial Sloan Kettering Cancer Center 20
Testing effectiveness (Phase 2)Temporarily pausedNCT05123534
What this trial is testing

Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Patients with DIPG

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma
SonALAsense, Inc. 15
Early research (Phase 1)Looking for participantsNCT05298995
What this trial is testing

GD2-CAR T Cells for Pediatric Brain Tumours

Who this might be right for
Brain Tumor, PediatricMedulloblastoma, ChildhoodEmbryonal Tumor+4 more
Bambino Gesù Hospital and Research Institute 54
Not applicableLooking for participantsNCT03101813
What this trial is testing

International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-MutantDiffuse Midline Glioma
Children's Hospital Medical Center, Cincinnati 1,500
Early research (Phase 1)Ended earlyNCT04804709
What this trial is testing

Non-Invasive Focused Ultrasound (FUS) With Oral Panobinostat in Children With Progressive Diffuse Midline Glioma (DMG)

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Pontine and Thalamic GliomasDiffuse Midline Glioma, H3 K27M-Mutant
Columbia University 5
Testing effectiveness (Phase 2)Looking for participantsNCT05843253
What this trial is testing

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+7 more
Nationwide Children's Hospital 120
Early research (Phase 1)Study completedNCT04264143
What this trial is testing

CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Pontine and Thalamic GliomasDiffuse Midline Glioma
Luca Szalontay 9
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06639607
What this trial is testing

PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma

Who this might be right for
Diffuse Midline GliomaDiffuse Midline High-grade GliomaMedulloblastoma+1 more
Washington University School of Medicine 68
Early research (Phase 1)Not Yet RecruitingNCT07455045
What this trial is testing

A Phase I Study of FZ-AD005 in Patients With High-Grade Glioma (HGG)

Who this might be right for
High Grade Glioma (III or IV)Diffuse Midline Glioma (DMG)Glioblastoma (GBM)
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. 40
Testing effectiveness (Phase 2)Study completedNCT02960230
What this trial is testing

H3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other Gliomas

Who this might be right for
Diffuse Intrinsic Pontine GliomaGliomaDiffuse Midline Glioma, H3 K27M-Mutant
Sabine Mueller, MD, PhD 50
Early research (Phase 1)Looking for participantsNCT06894979
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

Who this might be right for
Childhood AstrocytomaChildhood Diffuse Intrinsic Pontine GliomaChildhood Diffuse Midline Glioma+2 more
Children's Oncology Group 54
Testing effectiveness (Phase 2)Looking for participantsNCT04870944
What this trial is testing

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

Who this might be right for
Diffuse Midline Glioma, H3 K27-AlteredMetastatic Malignant Neoplasm in the Central Nervous SystemRecurrent Diffuse Intrinsic Pontine Glioma+7 more
Children's Oncology Group 63
Early research (Phase 1)Looking for participantsNCT06624371
What this trial is testing

Atovaquone Combined With Radiation in Children With Malignant Brain Tumors

Who this might be right for
High-grade GliomaMedulloblastomaDiffuse Intrinsic Pontine Glioma+1 more
Emory University 18
Not applicableLooking for participantsNCT06000787
What this trial is testing

MCT for the Harvard/UCSF ROBIN Center

Who this might be right for
Glioma, Childhood BrainstemNeuroblastoma
Brigham and Women's Hospital 47
Early research (Phase 1)Active Not RecruitingNCT05478837
What this trial is testing

Genetically Modified Cells (KIND T Cells) for the Treatment of HLA-A*0201-Positive Patients With H3.3K27M-Mutated Glioma

Who this might be right for
Diffuse Midline Glioma, H3 K27M-Mutant
University of California, San Francisco 12
Early research (Phase 1)Not Yet RecruitingNCT07331064
What this trial is testing

Gallium Maltolate for the Treatment of Pediatric Patients With Relapsed or Refractory Pediatric High-Grade Glioma and Atypical Teratoid Rhabdoid Tumor

Who this might be right for
High Grade GliomasAtypical Teratoid Rhabdoid Tumors (ATRT)Diffuse Midline Glioma+2 more
Sarah Rumler 15
Large-scale testing (Phase 3)Study completedNCT00538850
What this trial is testing

Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain

Who this might be right for
Cancer
INSYS Therapeutics Inc 130
Early research (Phase 1)Ended earlyNCT04771897
What this trial is testing

BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG)

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-Mutant
Bexion Pharmaceuticals, Inc. 10
Early research (Phase 1)Looking for participantsNCT04541082
What this trial is testing

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

Who this might be right for
Central Nervous System NeoplasmsGlioblastomaGliosarcoma, Adult+20 more
Jazz Pharmaceuticals 102
Testing effectiveness (Phase 2)Study completedNCT00492089
What this trial is testing

Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer

Who this might be right for
Adult Anaplastic AstrocytomaAdult Anaplastic EpendymomaAdult Anaplastic Meningioma+84 more
National Cancer Institute (NCI) 11
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