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Results for “Direct-acting Antivirals”

179 trials

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Showing 20 of 179 results

Large-scale testing (Phase 3)Study completedNCT01851330
What this trial is testing

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin for the Treatment of HCV (ION-3)

Who this might be right for
Chronic Hepatitis C Virus
Gilead Sciences 647
Large-scale testing (Phase 3)Study completedNCT02707601
What this trial is testing

Efficacy, Safety, and Tolerability of Ledipasvir/Sofosbuvir (LDV/SOF) Treatment for HIV/HCV Co-infected Participants Who Switch to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) or Emtricitabine/Rilpivirine/Tenofovir Alafenamide (F/R/TAF) Prior to LDV/SOF HCV Treatment

Who this might be right for
HIV-1 InfectionHCV Infection
Gilead Sciences 150
Not applicableStudy completedNCT03318887
What this trial is testing

Impact of Sofosbuvir and Daclatasvir Concentration on HCV RNA

Who this might be right for
Hepatitis C
Hospices Civils de Lyon 130
Not applicableStudy completedNCT03935906
What this trial is testing

Reaching mEthadone Users Attending Community pHarmacies With HCV

Who this might be right for
Hepatitis C
University of Dundee 210
Large-scale testing (Phase 3)Study completedNCT02487030
What this trial is testing

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed Dose Combination, With or Without Ribavirin, in Egyptian Adults With Chronic Genotype 4 HCV Infection

Who this might be right for
Hepatitis C Virus Infection
Gilead Sciences 255
Large-scale testing (Phase 3)Study completedNCT02472886
What this trial is testing

Safety and Efficacy of Ledipasvir/Sofosbuvir in Adults With Chronic HCV Infection

Who this might be right for
Hepatitis C Virus Infection
Gilead Sciences 153
Not applicableEnded earlyNCT03483987
What this trial is testing

Re-treatment of HCV Following DAA Failure

Who this might be right for
Chronic Hepatitis C
Sanjay Gandhi Postgraduate Institute of Medical Sciences 18
Not applicableUnknownNCT05376943
What this trial is testing

Possible Differences in HCC Course Depending on DAA Treatment

Who this might be right for
Carcinoma, HepatocellularHepatitis C Virus Infection, Response to Therapy ofDrug Effect+3 more
Medical University of Warsaw 100
Post-approval studies (Phase 4)WithdrawnNCT02959359
What this trial is testing

DAA in the Risk of Recurrence After Curative Treatment of HCC

Who this might be right for
Hepatocellular Carcinoma
Taipei Veterans General Hospital, Taiwan
Not applicableStudy completedNCT03566966
What this trial is testing

Autoantibodies and Direct-acting Antivirals

Who this might be right for
Viral Hepatitis CTherapy Adverse Effect
University of Bari 191
Not applicableUnknownNCT04211844
What this trial is testing

Metabolic Changes in Chronic HCV Patients Receiving DAAS

Who this might be right for
Chronic Hepatitis C
Ain Shams University 100
Not applicableUnknownNCT03687229
What this trial is testing

The Effect Of DAAs on miRNA-122 And Insulin Resistance In Chronic HCV Patients

Who this might be right for
Chronic Hepatitis c
Assiut University 60
Not applicableUnknownNCT02904603
What this trial is testing

Immune Monitoring of Hepatitis C Under DAA Therapy

Who this might be right for
Hepatitis C
University of Regensburg 100
Not applicableStudy completedNCT03884062
What this trial is testing

Clinical Impacts of Achieving SVR in Patients With Advanced Hepatic Fibrosis Related to Chronic HCV Treated With Direct Acting Antivirals

Who this might be right for
HCC in Chronic HCV Patients With Advanced Liver Fibrosis
Egyptian Liver Hospital 3,000
Testing effectiveness (Phase 2)Study completedNCT01225380
What this trial is testing

Response-Guided Duration of Combination Therapy With GS-9190, GS-9256, Pegasys® and Copegus® in Previously Untreated Subjects With Genotype 1 Chronic Hepatitis C

Who this might be right for
Chronic Hepatitis C Infection
Gilead Sciences 324
Large-scale testing (Phase 3)Study completedNCT01625338
What this trial is testing

Open-Label Study of Sofusbuvir+Ribavirin With or Without Peginterferon Alfa-2a in Subjects With Chronic HCV Infection Who Participated in Prior Gilead HCV Studies

Who this might be right for
Chronic Hepatitis C
Gilead Sciences 534
Testing effectiveness (Phase 2)Ended earlyNCT02605304
What this trial is testing

12 Weeks of Ledipasvir (LDV)/Sofosbuvir (SOF) With Weight-based Ribavirin vs. 24 Weeks of LDV/SOF

Who this might be right for
HIV-1 InfectionHepatitis C
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections 7
Not applicableStudy completedNCT03707080
What this trial is testing

Direct Acting Antiviral-Post Authorization Safety Study

Who this might be right for
Hepatitis CHepatocellular Carcinoma
Target PharmaSolutions, Inc. 42
Post-approval studies (Phase 4)Study completedNCT01743521
What this trial is testing

DAA Based Therapy for Recently Acquired Hepatitis C (DARE-C)

Who this might be right for
Hepatitis C, Chronic
Kirby Institute 14
Post-approval studies (Phase 4)Study completedNCT02533934
What this trial is testing

Sofosbuvir Based DAA Therapy in HIV/HCV Coinfected Pre or Post Liver Transplant

Who this might be right for
HIVHepatitis CCirrhosis
University of California, San Francisco 68
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