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Results for “Diffuse Midline Glioma”

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Showing 20 of 0 results

Early research (Phase 1)Active Not RecruitingNCT05768880
What this trial is testing

Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline GliomaRecurrent CNS Tumor, Adult+2 more
Seattle Children's Hospital 72
Testing effectiveness (Phase 2)Ended earlyNCT05500508
What this trial is testing

Oral AMXT 1501 Dicaprate in Combination With IV DFMO

Who this might be right for
CancerSolid TumorSolid Carcinoma+17 more
Aminex Therapeutics, Inc. 15
Early research (Phase 1)Study completedNCT00030498
What this trial is testing

Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction

Who this might be right for
Adult Anaplastic AstrocytomaAdult Anaplastic EpendymomaAdult Anaplastic Oligodendroglioma+83 more
National Cancer Institute (NCI) 75
Early research (Phase 1)Ended earlyNCT04771897
What this trial is testing

BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG)

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-Mutant
Bexion Pharmaceuticals, Inc. 10
Early research (Phase 1)Not Yet RecruitingNCT07796061
What this trial is testing

Blood-Brain Barrier Disruption Using Exablate Magnetic Resonance-Guided Low Intensity Focused Ultrasound With Microbubbles in Combination With T-Cell Infusion in Patients With Newly Diagnosed Diffuse Midline Glioma (LIFT)

Who this might be right for
Pontine Diffuse Midline GliomaDiffuse Intrinsic Pontine GliomaThalamic Diffuse Midline Glioma
Children's National Research Institute 45
Testing effectiveness (Phase 2)Looking for participantsNCT07589257
What this trial is testing

VRT106 in Combination With Radiotherapy in Adult Patients With Diffuse Midline Glioma / Diffuse Intrinsic Pontine Glioma

Who this might be right for
Diffuse Midline Glioma, H3 K27M-MutantDiffuse Intrinsic Pontine Glioma
Guangzhou Virotech Pharmaceutical Co., Ltd. 10
Testing effectiveness (Phase 2)Ended earlyNCT02758366
What this trial is testing

Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma

Who this might be right for
Glioblastoma (GBM)DIPGBrainstem Glioma, Pediatric+5 more
Meyer Children's Hospital IRCCS 21
Large-scale testing (Phase 3)Study completedNCT00538850
What this trial is testing

Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain

Who this might be right for
Cancer
INSYS Therapeutics Inc 130
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07389278
What this trial is testing

Combination ADI-PEG 20, TMZ, and RT for Treatment of Newly Diagnosed High-grade Glioma (HGG)

Who this might be right for
GlioblastomaHigh-Grade Glioma (WHO III-IV)High-grade Glioma+2 more
Sabine Mueller, MD, PhD 97
Early research (Phase 1)Not Yet RecruitingNCT07455045
What this trial is testing

A Phase I Study of FZ-AD005 in Patients With High-Grade Glioma (HGG)

Who this might be right for
High Grade Glioma (III or IV)Diffuse Midline Glioma (DMG)Glioblastoma (GBM)
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. 40
Early research (Phase 1)Active Not RecruitingNCT05413304
What this trial is testing

Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral Microdialysis

Who this might be right for
Glioma
National Cancer Institute (NCI) 1
Early research (Phase 1)Looking for participantsNCT06624371
What this trial is testing

Atovaquone Combined With Radiation in Children With Malignant Brain Tumors

Who this might be right for
High-grade GliomaMedulloblastomaDiffuse Intrinsic Pontine Glioma+1 more
Emory University 18
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Not applicableNot Yet RecruitingNCT06093165
What this trial is testing

RE-irradiation of Diffuse MIdline Glioma paTients

Who this might be right for
Diffuse Midline Glioma, H3 K27M-MutantDiffuse Intrinsic Pontine GliomaDiffuse Glioma+3 more
Rigshospitalet, Denmark 59
Early research (Phase 1)Looking for participantsNCT05544526
What this trial is testing

CAR T Cells to Target GD2 for DMG

Who this might be right for
Diffuse Midline Glioma, H3 K27M-Mutant
University College, London 12
Testing effectiveness (Phase 2)Temporarily pausedNCT06639607
What this trial is testing

PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma

Who this might be right for
Diffuse Midline GliomaDiffuse Midline High-grade GliomaMedulloblastoma+1 more
Washington University School of Medicine 68
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07562971
What this trial is testing

Focused Ultrasound Blood-Brain Barrier Opening in Pontine Diffuse Midline Glioma to Enhance Temozolomide Therapy: Pilot Feasibility Study (FIDES)

Who this might be right for
Diffuse Midline Glioma, H3 K27-Altered
UMC Utrecht 20
Early research (Phase 1)Looking for participantsNCT05762419
What this trial is testing

FUS Etoposide for DMG

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-Mutant
Columbia University 10
Testing effectiveness (Phase 2)Looking for participantsNCT07680439
What this trial is testing

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

Who this might be right for
Diffuse Intrinsic Pontine GliomaDIPGBrain Tumor+9 more
BrainChild Bio, Inc 75
Testing effectiveness (Phase 2)Ended earlyNCT02525692
What this trial is testing

Oral ONC201 in Adult Recurrent Glioblastoma

Who this might be right for
GlioblastomaDiffuse Midline GliomaH3 K27M Glioma+3 more
Jazz Pharmaceuticals 84
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