Not applicableStudy completedNCT00525837What this trial is testingStudy of Mood Effects of Varenicline (Chantix) in Depressed Outpatient SmokersWho this might be right forDepressive DisorderSmoking Butler Hospital 18
Not applicableStudy completedNCT05084924What this trial is testingInvestigating the Causal Role of Prefrontal Control in Decision-making in Patients With AnhedoniaWho this might be right forMajor Depressive DisorderAnhedonia University of North Carolina, Chapel Hill 35
Not applicableLooking for participantsNCT05240352What this trial is testingDeveloping Brain Imaging Analysis Expertise for Personalizing Transcranial Electric Stimulation in Anhedonia Treatment of Patients With Bipolar DepressionWho this might be right forAnhedonia The University of Texas Health Science Center, Houston 45
Not applicableUnknownNCT05355142What this trial is testingAn Intervention Study of Anhedonia and Pain Empathy in DepressionWho this might be right forTreatment Resistant DepressionProblem Management PlusEvent-Related Potentials Anhui Medical University 66
Not applicableLooking for participantsNCT06096740What this trial is testingPsychotherapy Effects on Reward Processing in PTSDWho this might be right forPost Traumatic Stress DisorderDiminished PleasureAnhedonia+3 more University of Texas at Austin 120
Not applicableStudy completedNCT05544071What this trial is testingIndividualized dlPFC-NAcc Modulation for Anhedonia in adMDDWho this might be right forMajor Depressive DisorderRepetitive Transcranial Magnetic Stimulation Xijing Hospital 88
Not applicableStudy completedNCT02905604What this trial is testingMagnetic Stimulation of the Brain in Schizophrenia or DepressionWho this might be right forSchizophreniaDepressionAnhedonia+1 more Uppsala University 60
Not applicableLooking for participantsNCT05691439What this trial is testingMechanisms of Depression and Anhedonia in Adolescents: Linking Sleep to Reward- and Stress-Related Brain FunctionWho this might be right forDepression in Adolescence University of Oregon 150
Not applicableActive Not RecruitingNCT06035562What this trial is testingPromoting Positive Emotional Functioning in Police and Military PopulationsWho this might be right forAnhedonia University of Manitoba 65
Testing effectiveness (Phase 2)Study completedNCT05165394What this trial is testingStudy to Evaluate the Efficacy and Safety of Once-Weekly Oral NBI-1065846 in the Treatment of Anhedonia in MDDWho this might be right forAnhedoniaMajor Depressive Disorder Neurocrine Biosciences 93
Post-approval studies (Phase 4)Looking for participantsNCT05282277What this trial is testingExamining the Effects of Estradiol on Neural and Molecular Response to RewardWho this might be right forDepressionPsychosisAnhedonia University of North Carolina, Chapel Hill 103
Not applicableStudy completedNCT05849675What this trial is testingPitolisant Effects on Affect and Cognition Exploratory Study (PEACE Study)Who this might be right forAnhedoniaCognitive Function University of Oxford 58
Early research (Phase 1)Looking for participantsNCT07386730What this trial is testingPsychedelics in Healthy Older Adults With Low Well-beingWho this might be right forAnhedonia in Healthy VolunteersOlder Adults (50-90 Years) Jennifer Mitchell 80
Testing effectiveness (Phase 2)Study completedNCT03319953What this trial is testingA Randomized, Double-Blind, Placebo Controlled, Two-Period Cross-Over, Proof of Activity Study to Evaluate the Effects of TAK-041 on Motivational Anhedonia as Add-On to Antipsychotics in Participants With Stable SchizophreniaWho this might be right forStable Schizophrenia Neurocrine Biosciences 23
Not applicableStudy completedNCT00082030What this trial is testingFunction of Catecholamines in the Brain During DepressionWho this might be right forDepressionInvolutional National Institute of Mental Health (NIMH) 71
Post-approval studies (Phase 4)Study completedNCT02859103What this trial is testingDimensional Approach to Evaluate Reward Processing in Major Depressive Disorder Pre- and Post-Desvenlafaxine TreatmentWho this might be right forDepressionAnhedonia Unity Health Toronto 56
Not applicableStudy completedNCT05537285What this trial is testingIndividualized Neuromodulation for Anhedonic DepressionWho this might be right forMDDAnhedonia University of California, San Diego 60
Not applicableLooking for participantsNCT07637773What this trial is testingInvestigating the Efficacy and Mechanisms of Individualized tACS Targeting Anhedonia in Late-Life DepressionWho this might be right forLate-Life DepressionAnhedonia Jie Li 80
Testing effectiveness (Phase 2)Study completedNCT06230757What this trial is testingPsilocybin for Treatment-Resistant DepressionWho this might be right forMajor Depressive DisorderAnhedoniaTreatment Resistant Depression University of Colorado, Denver 20
Not applicableLooking for participantsNCT07663019What this trial is testingChatbot Intervention Effects on Belief Updating in AnhedoniaWho this might be right forHealthy University of Electronic Science and Technology of China 80